Maintenance of muscle myosin levels in adult C. elegans requires both the double bromodomain protein BET-1 and sumoylation. Read more about Maintenance of muscle myosin levels in adult C. elegans requires both the double bromodomain protein BET-1 and sumoylation.
Targeting low-druggability bromodomains: Fragment based screening and inhibitor design against the BAZ2B bromodomain. Read more about Targeting low-druggability bromodomains: Fragment based screening and inhibitor design against the BAZ2B bromodomain.
A versatile spectrophotometric protein tyrosine phosphatase assay based on 3-nitrophosphotyrosine containing substrates. Read more about A versatile spectrophotometric protein tyrosine phosphatase assay based on 3-nitrophosphotyrosine containing substrates.
[1,2,4]Triazolo[4,3-a]phthalazines: inhibitors of diverse bromodomains. Read more about [1,2,4]Triazolo[4,3-a]phthalazines: inhibitors of diverse bromodomains.
Diverse Levels of Sequence Selectivity and Catalytic Efficiency of Protein-Tyrosine Phosphatases. Read more about Diverse Levels of Sequence Selectivity and Catalytic Efficiency of Protein-Tyrosine Phosphatases.
Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations. Read more about Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations.
Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor Specificity. Read more about Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor Specificity.
Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2. Read more about Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2.
Structure of Cyclin G associated kinase (GAK) Trapped in different Conformations using Nanobodies. Read more about Structure of Cyclin G associated kinase (GAK) Trapped in different Conformations using Nanobodies.
