Structure of LRRK1 and mechanisms of autoinhibition and activation. Read more about Structure of LRRK1 and mechanisms of autoinhibition and activation.
Methods for computer-assisted PROTAC design. Read more about Methods for computer-assisted PROTAC design.
Identification of high-performing antibodies for Superoxide dismutase [Cu-Zn] 1 (SOD1) for use in Western blot, immunoprecipitation, and immunofluorescence. Read more about Identification of high-performing antibodies for Superoxide dismutase [Cu-Zn] 1 (SOD1) for use in Western blot, immunoprecipitation, and immunofluorescence.
Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. Read more about Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
Wnt/β-catenin and NFκB signaling synergize to trigger growth-factor-free regeneration of adult primary human hepatocytes. Read more about Wnt/β-catenin and NFκB signaling synergize to trigger growth-factor-free regeneration of adult primary human hepatocytes.
Dual Inhibition of Mycobacterium tuberculosis and the Host TGFBR1 by an Anilinoquinazoline. Read more about Dual Inhibition of Mycobacterium tuberculosis and the Host TGFBR1 by an Anilinoquinazoline.
Fused Tetrahydroquinolines Are Interfering with Your Assay. Read more about Fused Tetrahydroquinolines Are Interfering with Your Assay.
Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5-a]pyrimidines toward the Development of an In Vivo Chemical Probe for CSNK2A. Read more about Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5-a]pyrimidines toward the Development of an In Vivo Chemical Probe for CSNK2A.
Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors. Read more about Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors.
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors. Read more about Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.
