Control of the Hippo Pathway by Set7-Dependent Methylation of Yap. Read more about Control of the Hippo Pathway by Set7-Dependent Methylation of Yap.
Topical anti-angiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative-AMD. Read more about Topical anti-angiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative-AMD.
Discovery of a Potent and Selective DDR1 Receptor Tyrosine Kinase Inhibitor. Read more about Discovery of a Potent and Selective DDR1 Receptor Tyrosine Kinase Inhibitor.
Testis specific gene expression drives disease progression and Rituximab resistance in lymphoma. Read more about Testis specific gene expression drives disease progression and Rituximab resistance in lymphoma.
Suppressor of Cytokine Signaling (SOCS) 5 Utilises Distinct Domains for Regulation of JAK1 and Interaction with the Adaptor Protein Shc-1. Read more about Suppressor of Cytokine Signaling (SOCS) 5 Utilises Distinct Domains for Regulation of JAK1 and Interaction with the Adaptor Protein Shc-1.
Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase. Read more about Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase.
Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1. Read more about Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1.
Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases. Read more about Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases.
Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation. Read more about Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation.
Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening. Read more about Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening.
