The N-Myc MB0-MBI region interacts specifically and dynamically with the N-lobe of Aurora kinase A. Read more about The N-Myc MB0-MBI region interacts specifically and dynamically with the N-lobe of Aurora kinase A.
Targeting the p53 cancer mutants Y220C, Y220N, and Y220S with the small-molecule stabilizer rezatapopt. Read more about Targeting the p53 cancer mutants Y220C, Y220N, and Y220S with the small-molecule stabilizer rezatapopt.
Evaluation of non-canonical p53 functions in DNA replication and recombination for variant classification. Read more about Evaluation of non-canonical p53 functions in DNA replication and recombination for variant classification.
Novel monoclonal antibodies against the C-terminal HEAT domain of huntingtin. Read more about Novel monoclonal antibodies against the C-terminal HEAT domain of huntingtin.
USP7 deubiquitinase stabilizes FAN1 to support DNA crosslink repair and suppress CAG repeat expansion. Read more about USP7 deubiquitinase stabilizes FAN1 to support DNA crosslink repair and suppress CAG repeat expansion.
Identification and optimization of first-in-class RNA helicase inhibitors of DDX1, LGP2, and MDA5. Read more about Identification and optimization of first-in-class RNA helicase inhibitors of DDX1, LGP2, and MDA5.
Structure-Based Discovery of Selective Vaccinia-Related Kinase 1 Inhibitors and Fluorogenic Active-Site Probes. Read more about Structure-Based Discovery of Selective Vaccinia-Related Kinase 1 Inhibitors and Fluorogenic Active-Site Probes.
Evaluation of ensilication technology for ambient DNA preservation. Read more about Evaluation of ensilication technology for ambient DNA preservation.
Screening assay to monitor mono-ADP-ribosylhydrolase activity of viral macrodomains in cells. Read more about Screening assay to monitor mono-ADP-ribosylhydrolase activity of viral macrodomains in cells.
