Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors. Read more about Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors.
A ligand discovery toolbox for the WWE domain family of human E3 ligases. Read more about A ligand discovery toolbox for the WWE domain family of human E3 ligases.
Identification of Dihydropyrazolo[1,5-a]pyrazin-4(5H)-ones as Cyclic Products of β-Amidomethyl Vinyl Sulfone Alphavirus Cysteine Protease Inhibitors. Read more about Identification of Dihydropyrazolo[1,5-a]pyrazin-4(5H)-ones as Cyclic Products of β-Amidomethyl Vinyl Sulfone Alphavirus Cysteine Protease Inhibitors.
Synthesis and evaluation of chemical linchpins for highly selective CK2α targeting. Read more about Synthesis and evaluation of chemical linchpins for highly selective CK2α targeting.
Quantitative Hydrogen-Deuterium Exchange Mass Spectrometry for Simultaneous Structural Characterization and Affinity Indexing of Single Target Drug Candidate Libraries. Read more about Quantitative Hydrogen-Deuterium Exchange Mass Spectrometry for Simultaneous Structural Characterization and Affinity Indexing of Single Target Drug Candidate Libraries.
Benchmarking Methods for PROTAC Ternary Complex Structure Prediction. Read more about Benchmarking Methods for PROTAC Ternary Complex Structure Prediction.
A guide to selecting high-performing antibodies for human Midkine for use in Western blot and immunoprecipitation. Read more about A guide to selecting high-performing antibodies for human Midkine for use in Western blot and immunoprecipitation.
High-Throughput Screening for LC3/GABARAP Binders Utilizing the Fluorescence Polarization Assay. Read more about High-Throughput Screening for LC3/GABARAP Binders Utilizing the Fluorescence Polarization Assay.
Thermodynamic Characterization of LC3/GABARAP:Ligand Interactions by Isothermal Titration Calorimetry. Read more about Thermodynamic Characterization of LC3/GABARAP:Ligand Interactions by Isothermal Titration Calorimetry.
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2. Read more about Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2.
