Modulation of the chromatin phosphoproteome by the Haspin protein kinase. Read more about Modulation of the chromatin phosphoproteome by the Haspin protein kinase.
Targeting bromodomains: epigenetic readers of lysine acetylation. Read more about Targeting bromodomains: epigenetic readers of lysine acetylation.
Structural Mechanisms Determining Inhibition of the Collagen Receptor DDR1 by Selective and Multi-Targeted Type II Kinase Inhibitors. Read more about Structural Mechanisms Determining Inhibition of the Collagen Receptor DDR1 by Selective and Multi-Targeted Type II Kinase Inhibitors.
Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single stranded m6A RNA demethylation. Read more about Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single stranded m6A RNA demethylation.
Human UTY(KDM6C) is a Male-Specific N{epsilon}-Methyl Lysyl-Demethylase. Read more about Human UTY(KDM6C) is a Male-Specific N{epsilon}-Methyl Lysyl-Demethylase.
A Chromatin-Dependent Role of the Fragile X Mental Retardation Protein FMRP in the DNA Damage Response. Read more about A Chromatin-Dependent Role of the Fragile X Mental Retardation Protein FMRP in the DNA Damage Response.
Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Read more about Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced-Fit Pocket Stabilized by a Cation-π Interaction. Read more about A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced-Fit Pocket Stabilized by a Cation-π Interaction.
Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1. Read more about Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.
Multiparameter Optimization in CNS Drug Discovery: Design of Pyrimido[4,5-d]azepines as Potent 5-Hydroxytryptamine 2C (5-HT2C) Receptor Agonists with Exquisite Functional Selectivity over 5-HT2A and 5-HT2B Receptors. Read more about Multiparameter Optimization in CNS Drug Discovery: Design of Pyrimido[4,5-d]azepines as Potent 5-Hydroxytryptamine 2C (5-HT2C) Receptor Agonists with Exquisite Functional Selectivity over 5-HT2A and 5-HT2B Receptors.
