SH2 domains: modulators of nonreceptor tyrosine kinase activity. Read more about SH2 domains: modulators of nonreceptor tyrosine kinase activity.
Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteins. Read more about Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteins.
Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase. Read more about Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase.
PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA. Read more about PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA.
Crystal structure of the PHF8 Jumonji domain, an Nepsilon-methyl lysine demethylase. Read more about Crystal structure of the PHF8 Jumonji domain, an Nepsilon-methyl lysine demethylase.
Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78. Read more about Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78.
The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma. Read more about The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma.
A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival. Read more about A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival.
Structure and function of a G-actin sequestering protein with a vital role in malaria oocyst development inside the mosquito vector. Read more about Structure and function of a G-actin sequestering protein with a vital role in malaria oocyst development inside the mosquito vector.
Structural biology of human H3K9 methyltransferases. Read more about Structural biology of human H3K9 methyltransferases.
