Publications

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Displaying 301 - 350 of 2157

2019

October 2019

Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation
Yu X, Plotnikova O, Bonin PD, Subashi TA, McLellan TJ, Dumlao D, Che Y, Dong YY, Carpenter EP, West GM, Qiu X, Culp JS, Han S
eLife 8:- . doi: 10.7554/eLife.48120
Publication date: October 2, 2019
PMID: 31580259

September 2019

Modular Synthesis of Di- and Trisubstituted Imidazoles from Ketones and Aldehydes: A Route to Kinase Inhibitors.
de Toledo I, Grigolo TA, Bennett JM, Elkins JM, Pilli RA
J Org Chem . doi: 10.1021/acs.joc.9b01844
Publication date: September 30, 2019
PMID: 31460764
SETD7 at the heart of chromatin factor interplay.
Barsyte-Lovejoy D
Stem Cell Investig 6:20 . doi: 10.21037/sci.2019.06.01
Publication date: September 29, 2019
PMID: 31559307
Fostering open collaboration in drug development for paediatric brain tumours.
Wong JF, Brown EJ, Williams E, Bullock AN
Biochem. Soc. Trans. . doi: 10.1042/BST20190315
Publication date: September 24, 2019
PMID: 31551357
A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.
Fagan V, Johansson C, Gileadi C, Monteiro O, Dunford JE, Nibhani R, Philpott M, Malzahn J, Wells G, Farham R, Cribbs A, Halidi N, Li F, Chau I, Greschik H, Velupillai S, Allali-Hassani A, Bennett JM, Christott T, Giroud C, Lewis AM, Huber KVM, Athanasou N, Bountra C, Jung M, Schüle R, Vedadi M, Arrowsmith CH, Xiong Y, Jin J, Fedorov O, Farnie G, Brennan PE, Oppermann UCT
J. Med. Chem. . doi: 10.1021/acs.jmedchem.9b00562
Publication date: September 24, 2019
PMID: 31550156
Fostering open collaboration in drug development for paediatric brain tumours
BULLOCK A, WILLIAMS E, WONG JF, Brown EJ
Biochemical Society Transactions 47:1471-1479 . doi: 10.1042/bst20190315
Publication date: September 23, 2019
PMID: 31551357
A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function
Fagan V, Johansson C, Gileadi C, Monteiro O, Dunford JE, Nibhani R, Philpott M, Malzahn J, Wells G, Farham R, Cribbs A, Halidi N, Li F, Chau I, Greschik H, Velupillai S, Allali-Hassani A, Bennett JM, Christott T, Giroud C, Lewis AM, Huber KVM, Athanasou N, Bountra C, Jung M, Schüle R, Vedadi M, Arrowsmith CH, Xiong Y, Jin J, Fedorov O, Farnie G, Brennan PE, Oppermann UCT
Journal of Medicinal Chemistry 62:9008-9025 . doi: 10.1021/acs.jmedchem.9b00562
Publication date: September 23, 2019
PMID: 31550156
Regulation of DGKε Activity and Substrate Acyl Chain Specificity by Negatively Charged Phospholipids.
Bozelli JC, Yune J, Hou YH, Chatha P, Fernandes A, Cao Z, Tong Y, Epand RM
Biophys. J. . doi: 10.1016/j.bpj.2019.09.008
Publication date: September 16, 2019
PMID: 31587830
The C-Terminal Domains SnRK2 Box and ABA Box Have a Role in Sugarcane SnRK2s Auto-Activation and Activity
Righetto GL, Sriranganadane D, Halabelian L, Chiodi CG, Elkins JM, Massirer KB, Gileadi O, Menossi M, Couñago RM
Frontiers in Plant Science 10:1105- . doi: 10.3389/fpls.2019.01105
Publication date: September 16, 2019
PMID: 31620147
Strategies to improve scFvs as crystallization chaperones suggested by analysis of a complex with the human PHD-bromodomain SP140
Fairhead M, Preger C, Wigren E, Strain-Damerell C, Ossipova E, Ye M, Makola M, Burgess-Brown NA, Persson H, von Delft F, Gräslund S
. doi: 10.1101/767376
Publication date: September 12, 2019
PMID:
Development of Pyridine-based Inhibitors for the Human Vaccinia-related Kinases 1 and 2.
Serafim RAM, de Souza Gama FH, Dutra LA, Dos Reis CV, Vasconcelos SNS, da Silva Santiago A, Takarada JE, Di Pillo F, Azevedo H, Mascarello A, Elkins JM, Massirer KB, Gileadi O, Guimarães CRW, Couñago RM
ACS Med Chem Lett 10(9):1266-1271 . doi: 10.1021/acsmedchemlett.9b00082
Publication date: September 12, 2019
PMID: 31531195
Development of Pyridine-based Inhibitors for the Human Vaccinia-related Kinases 1 and 2
Serafim RAM, De Souza Gama FH, Dutra LA, Dos Reis CV, Vasconcelos SNS, Da Silva Santiago A, Takarada JE, Di Pillo F, Azevedo H, Mascarello A, Elkins JM, Massirer KB, Gileadi O, Guimarães CRW, Couñago RM
ACS Medicinal Chemistry Letters 10:1266-1271 . doi: 10.1021/acsmedchemlett.9b00082
Publication date: September 12, 2019
PMID: 31531195
A Chemical Probe Targeting AAK1 and BMP2K
Wells C, Counago R, Limas J, Almeida T, Cook J, Drewry D, Elkins J, Gileadi O, Kapadia N, Lorente-Macías Á, Pickett J, Riemen A, R. Ruela-de-Sousa R, Willson T, Zhang C, Zuercher W, Zutshi R, Axtman A
. doi: 10.26434/chemrxiv.9756785.v1
Publication date: September 3, 2019
PMID:
Structural basis for recruitment of DAPK1 to the KLHL20 E3 ligase
BULLOCK A, CHEN Z, PICAUD S, FILIPPAKOPOULOS P, D'ANGIOLELLA V
Structure 27:1395-1404.e4 . doi: 10.1016/j.str.2019.06.005
Publication date: September 3, 2019
PMID: 31279627
The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Bushell SR, Pike ACW, Falzone ME, Rorsman NJG, Ta CM, Corey RA, Newport TD, Christianson JC, Scofano LF, Shintre CA, Tessitore A, Chu A, Wang Q, Shrestha L, Mukhopadhyay SMM, Love JD, Burgess-Brown NA, Sitsapesan R, Stansfeld PJ, Huiskonen JT, Tammaro P, Accardi A, Carpenter EP
Nat Commun 10(1):3956 . doi: 10.1038/s41467-019-11753-1
Publication date: September 2, 2019
PMID: 31477691
LYAR potentiates rRNA synthesis by recruiting BRD2/4 and the MYST-type acetyltransferase KAT7 to rDNA.
Izumikawa K, Ishikawa H, Yoshikawa H, Fujiyama S, Watanabe A, Aburatani H, Tachikawa H, Hayano T, Miura Y, Isobe T, Simpson RJ, Li L, Min J, Takahashi N
Nucleic Acids Res. . doi: 10.1093/nar/gkz747
Publication date: September 2, 2019
PMID: 31504794
The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K
Bushell SR, Pike ACW, Falzone ME, Rorsman NJG, Ta CM, Corey RA, Newport TD, Christianson JC, Scofano LF, Shintre CA, Tessitore A, Chu A, Wang Q, Shrestha L, Mukhopadhyay SMM, Love JD, Burgess-Brown NA, Sitsapesan R, Stansfeld PJ, Huiskonen JT, Tammaro P, Accardi A, Carpenter EP
Nature Communications 10:3956- . doi: 10.1038/s41467-019-11753-1
Publication date: September 1, 2019
PMID: 31477691
C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4)inhibitors, compound profiling in cell-based target engagement assays
Le Bihan YV, Lanigan RM, Atrash B, McLaughlin MG, Velupillai S, Malcolm AG, England KS, Ruda GF, Mok NY, Tumber A, Tomlin K, Saville H, Shehu E, McAndrew C, Carmichael LA, Bennett JM, Jeganathan F, Eve P, Donovan A, Hayes A, Wood F, Raynaud FI, Fedorov O, Brennan PE, Burke R, van Montfort RLM, Rossanese OW, Blagg J, Bavetsias V
European Journal of Medicinal Chemistry 177:316-337 . doi: 10.1016/j.ejmech.2019.05.041
Publication date: September 1, 2019
PMID: 31158747

August 2019

Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target
Alam MM, Sanchez-Azqueta A, Janha O, Flannery EL, Mahindra A, Mapesa K, Char AB, Sriranganadane D, Brancucci NMB, Antonova-Koch Y, Crouch K, Simwela NV, Millar SB, Akinwale J, Mitcheson D, Solyakov L, Dudek K, Jones C, Zapatero C, Doerig C, Nwakanma DC, Vázquez MJ, Colmenarejo G, Lafuente-Monasterio MJ, Leon ML, Godoi PHC, Elkins JM, Waters AP, Jamieson AG, Álvaro EF, Ranford-Cartwright LC, Marti M, Winzeler EA, Gamo FJ, Tobin AB
Science 365:884-+ . doi: 10.1126/science.aau1682
Publication date: August 30, 2019
PMID: 31467193
Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target.
Alam MM, Sanchez-Azqueta A, Janha O, Flannery EL, Mahindra A, Mapesa K, Char AB, Sriranganadane D, Brancucci NMB, Antonova-Koch Y, Crouch K, Simwela NV, Millar SB, Akinwale J, Mitcheson D, Solyakov L, Dudek K, Jones C, Zapatero C, Doerig C, Nwakanma DC, Vázquez MJ, Colmenarejo G, Lafuente-Monasterio MJ, Leon ML, Godoi PHC, Elkins JM, Waters AP, Jamieson AG, Álvaro EF, Ranford-Cartwright LC, Marti M, Winzeler EA, Gamo FJ, Tobin AB
Science 365(6456): . doi: 10.1126/science.aau1682
Publication date: August 30, 2019
PMID: 31467193
The natural history of infantile mitochondrial DNA depletion syndrome due to RRM2B deficiency.
Keshavan N, Abdenur J, Anderson G, Assouline Z, Barcia G, Bouhikbar L, Chakrapani A, Cleary M, Cohen MC, Feillet F, Fratter C, Hauser N, Jacques T, Lam A, McCullagh H, Phadke R, Rötig A, Sharrard M, Simon M, Smith C, Sommerville EW, Taylor RW, Yue WW, Rahman S
Genet. Med. . doi: 10.1038/s41436-019-0613-z
Publication date: August 29, 2019
PMID: 31462754
The natural history of infantile mitochondrial DNA depletion syndrome due to RRM2B deficiency
Keshavan N, Abdenur J, Anderson G, Assouline Z, Barcia G, Bouhikbar L, Chakrapani A, Cleary M, Cohen MC, Feillet F, Fratter C, Hauser N, Jacques T, Lam A, McCullagh H, Phadke R, Rötig A, Sharrard M, Simon M, Smith C, Sommerville EW, Taylor RW, Yue WW, Rahman S
Genetics in Medicine . doi: 10.1038/s41436-019-0613-z
Publication date: August 29, 2019
PMID: 31462754
Modular Synthesis of Di- and Tri-substituted Imidazoles from Ketones and Aldehydes: A Route to Kinase Inhibitors.
Toledo I, Grigolo TA, Bennett JM, Elkins JM, Pilli RA
J. Org. Chem. . doi: 10.1021/acs.joc.9b01844
Publication date: August 28, 2019
PMID: 31460764
Open laboratory notebooks: good for science, good for society, good for scientists.
Schapira M, Harding RJ
F1000Res 8:87 . doi: 10.12688/f1000research.17710.1
Publication date: August 27, 2019
PMID: 31448096
Target highlights in CASP13: experimental target structures through the eyes of their authors.
Lepore R, Kryshtafovych A, Alahuhta M, Arora Veraszto H, Bomble YJ, Bufton JC, Bullock AN, Caba C, Cao H, Davies OR, Desfosses A, Dunne M, Fidelis K, Goulding CW, Gurusaran M, Gutsche I, Harding CJ, Hartmann MD, Hayes CS, Joachimiak A, Leiman PG, Loppnau P, Lovering AL, Lunin VV, Michalska K, Mir-Sanchis I, Mitra A, Moult J, Phillips GN, Pinkas DM, Rice PA, Tong Y, Topf M, Walton JD, Schwede T
Proteins . doi: 10.1002/prot.25805
Publication date: August 23, 2019
PMID: 31442339
Discovery of first in vivo active inhibitors of soluble epoxide hydrolase (sEH) phosphatase domain.
Kramer JS, Woltersdorf S, Duflot T, Hiesinger K, Lillich FF, Knöll F, Wittmann SK, Klingler FM, Brunst S, Chaikuad A, Morisseau C, Hammock BD, Buccellati C, Sala A, Rovati GE, Leuillier M, Fraineau S, Rondeaux J, Hernandez Olmos V, Heering J, Merk D, Pogoryelov D, Steinhilber D, Knapp S, Bellien J, Proschak E
J. Med. Chem. . doi: 10.1021/acs.jmedchem.9b00445
Publication date: August 22, 2019
PMID: 31436984
Evaluation of linker length effects on a BET bromodomain probe
Traquete R, Henderson E, Picaud S, Cal PMSD, Sieglitz F, Rodrigues T, Oliveira R, Filippakopoulos P, Bernardes GJL
Chemical Communications 55:10128-10131 . doi: 10.1039/c9cc05054j
Publication date: August 20, 2019
PMID: 31386708
E2F1 proteolysis via SCF-cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition.
Burdova K, Yang H, Faedda R, Hume S, Chauhan J, Ebner D, Kessler BM, Vendrell I, Drewry DH, Wells CI, Hatch SB, Dianov GL, Buffa FM, D'Angiolella V
EMBO J. e101443 . doi: 10.15252/embj.2018101443
Publication date: August 19, 2019
PMID: 31424118
Targeting an EGFR water network using novel 4-anilinoquin(az)olines inhibitors for chordoma.
Asquith CRM, Maffuid KA, Laitinen T, Torrice C, Tizzard GJ, Crona DJ, Zuercher WJ
ChemMedChem . doi: 10.1002/cmdc.201900428
Publication date: August 19, 2019
PMID: 31424613
Selective, small molecule co-factor binding site inhibition of a Su(var)3-9, Enhancer of Zeste, Trithorax (SET) domain containing lysine methyltransferase.
Taylor AP, Szewczyk MM, Kennedy S, Trush VV, Wu H, Zeng H, Dong A, de Freitas RF, Tatlock JH, Kumpf RA, Wythes M, Casimiro-Garcia A, Denny RA, Parikh MD, Li F, Barsyte-Lovejoy D, Schapira M, Vedadi M, Brown P, Arrowsmith CH, Owen DR
J. Med. Chem. . doi: 10.1021/acs.jmedchem.9b00112
Publication date: August 15, 2019
PMID: 31415173
Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation.
Fong JY, Pignata L, Goy PA, Kawabata KC, Lee SC, Koh CM, Musiani D, Massignani E, Kotini AG, Penson A, Wun CM, Shen Y, Schwarz M, Low DH, Rialdi A, Ki M, Wollmann H, Mzoughi S, Gay F, Thompson C, Hart T, Barbash O, Luciani GM, Szewczyk MM, Wouters BJ, Delwel R, Papapetrou EP, Barsyte-Lovejoy D, Arrowsmith CH, Minden MD, Jin J, Melnick A, Bonaldi T, Abdel-Wahab O, Guccione E
Cancer Cell 36(2):194-209.e9 . doi: 10.1016/j.ccell.2019.07.003
Publication date: August 12, 2019
PMID: 31408619
The MLL1 trimeric catalytic complex is a dynamic conformational ensemble stabilized by multiple weak interactions.
Kaustov L, Lemak A, Wu H, Faini M, Fan L, Fang X, Zeng H, Duan S, Allali-Hassani A, Li F, Wei Y, Vedadi M, Aebersold R, Wang Y, Houliston S, Arrowsmith CH
Nucleic Acids Res. . doi: 10.1093/nar/gkz697
Publication date: August 10, 2019
PMID: 31400120
Evaluation of linker length effects on a BET bromodomain probe.
Traquete R, Henderson E, Picaud S, Cal PMSD, Sieglitz F, Rodrigues T, Oliveira R, Filippakopoulos P, Bernardes GJL
Chem. Commun. (Camb.) . doi: 10.1039/c9cc05054j
Publication date: August 6, 2019
PMID: 31386708
A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin
Lim M, Newman JA, Williams HL, Masino L, Aitkenhead H, Gravard AE, Gileadi O, Svejstrup JQ
Structure 27:1316-1325.e6 . doi: 10.1016/j.str.2019.05.003
Publication date: August 6, 2019
PMID: 31204252
RIOK2: straddling the kinase/ATPase line.
Asquith CRM, East MP, Zuercher WJ
Nat Rev Drug Discov 18(8):574 . doi: 10.1038/d41573-019-00107-7
Publication date: August 2, 2019
PMID: 31367048
2-Amino-2,3-dihydro-1H-indene-5-carboxamide-Based Discoidin Domain Receptor 1 (DDR1) Inhibitors: Design, Synthesis, and in Vivo Antipancreatic Cancer Efficacy
Zhu D, Huang H, Pinkas DM, Luo J, Ganguly D, Fox AE, Arner E, Xiang Q, Tu Z-C, Bullock AN, Brekken RA, Ding K, Lu X
Journal of Medicinal Chemistry 62:7431-7444 . doi: 10.1021/acs.jmedchem.9b00365
Publication date: August 2, 2019
PMID: 31310125
Regulation of influenza A virus mRNA splicing by CLK1
Artarini A, Meyer M, Shin YJ, Huber K, Hilz N, Bracher F, Eros D, Orfi L, Keri G, Goedert S, Neuenschwander M, von Kries J, Domovich-Eisenberg Y, Dekel N, Szabadkai I, Lebendiker M, Horváth Z, Danieli T, Livnah O, Moncorgé O, Frise R, Barclay W, Meyer TF, Karlas A
Antiviral Research 168:187-196 . doi: 10.1016/j.antiviral.2019.06.003
Publication date: August 1, 2019
PMID: 31176694

July 2019

Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain.
Lei M, Tempel W, Chen S, Liu K, Min J
Biochim Biophys Acta Gene Regul Mech 194409 . doi: 10.1016/j.bbagrm.2019.194409
Publication date: July 26, 2019
PMID: 31356990
Structural mechanism of synergistic activation of Aurora kinase B/C by phosphorylated INCENP
Abdul Azeez KR, Chatterjee S, Yu C, Golub TR, Sobott F, Elkins JM
Nature Communications 10:3166- . doi: 10.1038/s41467-019-11085-0
Publication date: July 18, 2019
PMID: 31320618
Structural mechanism of synergistic activation of Aurora kinase B/C by phosphorylated INCENP.
Abdul Azeez KR, Chatterjee S, Yu C, Golub TR, Sobott F, Elkins JM
Nat Commun 10(1):3166 . doi: 10.1038/s41467-019-11085-0
Publication date: July 18, 2019
PMID: 31320618
2-Amino-2, 3-Dihydro-1H-Indene-5-Carboxamide-Based Discoidin Domain Receptors 1 (DDR1) Inhibitors: Design, Synthesis, and In Vivo Anti-pancreatic Cancer Efficacy.
Zhu D, Huang H, Pinkas D, Luo J, Ganguly D, Fox AE, Arner E, Xiang Q, Tu ZC, Bullock AN, Brekken RA, Ding K, Lu X
J. Med. Chem. . doi: 10.1021/acs.jmedchem.9b00365
Publication date: July 16, 2019
PMID: 31310125
Identification and characterization of the first fragment hits for SETDB1 Tudor domain.
Mader P, Mendoza-Sanchez R, Iqbal A, Dong A, Dobrovetsky E, Corless VB, Liew SK, Houliston SR, De Freitas RF, Smil D, Sena CCD, Kennedy S, Diaz DB, Wu H, Dombrovski L, Allali-Hassani A, Min J, Schapira M, Vedadi M, Brown PJ, Santhakumar V, Yudin AK, Arrowsmith CH
Bioorg. Med. Chem. . doi: 10.1016/j.bmc.2019.07.020
Publication date: July 12, 2019
PMID: 31327677
Anti-tubercular activity of novel 4-anilinoquinolines and 4-anilinoquinazolines.
Asquith CRM, Fleck N, Torrice CD, Crona DJ, Grundner C, Zuercher WJ
Bioorg. Med. Chem. Lett. . doi: 10.1016/j.bmcl.2019.07.012
Publication date: July 10, 2019
PMID: 31378571
Gram-scale synthesis of FICZ, a photoreactive endogenous ligand of the aryl hydrocarbon receptor.
Zhang C, Creech KL, Zuercher WJ, Willson TM
Sci Rep 9(1):9982 . doi: 10.1038/s41598-019-46374-7
Publication date: July 10, 2019
PMID: 31292477
Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.
Labuhn M, Perkins K, Matzk S, Varghese L, Garnett C, Papaemmanuil E, Metzner M, Kennedy A, Amstislavskiy V, Risch T, Bhayadia R, Samulowski D, Hernandez DC, Stoilova B, Iotchkova V, Oppermann U, Scheer C, Yoshida K, Schwarzer A, Taub J, Crispino JD, Weiss MJ, Hayashi A, Taga T, Ito E, Ogawa S, Reinhardt D, Yaspo ML, Campbell PJ, Roberts I, Constantinescu S, Vyas P, Heckl D, Klusmann JH
Cancer Cell . doi: 10.1016/j.ccell.2019.06.007
Publication date: July 9, 2019
PMID: 31303423
A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.
Sin-Chan P, Mumal I, Suwal T, Ho B, Fan X, Singh I, Du Y, Lu M, Patel N, Torchia J, Popovski D, Fouladi M, Guilhamon P, Hansford JR, Leary S, Hoffman LM, Mulcahy Levy JM, Lassaletta A, Solano-Paez P, Rivas E, Reddy A, Gillespie GY, Gupta N, Van Meter TE, Nakamura H, Wong TT, Ra YS, Kim SK, Massimi L, Grundy RG, Fangusaro J, Johnston D, Chan J, Lafay-Cousin L, Hwang EI, Wang Y, Catchpoole D, Michaud J, Ellezam B, Ramanujachar R, Lindsay H, Taylor MD, Hawkins CE, Bouffet E, Jabado N, Singh SK, Kleinman CL, Barsyte-Lovejoy D, Li XN, Dirks PB, Lin CY, Mack SC, Rich JN, Huang A
Cancer Cell 36(1):51-67.e7 . doi: 10.1016/j.ccell.2019.06.002
Publication date: July 8, 2019
PMID: 31287992
Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3.
Böttcher J, Dilworth D, Reiser U, Neumüller RA, Schleicher M, Petronczki M, Zeeb M, Mischerikow N, Allali-Hassani A, Szewczyk MM, Li F, Kennedy S, Vedadi M, Barsyte-Lovejoy D, Brown PJ, Huber KVM, Rogers CM, Wells CI, Fedorov O, Rumpel K, Zoephel A, Mayer M, Wunberg T, Böse D, Zahn S, Arnhof H, Berger H, Reiser C, Hörmann A, Krammer T, Corcokovic M, Sharps B, Winkler S, Häring D, Cockcroft XL, Fuchs JE, Müllauer B, Weiss-Puxbaum A, Gerstberger T, Boehmelt G, Vakoc CR, Arrowsmith CH, Pearson M, McConnell DB
Nat. Chem. Biol. . doi: 10.1038/s41589-019-0310-x
Publication date: July 8, 2019
PMID: 31285596
Peptide Hydrogels of Fully-Defined Composition & Mechanics for Probing Cell-Cell & Cell-Matrix Interactions In Vitro
Ashworth J, Thompsona J, Jamesa J, Slatera C, Pijuan-Galitoa S, Lis-Slimaka K, Holleyc R, Mead K, Thompsone A, Arkille K, Tassierif M, Wrightg A, FARNIE G, merry C
Matrix Biology . doi: 10.1016/j.matbio.2019.06.009
Publication date: July 8, 2019
PMID: 31295578
Lesson from a Fab-enabled co-crystallization study of TDRD2 and PIWIL1.
Chen S, Zhang W, Min J, Liu K
Methods . doi: 10.1016/j.ymeth.2019.07.002
Publication date: July 6, 2019
PMID: 31288074
High-Throughput Site-Directed Mutagenesis.
Strain-Damerell C, Burgess-Brown NA
Methods Mol. Biol. 2025:281-296 . doi: 10.1007/978-1-4939-9624-7_13
Publication date: July 4, 2019
PMID: 31267458

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