Synthesis of 5-Benzylamino and 5-Alkylamino-Substituted Pyrimido[4,5-c]quinoline Derivatives as CSNK2A Inhibitors with Antiviral Activity. Read more about Synthesis of 5-Benzylamino and 5-Alkylamino-Substituted Pyrimido[4,5-c]quinoline Derivatives as CSNK2A Inhibitors with Antiviral Activity.
A guide to selecting high-performing antibodies for Rab1A and Rab1B for use in Western Blot, immunoprecipitation and immunofluorescence. Read more about A guide to selecting high-performing antibodies for Rab1A and Rab1B for use in Western Blot, immunoprecipitation and immunofluorescence.
Loss-of-function mutation in PRMT9 causes abnormal synapse development by dysregulation of RNA alternative splicing. Read more about Loss-of-function mutation in PRMT9 causes abnormal synapse development by dysregulation of RNA alternative splicing.
Identification and structural characterization of small molecule inhibitors of PINK1. Read more about Identification and structural characterization of small molecule inhibitors of PINK1.
MITOCHONDRIAL IMPORT STRESS and PINK1-MEDIATED MITOPHAGY: THE ROLE of the PINK1-TOMM-TIMM23 SUPERCOMPLEX. Read more about MITOCHONDRIAL IMPORT STRESS and PINK1-MEDIATED MITOPHAGY: THE ROLE of the PINK1-TOMM-TIMM23 SUPERCOMPLEX.
Emerging structure-based computational methods to screen the exploding accessible chemical space. Read more about Emerging structure-based computational methods to screen the exploding accessible chemical space.
Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on SNAr Electrophiles. Read more about Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on SNAr Electrophiles.
Expanding the ligand spaces for E3 ligases for the design of protein degraders. Read more about Expanding the ligand spaces for E3 ligases for the design of protein degraders.
Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships. Read more about Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships.
Luciferase- and HaloTag-based reporter assays to measure small-molecule-induced degradation pathway in living cells. Read more about Luciferase- and HaloTag-based reporter assays to measure small-molecule-induced degradation pathway in living cells.
