Generating a panel of highly specific antibodies to 20 human SH2 domains by phage display. Read more about Generating a panel of highly specific antibodies to 20 human SH2 domains by phage display.
Open-access public-private partnerships to enable drug discovery--new approaches. Read more about Open-access public-private partnerships to enable drug discovery--new approaches.
Bardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signaling. Read more about Bardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signaling.
Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress. Read more about Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress.
Structural genomics-impact on biomedicine and drug discovery. Read more about Structural genomics-impact on biomedicine and drug discovery.
Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity. Read more about Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity.
Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design. Read more about Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design.
A software tool to accelerate design of protein constructs for recombinant expression. Read more about A software tool to accelerate design of protein constructs for recombinant expression.
N-myristoyltransferase inhibitors as new leads to treat sleeping sickness. Read more about N-myristoyltransferase inhibitors as new leads to treat sleeping sickness.
Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme. Read more about Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme.
