Crystallization and preliminary X-ray analysis of phage Mu activator protein C in a complex with promoter DNA. Read more about Crystallization and preliminary X-ray analysis of phage Mu activator protein C in a complex with promoter DNA.
Activation segment exchange: a common mechanism of kinase autophosphorylation? Read more about Activation segment exchange: a common mechanism of kinase autophosphorylation?
Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder. Read more about Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder.
Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity. Read more about Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity.
Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases. Read more about Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases.
Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO. Read more about Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.
The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability. Read more about The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability.
Nicotinamide riboside kinase structures reveal new pathways to NAD+. Read more about Nicotinamide riboside kinase structures reveal new pathways to NAD+.
Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain. Read more about Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain.
The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins. Read more about The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins.
