A structural mapping of mutations causing succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency. Read more about A structural mapping of mutations causing succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency.
Insight into S-adenosyl-L-methionine biosynthesis from crystal structures of human methionine adenosyltransferase catalytic and regulatory subunits. Read more about Insight into S-adenosyl-L-methionine biosynthesis from crystal structures of human methionine adenosyltransferase catalytic and regulatory subunits.
Bromo-deaza-SAH: A potent and selective DOT1L inhibitor. Read more about Bromo-deaza-SAH: A potent and selective DOT1L inhibitor.
Exploiting an Allosteric Binding Site of PRMT3 Yields Potent and Selective Inhibitors. Read more about Exploiting an Allosteric Binding Site of PRMT3 Yields Potent and Selective Inhibitors.
High-throughput structural characterisation of therapeutic protein targets. Read more about High-throughput structural characterisation of therapeutic protein targets.
Systems approaches to genomic and epigenetic inter-regulation of peptide hormones in stress and reproduction. Read more about Systems approaches to genomic and epigenetic inter-regulation of peptide hormones in stress and reproduction.
Crystal structures of the catalytic domain of human soluble guanylate cyclase. Read more about Crystal structures of the catalytic domain of human soluble guanylate cyclase.
Optimization of 3,5-dimethylisoxazole derivatives as potent BET bromodomain ligands. Read more about Optimization of 3,5-dimethylisoxazole derivatives as potent BET bromodomain ligands.
The structural basis of ZMPSTE24-dependent laminopathies. Read more about The structural basis of ZMPSTE24-dependent laminopathies.
Development of an ALK2-Biased BMP Type I Receptor Kinase Inhibitor. Read more about Development of an ALK2-Biased BMP Type I Receptor Kinase Inhibitor.
