Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3. Read more about Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3.
Crystal structure of human carbonic anhydrase-related protein VIII reveals the basis for catalytic silencing. Read more about Crystal structure of human carbonic anhydrase-related protein VIII reveals the basis for catalytic silencing.
Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation. Read more about Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation.
Substrate recognition and hydrolysis by a fungal xyloglucan-specific family 12 hydrolase. Read more about Substrate recognition and hydrolysis by a fungal xyloglucan-specific family 12 hydrolase.
Forward genetics in Toxoplasma gondii reveals a family of rhoptry kinases that mediates pathogenesis. Read more about Forward genetics in Toxoplasma gondii reveals a family of rhoptry kinases that mediates pathogenesis.
Buffer optimization of thermal melt assays of Plasmodium proteins for detection of small-molecule ligands. Read more about Buffer optimization of thermal melt assays of Plasmodium proteins for detection of small-molecule ligands.
Structural determinants of G-protein alpha subunit selectivity by regulator of G-protein signaling 2 (RGS2). Read more about Structural determinants of G-protein alpha subunit selectivity by regulator of G-protein signaling 2 (RGS2).
Large-scale structural biology of the human proteome. Read more about Large-scale structural biology of the human proteome.
Crystal structures of human CDY proteins reveal a crotonase-like fold. Read more about Crystal structures of human CDY proteins reveal a crotonase-like fold.
Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors. Read more about Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors.
