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A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival.

  • Read more about A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival.

Structure and function of a G-actin sequestering protein with a vital role in malaria oocyst development inside the mosquito vector.

  • Read more about Structure and function of a G-actin sequestering protein with a vital role in malaria oocyst development inside the mosquito vector.

Structural biology of human H3K9 methyltransferases.

  • Read more about Structural biology of human H3K9 methyltransferases.

Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches.

  • Read more about Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches.

Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888.

  • Read more about Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888.

A miniaturized screen for inhibitors of Jumonji histone demethylases.

  • Read more about A miniaturized screen for inhibitors of Jumonji histone demethylases.

Toward a unified nomenclature for mammalian ADP-ribosyltransferases.

  • Read more about Toward a unified nomenclature for mammalian ADP-ribosyltransferases.

Pharmacophore screening of the protein data bank for specific binding site chemistry.

  • Read more about Pharmacophore screening of the protein data bank for specific binding site chemistry.

A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation.

  • Read more about A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation.

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers.

  • Read more about PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers.

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