MITOCHONDRIAL IMPORT STRESS and PINK1-MEDIATED MITOPHAGY: THE ROLE of the PINK1-TOMM-TIMM23 SUPERCOMPLEX. Read more about MITOCHONDRIAL IMPORT STRESS and PINK1-MEDIATED MITOPHAGY: THE ROLE of the PINK1-TOMM-TIMM23 SUPERCOMPLEX.
Emerging structure-based computational methods to screen the exploding accessible chemical space. Read more about Emerging structure-based computational methods to screen the exploding accessible chemical space.
Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on SNAr Electrophiles. Read more about Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on SNAr Electrophiles.
Expanding the ligand spaces for E3 ligases for the design of protein degraders. Read more about Expanding the ligand spaces for E3 ligases for the design of protein degraders.
Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships. Read more about Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships.
Luciferase- and HaloTag-based reporter assays to measure small-molecule-induced degradation pathway in living cells. Read more about Luciferase- and HaloTag-based reporter assays to measure small-molecule-induced degradation pathway in living cells.
A guide to selecting high-performing antibodies for RNA-binding protein TIA1 for use in Western Blot, immunoprecipitation and immunofluorescence. Read more about A guide to selecting high-performing antibodies for RNA-binding protein TIA1 for use in Western Blot, immunoprecipitation and immunofluorescence.
Probing the CRL4DCAF12 interactions with MAGEA3 and CCT5 di-Glu C-terminal degrons. Read more about Probing the CRL4DCAF12 interactions with MAGEA3 and CCT5 di-Glu C-terminal degrons.
Tetrahydropyridine LIMK inhibitors: Structure activity studies and biological characterization. Read more about Tetrahydropyridine LIMK inhibitors: Structure activity studies and biological characterization.
Development of Peptide Displacement Assays to Screen for Antagonists of DDB1 Interactions. Read more about Development of Peptide Displacement Assays to Screen for Antagonists of DDB1 Interactions.
