Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations. Read more about Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations.
Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor Specificity. Read more about Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor Specificity.
Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2. Read more about Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2.
Structure of Cyclin G associated kinase (GAK) Trapped in different Conformations using Nanobodies. Read more about Structure of Cyclin G associated kinase (GAK) Trapped in different Conformations using Nanobodies.
Leri's pleonosteosis, a congenital rheumatic disease, results from microduplication at 8q22.1 encompassing GDF6 and SDC2 and provides insight into systemic sclerosis pathogenesis. Read more about Leri's pleonosteosis, a congenital rheumatic disease, results from microduplication at 8q22.1 encompassing GDF6 and SDC2 and provides insight into systemic sclerosis pathogenesis.
A Chemical Tool for In Vitro and In Vivo Precipitation of Lysine Methyltransferase G9a. Read more about A Chemical Tool for In Vitro and In Vivo Precipitation of Lysine Methyltransferase G9a.
New strategies to inhibit KEAP1 and the Cul3-based E3 ubiquitin ligases. Read more about New strategies to inhibit KEAP1 and the Cul3-based E3 ubiquitin ligases.
Structures of soluble guanylate cyclase: implications for regulatory mechanisms and drug development. Read more about Structures of soluble guanylate cyclase: implications for regulatory mechanisms and drug development.
Recent advances in the structural molecular biology of Ets transcription factors: interactions, interfaces and inhibition. Read more about Recent advances in the structural molecular biology of Ets transcription factors: interactions, interfaces and inhibition.
The Structural Basis of PI3K Cancer Mutations: From Mechanism to Therapy. Read more about The Structural Basis of PI3K Cancer Mutations: From Mechanism to Therapy.
