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Synthesis, Optimization, and Evaluation of Novel Small Molecules as Antagonists of WDR5-MLL Interaction.

  • Read more about Synthesis, Optimization, and Evaluation of Novel Small Molecules as Antagonists of WDR5-MLL Interaction.

Discovery and development of potent and selective inhibitors of histone methyltransferase g9a.

  • Read more about Discovery and development of potent and selective inhibitors of histone methyltransferase g9a.

A comparison of protein kinases inhibitor screening methods using both enzymatic activity and binding affinity determination.

  • Read more about A comparison of protein kinases inhibitor screening methods using both enzymatic activity and binding affinity determination.

STRUCTURAL CHARACTERIZATION OF HUMAN CHOLESTEROL 7α-HYDROXYLASE.

  • Read more about STRUCTURAL CHARACTERIZATION OF HUMAN CHOLESTEROL 7α-HYDROXYLASE.

Linking genotypes database with locus-specific database and genotype-phenotype correlation in phenylketonuria.

  • Read more about Linking genotypes database with locus-specific database and genotype-phenotype correlation in phenylketonuria.

Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains.

  • Read more about Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains.

Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation.

  • Read more about Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation.

RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.

  • Read more about RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.

A scintillation proximity assay for histone demethylases.

  • Read more about A scintillation proximity assay for histone demethylases.

Bromodomain Protein BRD4 Is Required for Estrogen Receptor-Dependent Enhancer Activation and Gene Transcription.

  • Read more about Bromodomain Protein BRD4 Is Required for Estrogen Receptor-Dependent Enhancer Activation and Gene Transcription.

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