Why is epigenetics important in understanding the pathogenesis of inflammatory musculoskeletal diseases? Read more about Why is epigenetics important in understanding the pathogenesis of inflammatory musculoskeletal diseases?
Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation. Read more about Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation.
PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains. Read more about PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains.
An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1. Read more about An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1.
Selective Bisubstrate Inhibitors with Sub-nanomolar Affinity for Protein Kinase Pim-1. Read more about Selective Bisubstrate Inhibitors with Sub-nanomolar Affinity for Protein Kinase Pim-1.
Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP. Read more about Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP.
A New Class of Small Molecule Inhibitor of BMP Signaling. Read more about A New Class of Small Molecule Inhibitor of BMP Signaling.
X-ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor. Read more about X-ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor.
Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition. Read more about Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition.
Homozygous mutations in a predicted endonuclease cause Congenital Dyserythropoietic Anemia Type I. Read more about Homozygous mutations in a predicted endonuclease cause Congenital Dyserythropoietic Anemia Type I.
