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Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator.

  • Read more about Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator.

Structure-guided drug discovery: back to the future.

  • Read more about Structure-guided drug discovery: back to the future.

Discovery of Conformationally Constrained ALK2 Inhibitors.

  • Read more about Discovery of Conformationally Constrained ALK2 Inhibitors.

Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex.

  • Read more about Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex.

Illumination of understudied ciliary kinases.

  • Read more about Illumination of understudied ciliary kinases.

Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor.

  • Read more about Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor.

Synthesis of 5-Benzylamino and 5-Alkylamino-Substituted Pyrimido[4,5-c]quinoline Derivatives as CSNK2A Inhibitors with Antiviral Activity.

  • Read more about Synthesis of 5-Benzylamino and 5-Alkylamino-Substituted Pyrimido[4,5-c]quinoline Derivatives as CSNK2A Inhibitors with Antiviral Activity.

A guide to selecting high-performing antibodies for Rab1A and Rab1B for use in Western Blot, immunoprecipitation and immunofluorescence.

  • Read more about A guide to selecting high-performing antibodies for Rab1A and Rab1B for use in Western Blot, immunoprecipitation and immunofluorescence.

Loss-of-function mutation in PRMT9 causes abnormal synapse development by dysregulation of RNA alternative splicing.

  • Read more about Loss-of-function mutation in PRMT9 causes abnormal synapse development by dysregulation of RNA alternative splicing.

Identification and structural characterization of small molecule inhibitors of PINK1.

  • Read more about Identification and structural characterization of small molecule inhibitors of PINK1.

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