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Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation.

  • Read more about Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation.

A pilot project to generate affinity reagents to human proteins.

  • Read more about A pilot project to generate affinity reagents to human proteins.

Building skeletally diverse architectures on the Indoline Scaffold: the discovery of a chemical probe of focal adhesion kinase signaling networks.

  • Read more about Building skeletally diverse architectures on the Indoline Scaffold: the discovery of a chemical probe of focal adhesion kinase signaling networks.

Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases.

  • Read more about Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases.

Structural basis and specificity of human otubain 1-mediated deubiquitination.

  • Read more about Structural basis and specificity of human otubain 1-mediated deubiquitination.

Short-term glucocorticoid treatment increases insulin secretion in islets derived from lean mice through multiple pathways and mechanisms.

  • Read more about Short-term glucocorticoid treatment increases insulin secretion in islets derived from lean mice through multiple pathways and mechanisms.

Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum.

  • Read more about Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum.

Structure-activity relationships of human AKR-type oxidoreductases involved in bile acid synthesis: AKR1D1 and AKR1C4.

  • Read more about Structure-activity relationships of human AKR-type oxidoreductases involved in bile acid synthesis: AKR1D1 and AKR1C4.

The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative.

  • Read more about The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative.

Structural insights into the inhibited states of the Mer receptor tyrosine kinase.

  • Read more about Structural insights into the inhibited states of the Mer receptor tyrosine kinase.

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