Crystal structure of human aurora B in complex with INCENP and VX-680. Read more about Crystal structure of human aurora B in complex with INCENP and VX-680.
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis. Read more about Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.
Progress in the Development and Application of Small Molecule Inhibitors of Bromodomain-Acetyl-lysine Interactions. Read more about Progress in the Development and Application of Small Molecule Inhibitors of Bromodomain-Acetyl-lysine Interactions.
Structures of human DPP7 reveal the molecular basis of specific inhibition and the architectural diversity of proline-specific peptidases. Read more about Structures of human DPP7 reveal the molecular basis of specific inhibition and the architectural diversity of proline-specific peptidases.
Histone recognition by human malignant brain tumor domains. Read more about Histone recognition by human malignant brain tumor domains.
Structure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressiva. Read more about Structure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressiva.
Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5. Read more about Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5.
Certhrax Toxin, an Anthrax-related ADP-ribosyltransferase from Bacillus cereus. Read more about Certhrax Toxin, an Anthrax-related ADP-ribosyltransferase from Bacillus cereus.
Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B. Read more about Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.
Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation. Read more about Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation.