Mutations in multidomain protein MEGF8 identify a Carpenter syndrome subtype associated with defective lateralization. Read more about Mutations in multidomain protein MEGF8 identify a Carpenter syndrome subtype associated with defective lateralization.
A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B. Read more about A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B.
Bromodomain-containing Protein 4 (BRD4) Regulates RNA Polymerase II Serine 2 Phosphorylation in Human CD4+ T Cells. Read more about Bromodomain-containing Protein 4 (BRD4) Regulates RNA Polymerase II Serine 2 Phosphorylation in Human CD4+ T Cells.
Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit. Read more about Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit.
Structural insights into the inactive subunit of the apicoplast-localized caseinolytic protease complex of Plasmodium falciparum. Read more about Structural insights into the inactive subunit of the apicoplast-localized caseinolytic protease complex of Plasmodium falciparum.
Epigallocatechin-3-gallate up-regulates tumor suppressor gene expression via a reactive oxygen species-dependent down-regulation of UHRF1. Read more about Epigallocatechin-3-gallate up-regulates tumor suppressor gene expression via a reactive oxygen species-dependent down-regulation of UHRF1.
Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development. Read more about Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development.
CDR-H3 Diversity Is Not Required for Antigen Recognition by Synthetic Antibodies. Read more about CDR-H3 Diversity Is Not Required for Antigen Recognition by Synthetic Antibodies.
Tudor domains of the PRC2 components PHF1 and PHF19 selectively bind to histone H3K36me3. Read more about Tudor domains of the PRC2 components PHF1 and PHF19 selectively bind to histone H3K36me3.
A public-private partnership to unlock the untargeted kinome. Read more about A public-private partnership to unlock the untargeted kinome.
