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The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability.

  • Read more about The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability.

Nicotinamide riboside kinase structures reveal new pathways to NAD+.

  • Read more about Nicotinamide riboside kinase structures reveal new pathways to NAD+.

Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain.

  • Read more about Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain.

The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins.

  • Read more about The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins.

Structural and functional characterization of the human protein kinase ASK1.

  • Read more about Structural and functional characterization of the human protein kinase ASK1.

Structure determination of the motor domain of yeast kinesin kar3 by x-ray crystallography.

  • Read more about Structure determination of the motor domain of yeast kinesin kar3 by x-ray crystallography.

In situ proteolysis for protein crystallization and structure determination.

  • Read more about In situ proteolysis for protein crystallization and structure determination.

Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation.

  • Read more about Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation.

Mechanism and substrate recognition of human holo ACP synthase.

  • Read more about Mechanism and substrate recognition of human holo ACP synthase.

L3MBTL1 recognition of mono- and dimethylated histones.

  • Read more about L3MBTL1 recognition of mono- and dimethylated histones.

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