A chemical probe to modulate human GID4 Pro/N-degron interactions. Read more about A chemical probe to modulate human GID4 Pro/N-degron interactions.
Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε. Read more about Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε.
Splice variants of CK1α and CK1α-like: Comparative analysis of subcellular localization, kinase activity and function in the Wnt signaling pathway. Read more about Splice variants of CK1α and CK1α-like: Comparative analysis of subcellular localization, kinase activity and function in the Wnt signaling pathway.
Structural basis for inhibition of the lysosomal two-pore channel TPC2 by a small molecule antagonist. Read more about Structural basis for inhibition of the lysosomal two-pore channel TPC2 by a small molecule antagonist.
Anti-FHL1 autoantibodies in adult patients with myositis: a longitudinal follow-up analysis. Read more about Anti-FHL1 autoantibodies in adult patients with myositis: a longitudinal follow-up analysis.
The Pan-Canadian Chemical Library: A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening. Read more about The Pan-Canadian Chemical Library: A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening.
Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators. Read more about Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators.
A designed ankyrin-repeat protein that targets Parkinson's disease-associated LRRK2. Read more about A designed ankyrin-repeat protein that targets Parkinson's disease-associated LRRK2.
Subpocket Similarity-Based Hit Identification for Challenging Targets: Application to the WDR Domain of LRRK2. Read more about Subpocket Similarity-Based Hit Identification for Challenging Targets: Application to the WDR Domain of LRRK2.
