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Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design.

  • Read more about Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design.

A software tool to accelerate design of protein constructs for recombinant expression.

  • Read more about A software tool to accelerate design of protein constructs for recombinant expression.

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness.

  • Read more about N-myristoyltransferase inhibitors as new leads to treat sleeping sickness.

Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme.

  • Read more about Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme.

Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity.

  • Read more about Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity.

Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function.

  • Read more about Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function.

Probing the structural basis of RecQ helicase function.

  • Read more about Probing the structural basis of RecQ helicase function.

New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights.

  • Read more about New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights.

Mass spectrometry following mild enzymatic digestion reveals phosphorylation of recombinant proteins in Escherichia coli through mechanisms involving direct nucleotide binding.

  • Read more about Mass spectrometry following mild enzymatic digestion reveals phosphorylation of recombinant proteins in Escherichia coli through mechanisms involving direct nucleotide binding.

Classification of the short-chain dehydrogenase/reductase superfamily using hidden Markov models.

  • Read more about Classification of the short-chain dehydrogenase/reductase superfamily using hidden Markov models.

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