Crystal structures of human CDY proteins reveal a crotonase-like fold. Read more about Crystal structures of human CDY proteins reveal a crotonase-like fold.
Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors. Read more about Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors.
Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach. Read more about Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach.
Open access chemical and clinical probes to support drug discovery. Read more about Open access chemical and clinical probes to support drug discovery.
Structural basis for different specificities of acyltransferases associated with the human cytosolic and mitochondrial fatty acid synthases. Read more about Structural basis for different specificities of acyltransferases associated with the human cytosolic and mitochondrial fatty acid synthases.
Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors. Read more about Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors.
Crystal structure of human diphosphoinositol phosphatase 1. Read more about Crystal structure of human diphosphoinositol phosphatase 1.
Propionate analogues of zearalenone bind to Hsp90. Read more about Propionate analogues of zearalenone bind to Hsp90.
Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases. Read more about Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases.
Out of the box binding determines specificity of SH2 domain interaction. Read more about Out of the box binding determines specificity of SH2 domain interaction.
