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Development of a Second-Generation, In Vivo Chemical Probe for PIKfyve.

  • Read more about Development of a Second-Generation, In Vivo Chemical Probe for PIKfyve.

Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity.

  • Read more about Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity.

A Covalent Chemical Probe for Chikungunya nsP2 Cysteine Protease with Antialphaviral Activity and Proteome-wide Selectivity.

  • Read more about A Covalent Chemical Probe for Chikungunya nsP2 Cysteine Protease with Antialphaviral Activity and Proteome-wide Selectivity.

Probe my Pathway (PmP): a portal to explore the chemical coverage of the human Reactome.

  • Read more about Probe my Pathway (PmP): a portal to explore the chemical coverage of the human Reactome.

Screening of a kinase inhibitor library identified novel targetable kinase pathways in triple-negative breast cancer.

  • Read more about Screening of a kinase inhibitor library identified novel targetable kinase pathways in triple-negative breast cancer.

Design, Synthesis, and Biochemical Evaluation of Novel MLK3 Inhibitors: A Target Hopping Example.

  • Read more about Design, Synthesis, and Biochemical Evaluation of Novel MLK3 Inhibitors: A Target Hopping Example.

A consensus platform for antibody characterization.

  • Read more about A consensus platform for antibody characterization.

DARPins as a novel tool to detect and degrade p73.

  • Read more about DARPins as a novel tool to detect and degrade p73.

Interplay between β-propeller subunits WDR26 and muskelin regulates the CTLH E3 ligase supramolecular complex.

  • Read more about Interplay between β-propeller subunits WDR26 and muskelin regulates the CTLH E3 ligase supramolecular complex.

Probing the Protein Kinases' Cysteinome by Covalent Fragments.

  • Read more about Probing the Protein Kinases' Cysteinome by Covalent Fragments.

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