Forward genetics in Toxoplasma gondii reveals a family of rhoptry kinases that mediates pathogenesis. Read more about Forward genetics in Toxoplasma gondii reveals a family of rhoptry kinases that mediates pathogenesis.
Buffer optimization of thermal melt assays of Plasmodium proteins for detection of small-molecule ligands. Read more about Buffer optimization of thermal melt assays of Plasmodium proteins for detection of small-molecule ligands.
Structural determinants of G-protein alpha subunit selectivity by regulator of G-protein signaling 2 (RGS2). Read more about Structural determinants of G-protein alpha subunit selectivity by regulator of G-protein signaling 2 (RGS2).
Large-scale structural biology of the human proteome. Read more about Large-scale structural biology of the human proteome.
Crystal structures of human CDY proteins reveal a crotonase-like fold. Read more about Crystal structures of human CDY proteins reveal a crotonase-like fold.
Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors. Read more about Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors.
Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach. Read more about Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach.
Open access chemical and clinical probes to support drug discovery. Read more about Open access chemical and clinical probes to support drug discovery.
Structural basis for different specificities of acyltransferases associated with the human cytosolic and mitochondrial fatty acid synthases. Read more about Structural basis for different specificities of acyltransferases associated with the human cytosolic and mitochondrial fatty acid synthases.
Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors. Read more about Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors.
