News from SGC

Posted on Thursday 21st of January 2016
This SRC is focused on the role of Methylation Dynamics in nuclear and cytoplasmic biological processes and how this modification impacts development, epigenetic cellular identity, tissue homeostasis and disease.
Posted on Tuesday 12th of January 2016

During DPhG Annual Meeting 2015 which took place in Düsseldorf September 23-25, 2015, the German Pharmaceutical Society honoured a few up-and-coming young scientists.

Posted on Wednesday 16th of December 2015

University of Toronto and McGill University scientists are leading an international partnership to discover new and improved drug treatments for tuberculosis, malaria and neglected tropical diseases -- thanks to a contribution from Merck Canada Inc., as well as an additional $5 million supplement to a grant from the Bill & Melinda Gates Foundation. The new funding brings the total investment from the Bill & Melinda Gates Foundation to nearly US $12 million since 2012.

Posted on Friday 4th of December 2015

Takeda Pharmaceutical Company Limited (Takeda) today announced it has renewed its partnership with the Structural Genomics Consortium (SGC) to fund collective drug research aimed at bringing new, more effective medicines to patients faster.

Posted on Monday 23rd of November 2015

SGC-Toronto's Chief Scientist, Dr.

Posted on Thursday 19th of November 2015

MONTREAL, Nov. 18, 2015 /CNW/ - AbbVie today announced its continued commitment to the Structural Genomics Consortium (SGC) by providing a cash sponsorship of CDA$7.5 million towards open access research leading to the discovery of new medicines. Today`s announcement coincides with meetings with Ontario and Quebec-based research leaders and AbbVie global research and development business development professionals to assess continued investment. 

Posted on Wednesday 11th of November 2015

Ponatinib is an anti-cancer drug which has earned some notoriety for its cost (£90,000 per patient per year) and side-effects that were serious enough to temporarily suspend its use. But the findings from a recent Cell Chemistry and Biology paper led by the Structural Genomics Consortium suggest that this 'dirty' drug might actually hold the key for coming up with newer, more effective drugs for chronic illnesses such as Crohn's and Inflammatory Bowel Disease. The Oxford Science Blog asked the first author, Dr Peter Canning (who worked on this study while at the Nuffield Department of Medicine) to explain what they found.

Posted on Wednesday 28th of October 2015

The SGC is engaged in dozens of collaborations with small companies to explore novel technologies.  In keeping with the SGC’s open-access policy,  all outputs from these collaboration are made publicly available without restriction on use.  As announced today, the SGC in Oxford is collaborating with C4X to discover chemical tools for epigenetic targets.  C4X will use its unique ligand conformation analysis technology to design potent inhibitors that will be tested at the SGC and rapidly made available to the public. 

Posted on Monday 21st of September 2015
Ellie Williams has won the poster prize for the Biochemical Society's 78th Harden Conference: Protein Kinases in Health and Disease. She presented the recent work she and her colleagues have done investigating a pre-clinical compound (K04284) that may have applications in the rare disease Fibrodisplasia Ossificans Progressiva (FOP). FOP is caused by a single point mutation in the ALK2 kinase leading to uncontrolled bone formation and there is currently no treatment. K04284 is already in Phase 2 clinical trials for the treatment of some cancers and its additional activity against ALK2 provides exciting potential for fast track clinical trials for FOP.
Posted on Thursday 3rd of September 2015

Through a novel open source approach the molecule has been made freely available to the cancer research community to help discover new therapeutic strategies for cancer patients sooner.


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