Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases. Read more about Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases.
A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells. Read more about A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells.
Inhibition of BET Bromodomain Targets Genetically Diverse Glioblastoma. Read more about Inhibition of BET Bromodomain Targets Genetically Diverse Glioblastoma.
Strategy to Target the Substrate Binding site of SET Domain Protein Methyltransferases. Read more about Strategy to Target the Substrate Binding site of SET Domain Protein Methyltransferases.
A structural mapping of mutations causing succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency. Read more about A structural mapping of mutations causing succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency.
Insight into S-adenosyl-L-methionine biosynthesis from crystal structures of human methionine adenosyltransferase catalytic and regulatory subunits. Read more about Insight into S-adenosyl-L-methionine biosynthesis from crystal structures of human methionine adenosyltransferase catalytic and regulatory subunits.
Bromo-deaza-SAH: A potent and selective DOT1L inhibitor. Read more about Bromo-deaza-SAH: A potent and selective DOT1L inhibitor.
Exploiting an Allosteric Binding Site of PRMT3 Yields Potent and Selective Inhibitors. Read more about Exploiting an Allosteric Binding Site of PRMT3 Yields Potent and Selective Inhibitors.
High-throughput structural characterisation of therapeutic protein targets. Read more about High-throughput structural characterisation of therapeutic protein targets.
Systems approaches to genomic and epigenetic inter-regulation of peptide hormones in stress and reproduction. Read more about Systems approaches to genomic and epigenetic inter-regulation of peptide hormones in stress and reproduction.
