Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family. Read more about Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family.
Druggability of methyl-lysine binding sites. Read more about Druggability of methyl-lysine binding sites.
Structural and functional insights into the DNA replication factor Cdc45 reveal an evolutionary relationship to the DHH family of phosphoesterases. Read more about Structural and functional insights into the DNA replication factor Cdc45 reveal an evolutionary relationship to the DHH family of phosphoesterases.
Conformational plasticity of glycogenin and its maltosaccharide substrate during glycogen biogenesis. Read more about Conformational plasticity of glycogenin and its maltosaccharide substrate during glycogen biogenesis.
Structural insights into the allosteric effects of 4EBP1 on the eukaryotic translation initiation factor eIF4E. Read more about Structural insights into the allosteric effects of 4EBP1 on the eukaryotic translation initiation factor eIF4E.
Recombinant protein quality evaluation: proposal for a minimal information standard. Read more about Recombinant protein quality evaluation: proposal for a minimal information standard.
Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases. Read more about Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases.
Crystal structures of the coil 2B fragment and the globular tail domain of human lamin B1. Read more about Crystal structures of the coil 2B fragment and the globular tail domain of human lamin B1.
Two ZnF-UBP domains in isopeptidase T (USP5). Read more about Two ZnF-UBP domains in isopeptidase T (USP5).
Biochemical discrimination between selenium and sulfur 1: a single residue provides selenium specificity to human selenocysteine lyase. Read more about Biochemical discrimination between selenium and sulfur 1: a single residue provides selenium specificity to human selenocysteine lyase.
