Discovery of a potent and selective inhibitor for human carbonyl reductase 1 from propionate scanning applied to the macrolide zearalenone. Read more about Discovery of a potent and selective inhibitor for human carbonyl reductase 1 from propionate scanning applied to the macrolide zearalenone.
Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis. Read more about Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis.
Structure of the pseudokinase VRK3 reveals a degraded catalytic site, a highly conserved kinase fold, and a putative regulatory binding site. Read more about Structure of the pseudokinase VRK3 reveals a degraded catalytic site, a highly conserved kinase fold, and a putative regulatory binding site.
Discovery of indoline-based, natural-product-like compounds as probes of focal adhesion kinase signaling pathways. Read more about Discovery of indoline-based, natural-product-like compounds as probes of focal adhesion kinase signaling pathways.
Structure of the human RECQ1 helicase reveals a putative strand-separation pin. Read more about Structure of the human RECQ1 helicase reveals a putative strand-separation pin.
Targeting group II PAKs in cancer and metastasis. Read more about Targeting group II PAKs in cancer and metastasis.
Large-scale structural analysis of the classical human protein tyrosine phosphatome. Read more about Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Novel structural and regulatory features of rhoptry secretory kinases in Toxoplasma gondii. Read more about Novel structural and regulatory features of rhoptry secretory kinases in Toxoplasma gondii.
Distinguishing between calpain heterodimerization and homodimerization. Read more about Distinguishing between calpain heterodimerization and homodimerization.
Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2. Read more about Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2.
