Structural and biochemical characterisation of the KLHL3-WNK kinase interaction important in blood pressure regulation. Read more about Structural and biochemical characterisation of the KLHL3-WNK kinase interaction important in blood pressure regulation.
Protein ISGylation delays but does not overcome coronavirus proliferation in a model of fulminant hepatitis. Read more about Protein ISGylation delays but does not overcome coronavirus proliferation in a model of fulminant hepatitis.
Novel approaches for targeting kinases: allosteric inhibition, allosteric activation and pseudokinases. Read more about Novel approaches for targeting kinases: allosteric inhibition, allosteric activation and pseudokinases.
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy. Read more about Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.
Enzymatic and Structural Characterization of rTSγ Provides Insights into the Function of rTSβ. Read more about Enzymatic and Structural Characterization of rTSγ Provides Insights into the Function of rTSβ.
Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases. Read more about Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases.
Epigenetic targets and drug discovery: Part 1: Histone methylation. Read more about Epigenetic targets and drug discovery: Part 1: Histone methylation.
Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma. Read more about Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma.
Copper is required for oncogenic BRAF signalling and tumorigenesis. Read more about Copper is required for oncogenic BRAF signalling and tumorigenesis.
Exploration of Type II Binding Mode: A Privileged Approach for Kinase Inhibitor Focused Drug Discovery? Read more about Exploration of Type II Binding Mode: A Privileged Approach for Kinase Inhibitor Focused Drug Discovery?
