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Structural Insights into the Activation of MST3 by MO25.

  • Read more about Structural Insights into the Activation of MST3 by MO25.

LRIG2 Mutations Cause Urofacial Syndrome.

  • Read more about LRIG2 Mutations Cause Urofacial Syndrome.

Solution structure of the Big domain from Streptococcus pneumoniae reveals a novel Ca2+-binding module.

  • Read more about Solution structure of the Big domain from Streptococcus pneumoniae reveals a novel Ca2+-binding module.

Novel Inverse Binding Mode of Indirubin Derivatives Yields Improved Selectivity for DYRK Kinases.

  • Read more about Novel Inverse Binding Mode of Indirubin Derivatives Yields Improved Selectivity for DYRK Kinases.

Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases.

  • Read more about Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases.

A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells.

  • Read more about A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells.

Inhibition of BET Bromodomain Targets Genetically Diverse Glioblastoma.

  • Read more about Inhibition of BET Bromodomain Targets Genetically Diverse Glioblastoma.

Strategy to Target the Substrate Binding site of SET Domain Protein Methyltransferases.

  • Read more about Strategy to Target the Substrate Binding site of SET Domain Protein Methyltransferases.

A structural mapping of mutations causing succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency.

  • Read more about A structural mapping of mutations causing succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency.

Insight into S-adenosyl-L-methionine biosynthesis from crystal structures of human methionine adenosyltransferase catalytic and regulatory subunits.

  • Read more about Insight into S-adenosyl-L-methionine biosynthesis from crystal structures of human methionine adenosyltransferase catalytic and regulatory subunits.

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