News from SGC

Posted on Wednesday 7th of May 2014

The Group led by Professor Chas Bountra, Chief Scientist of SGC Oxford, has been awarded the Royal Society of Chemistry's Rita and John Cornforth Award 2014 for "... world leading collaborative research across the disciplines of structural biology, medicinal chemistry, chemical biology and enzymology towards understanding and exploiting the potential of epigenetics as a target family for future drug discovery". 

Posted on Tuesday 22nd of April 2014

Inhibiting bromodomains - which are small interaction modules on proteins that assemble acetylation-dependent transcriptional regulatory complexes - could be a way to alter the expression of disease-promoting genes. In a Nature Reviews Drug Discovery article, the SGC highlights recent developments in the discovery of small-molecule bromodomain inhibitors and discuss how they might be used in cancer, inflammation and viral infection.

Posted on Tuesday 25th of February 2014
The Structural Genomics Consortium (SGC) and DiscoveRx Corporation announced the publication of findings demonstrating that several clinical kinase inhibitors also potently inhibit diverse bromodomain epigenetic reader proteins. This study titled “Dual kinase-bromodomain inhibitors for rationally designed polypharmacology”, which appears on-line today in Nature Chemical Biology , suggests compelling new multi-targeting approaches for cancer therapy.
Posted on Thursday 19th of December 2013
Bayer Inc. is pleased to announce that Bayer HealthCare has joined the SGC, a not-for-profit, public-private partnership with active research facilities at the Universities of Toronto and Oxford, UK.
Posted on Tuesday 26th of November 2013
The Open Access nature of SGC work is discussed in this article on
Posted on Sunday 27th of October 2013
The Structural Genomics Consortium (SGC) announced today that Janssen Pharmaceuticals NV has joined its group to partner in the investigation of epigenetics-based drug research, a new and burgeoning field in the development of future medicines.
Posted on Sunday 27th of October 2013
The SGC's Prof. Chas Bountra interviewed for the University of Oxford website. [article].
Posted on Friday 9th of August 2013
Today we learned the sad news that Tony Pawson, a former member of the SGC Scientific Committee, and a friend and colleague of many SGC scientists, died this week. He was a fantastic person, scientist and collaborator.


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