The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability. Read more about The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability.
Nicotinamide riboside kinase structures reveal new pathways to NAD+. Read more about Nicotinamide riboside kinase structures reveal new pathways to NAD+.
Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain. Read more about Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain.
The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins. Read more about The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins.
Structural and functional characterization of the human protein kinase ASK1. Read more about Structural and functional characterization of the human protein kinase ASK1.
Structure determination of the motor domain of yeast kinesin kar3 by x-ray crystallography. Read more about Structure determination of the motor domain of yeast kinesin kar3 by x-ray crystallography.
In situ proteolysis for protein crystallization and structure determination. Read more about In situ proteolysis for protein crystallization and structure determination.
Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation. Read more about Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation.
Mechanism and substrate recognition of human holo ACP synthase. Read more about Mechanism and substrate recognition of human holo ACP synthase.
L3MBTL1 recognition of mono- and dimethylated histones. Read more about L3MBTL1 recognition of mono- and dimethylated histones.