Publications

You can search the extensive SGC publications list with keywords from the title, authors or journal name. Your search results can be exported to an Excel file by clicking the orange XLS button next to the search filters

2006

Carbonyl reductases: the complex relationships of mammalian carbonyl- and quinone-reducing enzymes and their role in physiology.

Oppermann U

Annu. Rev. Pharmacol. Toxicol.. 47:293-322. doi: 10.1146/annurev.pharmtox.47.120505.105316

Publication date: October 3, 2006

PMID: 17009925

Structural basis for molecular recognition and presentation of histone H3 by WDR5.

Schuetz A, Allali-Hassani A, Martín F, Loppnau P, Vedadi M, Bochkarev A, Plotnikov AN, Arrowsmith CH, Min J

EMBO J.. 25(18):4245-52. doi: 10.1038/sj.emboj.7601316

Publication date: September 20, 2006

PMID: 16946699

Crystal structures of human sulfotransferases SULT1B1 and SULT1C1 complexed with the cofactor product adenosine-3'- 5'-diphosphate (PAP).

Dombrovski L, Dong A, Bochkarev A, Plotnikov AN

Proteins. 64(4):1091-4. doi: 10.1002/prot.21048

Publication date: September 1, 2006

PMID: 16804942

MAPK-specific tyrosine phosphatases: new targets for drug discovery?

Barr AJ, Knapp S

Trends Pharmacol. Sci.. 27(10):525-30. doi: 10.1016/j.tips.2006.08.005

Publication date: August 21, 2006

PMID: 16919785

The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding.

Kavanagh KL, Dunford JE, Bunkoczi G, Russell RG, Oppermann U

J. Biol. Chem.. 281(31):22004-12. doi: 10.1074/jbc.M602603200

Publication date: August 4, 2006

PMID: 16698791

High-throughput structural characterisation of therapeutic protein targets.

Marsden BD, Sundstrom M, Knapp S

Expert Opin Drug Discov. 1(2):123-36. doi: 10.1517/17460441.1.2.123

Publication date: July 1, 2006

PMID: 23495796

Inhibition of protein-protein interactions: the discovery of druglike beta-catenin inhibitors by combining virtual and biophysical screening.

Trosset JY, Dalvit C, Knapp S, Fasolini M, Veronesi M, Mantegani S, Gianellini LM, Catana C, Sundström M, Stouten PF, Moll JK

Proteins. 64(1):60-7. doi: 10.1002/prot.20955

Publication date: July 1, 2006

PMID: 16568448

Crystal structure of human protein tyrosine phosphatase 14 (PTPN14) at 1.65-A resolution.

Barr AJ, Debreczeni JE, Eswaran J, Knapp S

Proteins. 63(4):1132-6. doi: 10.1002/prot.20958

Publication date: June 1, 2006

PMID: 16534812

Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase.

Bullock AN, Debreczeni JE, Edwards AM, Sundström M, Knapp S

Proc. Natl. Acad. Sci. U.S.A.. 103(20):7637-42. doi: 10.1073/pnas.0601638103

Publication date: May 16, 2006

PMID: 16675548

The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs.

Kavanagh KL, Guo K, Dunford JE, Wu X, Knapp S, Ebetino FH, Rogers MJ, Russell RG, Oppermann U

Proc. Natl. Acad. Sci. U.S.A.. 103(20):7829-34. doi: 10.1073/pnas.0601643103

Publication date: May 16, 2006

PMID: 16684881

The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1.

Eswaran J, Debreczeni JE, Longman E, Barr AJ, Knapp S

Protein Sci.. 15(6):1500-5. doi: 10.1110/ps.062128706

Publication date: May 2, 2006

PMID: 16672235

Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases.

Eswaran J, von Kries JP, Marsden B, Longman E, Debreczeni JE, Ugochukwu E, Turnbull A, Lee WH, Knapp S, Barr AJ

Biochem. J.. 395(3):483-91. doi: 10.1042/BJ20051931

Publication date: May 1, 2006

PMID: 16441242

Gas phase characterization of the noncovalent quaternary structure of cholera toxin and the cholera toxin B subunit pentamer.

Williams JP, Smith DC, Green BN, Marsden BD, Jennings KR, Roberts LM, Scrivens JH

Biophys. J.. 90(9):3246-54. doi: 10.1529/biophysj.105.076455

Publication date: May 1, 2006

PMID: 16461395

Characterization of human DHRS6, an orphan short chain dehydrogenase/reductase enzyme: a novel, cytosolic type 2 R-beta-hydroxybutyrate dehydrogenase.

Guo K, Lukacik P, Papagrigoriou E, Meier M, Lee WH, Adamski J, Oppermann U

J. Biol. Chem.. 281(15):10291-7. doi: 10.1074/jbc.M511346200

Publication date: April 14, 2006

PMID: 16380372

Active site variability of type 1 11beta-hydroxysteroid dehydrogenase revealed by selective inhibitors and cross-species comparisons.

Hult M, Shafqat N, Elleby B, Mitschke D, Svensson S, Forsgren M, Barf T, Vallgårda J, Abrahmsen L, Oppermann U

Mol. Cell. Endocrinol.. 248(1-2):26-33. doi: 10.1016/j.mce.2005.11.043

Publication date: March 27, 2006

PMID: 16431016

Structure and function of human 17beta-hydroxysteroid dehydrogenases.

Lukacik P, Kavanagh KL, Oppermann U

Mol. Cell. Endocrinol.. 248(1-2):61-71. doi: 10.1016/j.mce.2005.12.007

Publication date: March 27, 2006

PMID: 16414178

Ruthenium half-sandwich complexes bound to protein kinase Pim-1.

Debreczeni JE, Bullock AN, Atilla GE, Williams DS, Bregman H, Knapp S, Meggers E

Angew. Chem. Int. Ed. Engl.. 45(10):1580-5. doi: 10.1002/anie.200503468

Publication date: February 27, 2006

PMID: 16381041

Disseminating structural genomics data to the public: from a data dump to an animated story.

Abagyan R, Lee WH, Raush E, Budagyan L, Totrov M, Sundstrom M, Marsden BD

Trends Biochem. Sci.. 31(2):76-8. doi: 10.1016/j.tibs.2005.12.006

Publication date: January 6, 2006

PMID: 16406633

2005

Structure and substrate specificity of the Pim-1 kinase.

Bullock AN, Debreczeni J, Amos AL, Knapp S, Turk BE

J. Biol. Chem.. 280(50):41675-82. doi: 10.1074/jbc.M510711200

Publication date: December 16, 2005

PMID: 16227208

Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease.

McDonough MA, Kavanagh KL, Butler D, Searls T, Oppermann U, Schofield CJ

J. Biol. Chem.. 280(49):41101-10. doi: 10.1074/jbc.M507528200

Publication date: December 9, 2005

PMID: 16186124

Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase.

Bullock AN, Debreczeni JE, Fedorov OY, Nelson A, Marsden BD, Knapp S

J. Med. Chem.. 48(24):7604-14. doi: 10.1021/jm0504858

Publication date: December 1, 2005

PMID: 16302800

Regulation of the wild-type and Y1235D mutant Met kinase activation.

Cristiani C, Rusconi L, Perego R, Schiering N, Kalisz HM, Knapp S, Isacchi A

Biochemistry. 44(43):14110-9. doi: 10.1021/bi051242k

Publication date: November 1, 2005

PMID: 16245927

The crystal structure of guinea pig 11beta-hydroxysteroid dehydrogenase type 1 provides a model for enzyme-lipid bilayer interactions.

Ogg D, Elleby B, Norström C, Stefansson K, Abrahmsén L, Oppermann U, Svensson S

J. Biol. Chem.. 280(5):3789-94. doi: 10.1074/jbc.M412463200

Publication date: February 4, 2005

PMID: 15542590

Displaying 1801 - 1823 of 1823
Download XLS