Crystal structures of the catalytic domain of human soluble guanylate cyclase. Read more about Crystal structures of the catalytic domain of human soluble guanylate cyclase.
Optimization of 3,5-dimethylisoxazole derivatives as potent BET bromodomain ligands. Read more about Optimization of 3,5-dimethylisoxazole derivatives as potent BET bromodomain ligands.
The structural basis of ZMPSTE24-dependent laminopathies. Read more about The structural basis of ZMPSTE24-dependent laminopathies.
Development of an ALK2-Biased BMP Type I Receptor Kinase Inhibitor. Read more about Development of an ALK2-Biased BMP Type I Receptor Kinase Inhibitor.
Construction of human activity-based phosphorylation networks. Read more about Construction of human activity-based phosphorylation networks.
Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N-substituted pantothenamides. Read more about Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N-substituted pantothenamides.
Why is epigenetics important in understanding the pathogenesis of inflammatory musculoskeletal diseases? Read more about Why is epigenetics important in understanding the pathogenesis of inflammatory musculoskeletal diseases?
Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation. Read more about Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation.
PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains. Read more about PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains.
An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1. Read more about An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1.