Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Read more about Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors.
Nahuoic Acid A Produced by a Streptomyces sp. Isolated From a Marine Sediment Is a Selective SAM-Competitive Inhibitor of the Histone Methyltransferase SETD8. Read more about Nahuoic Acid A Produced by a Streptomyces sp. Isolated From a Marine Sediment Is a Selective SAM-Competitive Inhibitor of the Histone Methyltransferase SETD8.
(R)-β-lysine modified elongation factor P functions in translation elongation. Read more about (R)-β-lysine modified elongation factor P functions in translation elongation.
Crystal Structure of the Human SUV39H1 Chromodomain and Its Recognition of Histone H3K9me2/3. Read more about Crystal Structure of the Human SUV39H1 Chromodomain and Its Recognition of Histone H3K9me2/3.
A Strategy for Modulation of Enzymes in the Ubiquitin System. Read more about A Strategy for Modulation of Enzymes in the Ubiquitin System.
Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain. Read more about Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain.
Structural Insights into the Activation of MST3 by MO25. Read more about Structural Insights into the Activation of MST3 by MO25.
Solution structure of the Big domain from Streptococcus pneumoniae reveals a novel Ca2+-binding module. Read more about Solution structure of the Big domain from Streptococcus pneumoniae reveals a novel Ca2+-binding module.
Novel Inverse Binding Mode of Indirubin Derivatives Yields Improved Selectivity for DYRK Kinases. Read more about Novel Inverse Binding Mode of Indirubin Derivatives Yields Improved Selectivity for DYRK Kinases.
