Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design. Read more about Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design.
A software tool to accelerate design of protein constructs for recombinant expression. Read more about A software tool to accelerate design of protein constructs for recombinant expression.
N-myristoyltransferase inhibitors as new leads to treat sleeping sickness. Read more about N-myristoyltransferase inhibitors as new leads to treat sleeping sickness.
Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme. Read more about Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme.
Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity. Read more about Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity.
Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function. Read more about Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function.
Probing the structural basis of RecQ helicase function. Read more about Probing the structural basis of RecQ helicase function.
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights. Read more about New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights.
Mass spectrometry following mild enzymatic digestion reveals phosphorylation of recombinant proteins in Escherichia coli through mechanisms involving direct nucleotide binding. Read more about Mass spectrometry following mild enzymatic digestion reveals phosphorylation of recombinant proteins in Escherichia coli through mechanisms involving direct nucleotide binding.
Classification of the short-chain dehydrogenase/reductase superfamily using hidden Markov models. Read more about Classification of the short-chain dehydrogenase/reductase superfamily using hidden Markov models.