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Home » Reagents & Resources » Resources » Structure Gallery

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2253 structures found


	PDB: 7KYX Target: CORO6 Deposited: 09/12/2020 Human Coronin-6, WDR domain Target Class: WDR Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 7KXT Target: EED Deposited: 04/12/2020 Human Polycomb protein EED, WDR domain, in complex with Astemizole Target Class: WDR Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 7KQQ Target: WDR55 Deposited: 16/11/2020 WD repeat-containing protein 55, WDR domain Target Class: WDR Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 7KLJ Target: KIF21A Deposited: 04/11/2020 Human Kinesin-like protein KIF21A, WDR domain Target Class: WDR Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 7JYA Target: FEM1C Deposited: 29/08/2020 Human E3 ligase protein fem-1 homolog C, ankyrin repeat, in complex with peptide Target Class: Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 6XKC Target: FEM1C Deposited: 25/06/2020 Human protein fem-1 homolog C, N-terminal ankyrin repeat Target Class: Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 6XKB Target: SCAF4 Deposited: 25/06/2020 Human SR-related and CTD-associated factor 4, CID domain, in complex with peptide S2,S5p-CTD Target Class: Miscellaneous Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 6XCG Target: WHSC1 Deposited: 08/06/2020 Human histone-lysine N-methyltransferase NSD2, first PWWP domain, in complex with chemical probe UNC6934 Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 6WZZ Target: GID4 Deposited: 14/05/2020 Human Glucose-induced degradation protein 4, substrate binding domain, in complex VGLWKS peptide Target Class: Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: Follow-up official


	PDB: 6YWL Target: CVNSP3B Deposited: 30/04/2020 Crystal structure of SARS-CoV-2 (Covid-19) NSP3 macrodomain in complex with ADP-ribose Target Class: Disease Areas: SARS-COV-2 Site: Frankfurt Status:


	PDB: 6YWK Target: CVNSP3B Deposited: 30/04/2020 Crystal structure of SARS-CoV-2 (Covid-19) NSP3 macrodomain in complex with HEPES Target Class: Disease Areas: SARS-COV-2 Site: Frankfurt Status:


	PDB: 6YWM Target: CVNSP3B Deposited: 30/04/2020 Crystal structure of SARS-CoV-2 (Covid-19) NSP3 macrodomain in complex with MES Target Class: Disease Areas: SARS-COV-2 Site: Frankfurt Status:

FBXW11/SKP1 - Beta Catenin


	PDB: 6WNX Target: FBXW11/SKP1 - Beta Catenin Deposited: 23/04/2020 Human F-box/WD repeat-containing protein 11, F-box and WDR domains, in complex with SKP1 and a pSer33/pSer37 Beta-Catenin peptide Target Class: Ubiquitylation - E3 Ligases, WDR Disease Areas: Signalling and cancer Site: Toronto Status: Counted


	PDB: 6WHH Target: WDR41 Deposited: 08/04/2020 Human WD repeat-containing protein 41, WDR domain Target Class: WDR Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6WAT Target: PHF1 Deposited: 31/03/2020 Human PHD finger protein 1, Tudor domain, in complex with H3K27me3 peptide Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6WAV Target: PHF1 Deposited: 31/03/2020 Human PHD finger protein 1, Tudor domain, in complex with H3K36me3 peptide Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6WAU Target: PHF19 Deposited: 31/03/2020 Human PHD finger protein 19, Tudor domain, in complex with H3K27me3 peptide Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6WAJ Target: NLE1 Deposited: 25/03/2020 Human Notchless protein homolog 1, N-terminal ubiquitin-like domain Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6VYC Target: WDR91 Deposited: 26/02/2020 Human WD repeat-containing protein 91, WDR domain Target Class: WDR Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 6VTI Target: PPP1R10 Deposited: 12/02/2020 Human Serine/threonine-protein phosphatase 1 regulatory subunit 10, N-terminal domain Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6VAH Target: TEAD2 Deposited: 23/12/2019 Human TEA domain transcription factor 2, YAP binding domain, in complex with flufenamic acid derivative Target Class: Miscellaneous Disease Areas: Signalling and cancer Site: Toronto Status: Follow-up official


	PDB: 6VCS Target: UHRF1 Deposited: 23/12/2019 Human ubiquitin like with PHD and ring finger domains 1, SRA domain, in complex with DNA Target Class: Miscellaneous Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6VA5 Target: 53BP1 Deposited: 20/12/2019 Human tumor protein p53 binding protein 1, tudor domain, in complex with inhibitor MFP-4184 Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6V9T Target: TDRD3 Deposited: 16/12/2019 Human tudor domain containing 3, tudor domain, in complex with small molecule Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 6V3N Target: CDYL2 Deposited: 10/12/2019 Human chromodomain Y like 2, chromodomain, in complex with H3K27me3 peptide Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6TN8 Target: ACVR1 Deposited: 06/12/2019 Human activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6V41 Target: CDY1 Deposited: 27/11/2019 Human chromodomain Y-linked 1, chromodomain, in complex with H3K9me3 peptide Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6V2S Target: MPP8 Deposited: 25/11/2019 Human M-phase phosphoprotein 8, chromodomain, in complex with peptido-mimetic UNC3866 Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6V2D Target: CDYL2 Deposited: 22/11/2019 Human chromodomain Y like 2, chromodomain, in complex with peptido-mimetic UNC3866 Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 6T8N Target: ACVR1 Deposited: 24/10/2019 Human activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6T6D Target: ACVR1 Deposited: 18/10/2019 Human activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6UPT Target: 53BP1 Deposited: 18/10/2019 Human tumor protein p53 binding protein 1, tudor domain, in complex with inhibitor MFP-2706 Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6SZM Target: ACVR1 Deposited: 02/10/2019 Human activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6UHD Target: HAT1 Deposited: 27/09/2019 Human histone acetyltransferase 1, full length, in complex with isobutyryl-CoA and H4K12A mutant Target Class: Chromatin Regulation, Transferases Disease Areas: Epigenetics Site: Toronto Status: Follow-up official


	PDB: 6SY1 Target: DHTKD1 Deposited: 26/09/2019 Human dehydrogenase E1 and transketolase domain containing 1 Target Class: Oxidoreductases Disease Areas: Metabolism Site: Oxford Status: Counted


	PDB: 6UE6 Target: WHSC1 Deposited: 20/09/2019 Human nuclear receptor binding SET domain protein 2, first PWWP domain, in complex with small molecule MR837 Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6SRH Target: ACVR1 Deposited: 05/09/2019 Human activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6SFO Target: MAPK14A Deposited: 01/08/2019 MAPK14 with bound inhibitor SR-318 Target Class: Protein Kinase/CMGC Disease Areas: Site: Frankfurt Status: Follow-up not counted


	PDB: 6SE4 Target: BRD4 Deposited: 29/07/2019 Human bromodomain containing 4 Target Class: Bromodomain Disease Areas: Cancer and epigenetics Site: Oxford Status: MedChem


	PDB: 6S5F Target: RAB39B Deposited: 01/07/2019 Human RAB39B, member RAS oncogene family Target Class: Vesicle Transport Disease Areas: Cancer Site: Oxford Status: Counted


	PDB: 6S5H Target: RAB38 Deposited: 01/07/2019 Human RAB38, member RAS oncogene family Target Class: Vesicle Transport Disease Areas: Cancer Site: Oxford Status: Counted


	PDB: 6PFL Target: HUWE1 Deposited: 21/06/2019 Human HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase, WWE domain, in complex with ADP-ribose Target Class: Ubiquitin Related Biology Disease Areas: Cancer Site: Toronto Status: Follow-up official


	PDB: 6PED Target: N6AMT1-TRMT112 Deposited: 20/06/2019 Human methyltransferase dimer N6AMT1-TRMT112, methyltransferase domain, in complex with S-adenosyl-homocysteine Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6PDM Target: PRMT9 Deposited: 19/06/2019 Human protein arginine methyltransferase 9, full-length Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6PBG Target: COPA Deposited: 13/06/2019 Human coatomer protein complex subunit alpha, WDR domain Target Class: WDR Disease Areas: Neurobiology Site: Toronto Status: Counted


	PDB: 6P7I Target: HRMT1L6 Deposited: 05/06/2019 Human protein arginine methyltransferase 6, full-length, in complex with covalent inhibitor YS17-117 Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6P0R Target: SUV39H2 Deposited: 17/05/2019 Human suppressor of variegation 3-9 homolog 2, methyltransferase domain, in complex with inhibitor OTS186935 Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6P0Q Target: WDR12 Deposited: 17/05/2019 Human WD repeat domain 12, ubiquitin-like domain Target Class: Ubiquitin Related Biology Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6OQM Target: MSH6 Deposited: 26/04/2019 Human mutS homolog 6, PWWP domain Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6NP7 Target: BDF2 Deposited: 17/04/2019 Trypanosoma cruzi TcCLB.506553.20, bromodomain Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Counted


	PDB: 6FNU Target: MET12SCA Deposited: 17/04/2019 Structure of S. cerevisiae Methylenetetrahydrofolate reductase 1, catalytic domain Target Class: Disease Areas: Site: Oxford Status: Official


	PDB: 6RCT Target: CLK3A Deposited: 11/04/2019 Crystal structure of CLK3 in complex with T3-CLK Target Class: Protein Kinase/CMGC Disease Areas: Site: Frankfurt Status: Not counted


	PDB: 6RAA Target: CLK1A Deposited: 05/04/2019 CLK1 Kinase domain with bound imidazopyridin inhibitor T3-CLK Target Class: Protein Kinase/CMGC Disease Areas: Site: Frankfurt Status: MedChem


	PDB: 6OGN Target: PRMT7 Deposited: 03/04/2019 Mouse protein arginine methyltransferase 7, full-length, in complex with chemical probe SGC8158 Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6OGK Target: MECP2 Deposited: 02/04/2019 Human methyl-CpG binding protein 2, MBD domain, in complex with A(5CM)AC DNA Target Class: Chromatin Regulation Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6OGJ Target: MECP2 Deposited: 02/04/2019 Human methyl-CpG binding protein 2, MBD domain, in complex with ACAC DNA Target Class: Chromatin Regulation Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6OE7 Target: HMCES Deposited: 27/03/2019 Human 5-hydroxymethylcytosine binding ES cell specific, SRAP domain, cross-linked to DNA abasic site Target Class: RNA/DNA Processing/DNA-Repair Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6OEA Target: HMCES Deposited: 27/03/2019 Human 5-hydroxymethylcytosine binding ES cell specific, SRAP domain, in complex with longer 3' overhang DNA Target Class: RNA/DNA Processing/DNA-Repair Disease Areas: Cancer Site: Toronto Status: Not counted


	PDB: 6OEB Target: HMCES Deposited: 27/03/2019 Human 5-hydroxymethylcytosine binding ES cell specific, SRAP domain, in complex with 3' overhang DNA Target Class: RNA/DNA Processing/DNA-Repair Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6QU2 Target: DYRK1AA Deposited: 26/02/2019 Crystal structure of DYRK1A complexed with FC162 inhibitor Target Class: Protein Kinase/CMGC Disease Areas: Signalling and cancer Site: Frankfurt Status: Not counted


	PDB: 5QHN Target: FAM83BA Deposited: 07/02/2019 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000622a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 6GI6 Target: ACVR1A Deposited: 07/02/2019 Crystal structure of the ACVR1 (ALK2) kinase in complex with a Quinazolinone based ALK2 inhibitor with a 5-methyl core. Target Class: Protein Kinase/TKL Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6NM4 Target: PRDM9 Deposited: 10/01/2019 Human PR/SET domain 9, methyltransferase domain, in complex with chemical probe MRK-740 Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: MedChem


	PDB: 6QD5 Target: SLC14A1A Deposited: 31/12/2018 X-ray Structure of the Human Urea Channel SLC14A1/UT1 Target Class: Membrane proteins Disease Areas: Site: Oxford Status: Official


	PDB: 6NFX Target: MBTD1 Deposited: 29/12/2018 Human MBT domain-containing protein 1, MBT repeat, in complex with EPC1 peptide Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6QB7 Target: KCTD16A Deposited: 20/12/2018 Structure of the H1 domain of human KCTD16 Target Class: Ubiquitin Related Biology Disease Areas: Site: Oxford Status: Official


	PDB: 6NFT Target: USP05 Deposited: 20/12/2018 Human ubiquitin specific peptidase 5, second ZnF domain, in complex with inhibitor DAT194 Target Class: Deubiquitinating Enzymes - USP, Ubiquitin Related Biology Disease Areas: Signalling and cancer Site: Toronto Status: MedChem


	PDB: 6QAV Target: ULK2A Deposited: 19/12/2018 Crystal structure of ULK2 in complexed with MRT68921 Target Class: Protein Kinase Disease Areas: Autophagy and cancer Site: Frankfurt Status: Official


	PDB: 6QAU Target: ULK2A Deposited: 19/12/2018 Crystal structure of ULK2 in complexed with MRT67307 Target Class: Protein Kinase Disease Areas: Autophagy and cancer Site: Frankfurt Status: Follow-up official


	PDB: 6QAT Target: ULK2A Deposited: 19/12/2018 Crystal structure of ULK2 in complexed with hesperadin Target Class: Protein Kinase Disease Areas: Autophagy and cancer Site: Frankfurt Status: Follow-up official


	PDB: 6QAS Target: ULK1A Deposited: 19/12/2018 Crystal structure of ULK1 in complexed with PF-03814735 Target Class: Protein Kinase Disease Areas: Autophagy and cancer Site: Frankfurt Status: Follow-up official


	PDB: 6NEZ Target: PP-BRD3 Deposited: 18/12/2018 Trypanosoma brucei BDF5 (Tb427tmp.01.5000), bromodomain, in complex with inhibitor PF-CBP1 Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 6NEY Target: PP-BRD3 Deposited: 18/12/2018 Trypanosoma cruzi TcCLB.506755.120, bromodomain Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Counted


	PDB: 6Q8P Target: CLK1A Deposited: 16/12/2018 Structure of CLK1 with bound N-methyl-10-nitropyrido[3,4-g]quinazolin-2-amine Target Class: Protein Kinase/CMGC Disease Areas: Signalling and cancer Site: Frankfurt Status: Follow-up not counted


	PDB: 6Q8K Target: CLK1A Deposited: 15/12/2018 CLK1 with bound pyridoquinazoline inhibitor Target Class: Protein Kinase/CMGC Disease Areas: Signalling and cancer Site: Frankfurt Status: Follow-up not counted


	PDB: 6NIM Target: PP-BRD18 Deposited: 26/11/2018 Trypanosoma cruzi TcCLB.506553.20, bromodomain, in complex with bromosporine Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 6I8Y Target: SPIN1A Deposited: 22/11/2018 Crystal structure of Spindlin1 in complex with the Methyltransferase inhibitor A366 Target Class: Protein Kinase/STE Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6I8L Target: SPIN1A Deposited: 21/11/2018 Crystal structure of Spindlin1 in complex with the inhibitor TD001851a Target Class: SPINDLIN Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6I8B Target: SPIN1A Deposited: 20/11/2018 Crystal structure of Spindlin1 in complex with the inhibitor VinSpinIn Target Class: SPINDLIN Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6N31 Target: WDR12 Deposited: 14/11/2018 Human WD repeat domain 12, WDR domain Target Class: WDR Disease Areas: Signalling and cancer Site: Toronto Status: Counted


	PDB: 6I2Y Target: STK10A Deposited: 02/11/2018 Human STK10 bound to Foretinib Target Class: Protein Kinase/STE Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6HXF Target: STK10A Deposited: 17/10/2018 Human STK10 bound to a maleimide inhibitor Target Class: Protein Kinase/STE Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6HVD Target: SLKA Deposited: 11/10/2018 Human SLK bound to a maleimide inhibitor Target Class: Protein Kinase/STE Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6HT1 Target: MLLT1A Deposited: 02/10/2018 Crystal structure of MLLT1 (ENL) YEATS domain in complexed with SGC-iMLLT Target Class: YEATS Disease Areas: Cancer and epigenetics Site: Frankfurt Status: Follow-up official


	PDB: 6ht0 Target: MLLT1A Deposited: 02/10/2018 Crystal structure of MLLT1 (ENL) YEATS domain in complexed with compound 94 (a SGC iMLLT derivative) Target Class: YEATS Disease Areas: Cancer and epigenetics Site: Frankfurt Status: MedChem


	PDB: 6MLC Target: MLL3 Deposited: 29/09/2018 Human lysine methyltransferase 2C, 6th PHD domain, in complex with H4 peptide Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6MIW Target: HUWE1 Deposited: 25/09/2018 Human HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase, WWE domain Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6ICT Target: SETD3 Deposited: 25/09/2018 Human SET Domain-Containing Protein 3, methyltransferase domain, in complex with methylated β-actin peptide Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6hpw Target: MLLT1A Deposited: 22/09/2018 Crystal structure of ENL (MLLT1) in complex with compound 20 (YTOOA000430a) Target Class: YEATS Disease Areas: Cancer and epigenetics Site: Frankfurt Status: MedChem


	PDB: 6hpx Target: MLLT1A Deposited: 22/09/2018 Crystal structure of ENL (MLLT1) in complex with compound 19 (benzimidazole fragment EF00114a) Target Class: YEATS Disease Areas: Cancer and epigenetics Site: Frankfurt Status: MedChem


	PDB: 6hpy Target: MLLT1A Deposited: 22/09/2018 Crystal structure of ENL (MLLT1) in complex with compound 12 (fragment EF00292) Target Class: YEATS Disease Areas: Cancer and epigenetics Site: Frankfurt Status: MedChem


	PDB: 6hpz Target: MLLT1A Deposited: 22/09/2018 Crystal structure of ENL (MLLT1) in complex with acetyllysine Target Class: YEATS Disease Areas: Cancer and epigenetics Site: Frankfurt Status: MedChem


	PDB: 6hq0 Target: MLLT1A Deposited: 22/09/2018 Crystal structure of ENL (MLLT1), apo form Target Class: YEATS Disease Areas: Cancer and epigenetics Site: Frankfurt Status: Follow-up not counted


	PDB: 6HP9 Target: DDR1A Deposited: 19/09/2018 Structure of the kinase domain of human DDR1 in complex with a 2-Amino-2,3-Dihydro-1H-Indene-5-Carboxamide-based inhibitor Target Class: Kinase-TK Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6MF9 Target: PP-BRD12 Deposited: 10/09/2018 Cryptosporidium parvum bromodomain containing protein 12 (cgd4_650), bromodomain, in complex with inhibitor BI-2536 Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Counted


	PDB: 6ICV Target: SETD3 Deposited: 07/09/2018 Human SET Domain-Containing Protein 3, methyltransferase domain, in complex with unmethylated β-actin peptide Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6MEW Target: RFXANK Deposited: 07/09/2018 Human regulatory factor X associated ankyrin containing protein, ankyrin repeat, in complex with a RFX7 peptide Target Class: Miscellaneous Disease Areas: Signalling Site: Toronto Status: Follow-up official


	PDB: 6HK6 Target: RIOK2A Deposited: 05/09/2018 Human RIOK2 bound to inhibitor Target Class: Protein Kinase Disease Areas: Site: Oxford Status: Official


	PDB: 6HDP Target: DYRK2 Deposited: 18/08/2018 Human dual specificity tyrosine phosphorylation regulated kinase 2 Target Class: Protein Kinase/CMGC Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6HDR Target: DYRK2 Deposited: 18/08/2018 Human dual specificity tyrosine phosphorylation regulated kinase 2 Target Class: Protein Kinase/CMGC Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6EDF Target: FYN Deposited: 09/08/2018 Human FYN proto-oncogene, Src family tyrosine kinase, SH3 domain Target Class: Miscellaneous Disease Areas: Signalling Site: Toronto Status: Not counted


	PDB: 6GYN Target: HCN4A Deposited: 30/06/2018 CryoEM structure of HCN4 Target Class: Membrane proteins Disease Areas: Site: Oxford Status: Official


	PDB: 6GYO Target: HCN4A Deposited: 30/06/2018 CryoEM structure of HCN4 with bound cAMP Target Class: Membrane proteins Disease Areas: Site: Oxford Status: Official


	PDB: 6DXT Target: USP05 Deposited: 29/06/2018 Human ubiquitin specific peptidase 5, second ZnF domain, in complex with inhibitor DAT180 Target Class: Deubiquitinating Enzymes - USP, Ubiquitin Related Biology Disease Areas: Signalling and cancer Site: Toronto Status: MedChem


	PDB: 6GY5 Target: KLHL20A Deposited: 28/06/2018 Crystal structure of the kelch domain of human KLHL20 in complex with DAPK1 peptide Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 6DXH Target: USP05 Deposited: 28/06/2018 Human ubiquitin specific peptidase 5, second ZnF domain, in complex with inhibitor DAT201 Target Class: Deubiquitinating Enzymes - USP, Ubiquitin Related Biology Disease Areas: Signalling and cancer Site: Toronto Status: MedChem


	PDB: 6DVR Target: CARM1 Deposited: 25/06/2018 Human coactivator associated arginine methyltransferase 1, methyltransferase domain, in complex with inhibitor (R)-SKI-72 Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 6GWR Target: DDR1A Deposited: 25/06/2018 Structure of the DDR1 kinase domain in complex with a heterocycloalkynylbenzimide inhibitor Target Class: Kinase-TK Disease Areas: Site: Oxford Status:


	PDB: 6DUB Target: LOC149281 Deposited: 20/06/2018 Human Alpha N-terminal protein methyltransferase 11B (a.k.a NTM1B), methyltransferase domain, in complex with SPKRI peptide substrate Target Class: Methyltransferases Disease Areas: Signalling Site: Toronto Status: Follow-up official


	PDB: 6GTT Target: STK10A Deposited: 18/06/2018 Human STK10 bound to BIRB-796 Target Class: Protein Kinase/STE Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6GRU Target: NUDT5A Deposited: 12/06/2018 Crystal structure of human NUDT5 Target Class: NUDIX Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 6GR8 Target: AURKC Deposited: 10/06/2018 Human aurora kinase C Target Class: Protein Kinase/Other Disease Areas: Cancer Site: Oxford Status: Counted


	PDB: 6GR9 Target: AURKC Deposited: 10/06/2018 Human aurora kinase C Target Class: Protein Kinase/Other Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 6GRA Target: STK6 Deposited: 10/06/2018 Human aurora kinase A Target Class: Protein Kinase/Other Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6GQD Target: GALTA Deposited: 07/06/2018 Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L Target Class: Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 6GMB Target: HAO1A Deposited: 06/06/2018 Structure of human hydroxyacid oxidase 1 bound with FMN and glycolate Target Class: Oxidoreductases Disease Areas: Site: Oxford Status:


	PDB: 6GPJ Target: GMDSA Deposited: 06/06/2018 Crystal structure of human GDP-D-mannose 4,6-dehydratase in complex with GDP-4F-Man Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6GMC Target: HAO1A Deposited: 06/06/2018 1.2 A resolution structure of human hydroxyacid oxidase 1 bound with FMN and 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole Target Class: Oxidoreductases Disease Areas: Site: Oxford Status:


	PDB: 6GPL Target: GMDSA Deposited: 06/06/2018 Crystal structure of human GDP-D-mannose 4,6-dehydratase in complex with GDP-4k6d-Man Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6GPK Target: GMDSA Deposited: 06/06/2018 Crystal structure of human GDP-D-mannose 4,6-dehydratase (E157Q) in complex with GDP-Man Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 5QIB Target: HAO1A Deposited: 22/05/2018 Crystal Structure of HAO1 in complex with FMOPL000388a Target Class: Disease Areas: Site: Oxford Status:


	PDB: 5QHJ Target: FAM83BA Deposited: 18/05/2018 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000709a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 5QHK Target: FAM83BA Deposited: 18/05/2018 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000010a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 5QHO Target: FAM83BA Deposited: 18/05/2018 Crystal Structure of human FAM83B in complex with FMOPL000010a Target Class: Cell Division Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 5QHP Target: FAM83BA Deposited: 18/05/2018 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000554a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 5QHQ Target: FAM83BA Deposited: 18/05/2018 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000574a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 5QHR Target: FAM83BA Deposited: 18/05/2018 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000635a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 5QHI Target: FAM83BA Deposited: 18/05/2018 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000271a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 6GIN Target: ACVR1A Deposited: 14/05/2018 Crystal structure of the ACVR1 (ALK2) kinase in complex with an Quinazolinone based ALK2 inhibitor with a 4-morpholinophenyl solvent accessible group. Target Class: Protein Kinase/TKL Disease Areas: Site: Oxford Status:


	PDB: 6GIP Target: ACVR1A Deposited: 14/05/2018 Crystal structure of the ACVR1 (ALK2) kinase in complex with a Quinazolinone based ALK2 inhibitor with a 2, 5-dimethyl core. Target Class: Protein Kinase/TKL Disease Areas: Site: Oxford Status:


	PDB: 6GES Target: MAPK3A Deposited: 27/04/2018 Crystal structure of ERK1 covalently bound to SM1-71 Target Class: Protein Kinase/CMGC Disease Areas: Signalling and cancer Site: Frankfurt Status: Follow-up not counted


	PDB: 6D1T Target: MBD1 Deposited: 12/04/2018 Human methyl-CpG binding domain protein 1, MBD domain, in complex with methylated DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 6G57 Target: KCTD8A Deposited: 29/03/2018 Structure of the H1 domain of human KCTD8 Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Site: Oxford Status: Official


	PDB: 6G5N Target: SP100A Deposited: 29/03/2018 Crystal structure of human SP100 in complex with bromodomain-focused fragment XS039818e 1-(3-Phenyl-1,2,4-oxadiazol-5-yl)methanamine Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 6G5P Target: SP100A Deposited: 29/03/2018 Crystal structure of human SP100 in complex with bromodomain-focused fragment FM009493b 2,3-Dimethoxy-2,3-dimethyl-2,3-dihydro-1,4-benzodioxin-6-amine Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 6CVZ Target: RFWD3 Deposited: 29/03/2018 Human ring finger and WD repeat domain 3, WDR domain Target Class: WDR Disease Areas: Signalling and cancer Site: Toronto Status: Official


	PDB: 6CW0 Target: PP-BRD13 Deposited: 29/03/2018 Cryptosporidium parvum bromodomain containing protein 13 (cgd2_2690), in complex with inhibitor BI-2536 Target Class: Bromodomain Disease Areas: Parasitic disease Site: Status: Counted


	PDB: 6G54 Target: MAPK1A Deposited: 29/03/2018 Crystal structure of ERK2 covalently bound to SM1-71 Target Class: Protein Kinase/CMGC Disease Areas: Signalling and cancer Site: Frankfurt Status: Follow-up not counted


	PDB: 6D2L Target: CARM1 Deposited: 29/03/2018 Human coactivator associated arginine methyltransferase 1, methyltransferase domain, in complex with inhibitor (S)-SKI-72 Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6CCG Target: MBD3 Deposited: 29/03/2018 Human methyl-CpG binding domain protein 3, MBD domain, in complex with methylated CpG DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6CUI Target: BRD2 Deposited: 28/03/2018 Human bromodomain-containing protein 2, Extraterminal (ET) Domain Target Class: Bromodomain Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6G4Q Target: XX01SUCLG1A Deposited: 28/03/2018 Structure of human ADP-forming succinyl-CoA ligase complex SUCLG1-SUCLA2 Target Class: Disease Areas: Site: Oxford Status: Official


	PDB: 6G0P Target: BRD4A Deposited: 19/03/2018 Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated E2F1 peptide (K117ac/K120ac) Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6G0Q Target: BRD4A Deposited: 19/03/2018 Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated GATA1 peptide (K312ac/K315ac) Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6G0R Target: BRD4A Deposited: 19/03/2018 Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated POLR2A peptide (K775ac/K778ac) Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6G0S Target: BRD4A Deposited: 19/03/2018 Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated SIRT7 peptide (K272ac/K275ac) Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6G0O Target: BRD4A Deposited: 19/03/2018 Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated ATRX peptide (K1030ac/K1033ac) Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6CNP Target: MBD2 Deposited: 08/03/2018 Human methyl-CpG binding domain protein 2, MBD domain, in complex with CpG island Target Class: Miscellaneous Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6FWZ Target: DPAGT1A Deposited: 07/03/2018 Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant) in complex with UDP-GlcNAc Target Class: Membrane proteins Disease Areas: Neurobiology Site: Oxford Status: Follow-up official


	PDB: 6FU5 Target: RIPK2 Deposited: 28/02/2018 Human receptor interacting serine/threonine kinase 2 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6CKN Target: MLLT10 Deposited: 28/02/2018 Human histone methyltransferase cofactor AF-10, OM-LZ domain Target Class: Miscellaneous Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6CKO Target: MLLT10 - DOT1L Deposited: 28/02/2018 Human histone methyltransferase cofactor AF-10, OM-LZ domain, in complex with DOT1L coiled-coil domain Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 5QHL Target: FAM83BA Deposited: 18/02/2018 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000551a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 6CDG Target: GID4 Deposited: 08/02/2018 Human glucose-induced degradation protein 4 homolog, substrate binding domain, in complex with substrate peptide PGLWKS Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Signalling and metabolism Site: Toronto Status: Counted


	PDB: 6CCR Target: GID4 Deposited: 07/02/2018 Human glucose-induced degradation protein 4 homolog, substrate binding domain Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Signalling and metabolism Site: Toronto Status: Counted


	PDB: 6CC8 Target: MBD3 Deposited: 06/02/2018 Human methyl-CpG binding domain protein 3, MBD domain, in complex with methylated CpG DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Counted


	PDB: 6C1T Target: MBD2 Deposited: 05/01/2018 Human methyl-CpG binding domain protein 2, MBD domain, in complex with partially methylated DNA Target Class: Miscellaneous Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6C1V Target: MBD2 Deposited: 05/01/2018 Human methyl-CpG binding domain protein 2, MBD domain, in complex with double-stranded DNA Target Class: Miscellaneous Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6C1A Target: MBD2 Deposited: 04/01/2018 Human methyl-CpG binding domain protein 2, MBD domain, in complex with methylated DNA Target Class: Miscellaneous Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6FDY Target: ULK3 Deposited: 31/12/2017 Human unc-51 like kinase 3 Target Class: Protein Kinase/Other Disease Areas: Cancer Site: Oxford Status: Counted


	PDB: 6FDZ Target: ULK3 Deposited: 31/12/2017 Human unc-51 like kinase 3 Target Class: Protein Kinase/Other Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 6FCX Target: MTHFRA Deposited: 21/12/2017 Structure of human 5,10-methylenetetrahydrofolate reductase (MTHFR) Target Class: Disease Areas: Site: Oxford Status: Official


	PDB: 6BYA Target: PP-BRD3 Deposited: 20/12/2017 Leishmania donovani bromodomain containing 3 (LdBPK_091320), bromodomain, in complex with inhibitor SGC-CBP30 Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 6BY9 Target: EHMT1 Deposited: 20/12/2017 Human euchromatic histone lysine methyltransferase 1, ankyrin repeat Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Counted


	PDB: 6BYB Target: L3MBTL1 Deposited: 20/12/2017 Human L3MBTL1, histone methyl-lysine binding protein, MBT domains, in complex with inhibitor MBK14970 Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 6FBK Target: WNK2A Deposited: 19/12/2017 Crystal structure of the human WNK2 CCT-like 1 domain in complex with a WNK1 RFXV peptide Target Class: Protein Kinase/Other Disease Areas: Site: Oxford Status:


	PDB: 6BW3 Target: RBBP4 Deposited: 14/12/2017 Human RB binding protein 4, chromatin remodeling factor, WDR domain, in complex with PRDM3 peptide Target Class: WDR Disease Areas: Cancer and epigenetics Site: Status: Follow-up official


	PDB: 6BW4 Target: RBBP4 Deposited: 14/12/2017 Human RB binding protein 4, chromatin remodeling factor, WDR domain, in complex with PRDM16 peptide Target Class: WDR Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 6BPI Target: SETDB1 Deposited: 23/11/2017 Human histone-lysine N-methyltransferase SETDB1, triple Tudor domain, in complex with aryl triazole fragment peptide conjugate Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6EI2 Target: B2MA Deposited: 10/11/2017 Crystal Structure of HLA-A68 presenting a C-terminally extended peptide Target Class: Disease Areas: Site: Oxford Status:


	PDB: 6BHH Target: SETDB1 Deposited: 30/10/2017 Human histone-lysine N-methyltransferase SETDB1 W358A, triple Tudor domain, in complex with H3K9me2K14ac peptide Target Class: Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 6BHE Target: SETDB1 Deposited: 30/10/2017 Human histone-lysine N-methyltransferase SETDB1, triple Tudor domain, in complex with H3K9me3K14ac peptide Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 6BHG Target: SETDB1 Deposited: 30/10/2017 Human histone-lysine N-methyltransferase SETDB1, triple Tudor domain, in complex with H3K14ac peptide Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 6BHD Target: SETDB1 Deposited: 30/10/2017 Human histone-lysine N-methyltransferase SETDB1, triple Tudor domain, in complex with H3K9me2K14ac peptide Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6BHI Target: SETDB1 Deposited: 30/10/2017 Human histone-lysine N-methyltransferase SETDB1 W358A, triple Tudor domain, in complex with H3K9me3K14ac peptide Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6ES0 Target: RIPK2A Deposited: 19/10/2017 Crystal structure of the kinase domain of human RIPK2 in complex with the activation loop targeting inhibitor CS-R35 Target Class: Kinase-Other Disease Areas: Site: Oxford Status:


	PDB: 6EIM Target: STK10 Deposited: 18/10/2017 Human serine/threonine kinase 10 Target Class: Protein Kinase/STE Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6ASB Target: FBXL19 Deposited: 30/09/2017 Human F-box/LRR-repeat protein 19, CXXC and PHD finger domains, in complex with DNA Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Signalling and epigenetics Site: Toronto Status: Counted


	PDB: 6EIN Target: JARID1BA Deposited: 29/09/2017 Human lysine demethylase 5B Target Class: Demethylase/Methyl-Lysine Reader, PHD domain Disease Areas: Cancer Site: Oxford Status:


	PDB: 6EIU Target: JARID1BA Deposited: 29/09/2017 Human lysine demethylase 5B Target Class: Demethylase/Methyl-Lysine Reader, PHD domain Disease Areas: Cancer Site: Oxford Status:


	PDB: 6EIY Target: JARID1BA Deposited: 29/09/2017 Human lysine demethylase 5B Target Class: Demethylase/Methyl-Lysine Reader, PHD domain Disease Areas: Cancer Site: Oxford Status:


	PDB: 6EJ0 Target: JARID1BA Deposited: 29/09/2017 Human lysine demethylase 5B Target Class: Demethylase/Methyl-Lysine Reader, PHD domain Disease Areas: Cancer Site: Oxford Status:


	PDB: 6B57 Target: TDRD2 Deposited: 29/09/2017 Human Tudor and KH domain-containing protein, extended Tudor domain, in complex with glycine-arginine rich peptide Target Class: Methyl-lysine readers Disease Areas: Signalling and cancer Site: Toronto Status: Follow-up official


	PDB: 6EJ1 Target: JARID1BA Deposited: 29/09/2017 Human lysine demethylase 5B Target Class: Demethylase/Methyl-Lysine Reader, PHD domain Disease Areas: Cancer Site: Oxford Status:


	PDB: 6EK6 Target: JARID1BA Deposited: 29/09/2017 Human lysine demethylase 5B Target Class: Demethylase/Methyl-Lysine Reader, PHD domain Disease Areas: Cancer Site: Oxford Status:


	PDB: 6EKK Target: DENND1AA Deposited: 29/09/2017 Human DENN domain containing 1A Target Class: Disease Areas: Neurobiology Site: Oxford Status: Official


	PDB: 6EL8 Target: FOXN1A Deposited: 29/09/2017 Human transcription factor [Homo sapiens] Target Class: Disease Areas: Site: Oxford Status:


	PDB: 6ELM Target: WNK2A Deposited: 29/09/2017 Human WNK lysine deficient protein kinase 2 Target Class: Protein Kinase/Other Disease Areas: Site: Oxford Status:


	PDB: 6ASD Target: TET1 Deposited: 28/09/2017 Human methylcytosine dioxygenase TET1, CXXC domain, in complex with DNA Target Class: Miscellaneous Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6AU2 Target: SETDB1 Deposited: 28/09/2017 Human histone-lysine N-methyltransferase SETDB1, triple Tudor domain, in complex with aryl triazole fragment Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Status: Follow-up not counted


	PDB: 6AU3 Target: SETDB1 Deposited: 28/09/2017 Human histone-lysine N-methyltransferase SETDB1, triple Tudor domain, in complex with aryl triazole fragment Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6EIX Target: ACVR1Z Deposited: 19/09/2017 Mouse activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Site: Oxford Status:


	PDB: 5OY6 Target: ACVR1A Deposited: 08/09/2017 Human activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Site: Oxford Status:


	PDB: 5OXG Target: ACVR1A Deposited: 07/09/2017 Human activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Site: Oxford Status:


	PDB: 5YBJ Target: KANK1 Deposited: 05/09/2017 Human KN motif and ankyrin repeat domains 1, ankyrin repeat Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 5YBU Target: KANK1 Deposited: 05/09/2017 Human KN motif and ankyrin repeat domains 1, ankyrin repeat, in complex with KIF21A peptide Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 5YBV Target: KANK2 Deposited: 05/09/2017 Human KN motif and ankyrin repeat domains 2, ankyrin repeat, in complex with KIF21A peptide Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Follow-up not counted


	PDB: 5OWQ Target: STK10A Deposited: 03/09/2017 Human serine/threonine kinase 10 Target Class: Protein Kinase/STE Disease Areas: Site: Oxford Status:


	PDB: 5OWR Target: STK10A Deposited: 03/09/2017 Human serine/threonine kinase 10 Target Class: Protein Kinase/STE Disease Areas: Site: Oxford Status:


	PDB: 5WP3 Target: EED Deposited: 03/08/2017 Human Polycomb protein EED, in complex with EB22 Target Class: WDR Disease Areas: Cancer and epigenetics Site: Status: Follow-up official


	PDB: 5OCN Target: FOXN1A Deposited: 03/07/2017 Human transcription factor [Homo sapiens] Target Class: Disease Areas: Site: Oxford Status: Official


	PDB: 5WBV Target: SUV420H1 Deposited: 30/06/2017 Human Histone-lysine N-methyltransferase KMT5B (SUV420H1), catalytic domain, in complex with inhibitor Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 5WCJ Target: METTL13 Deposited: 30/06/2017 Human Methyltransferase-like protein 13, C-term catalytic domain, in complex with cofactor Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Counted


	PDB: 5WCI Target: MYST1 Deposited: 30/06/2017 Human histone acetyltransferase KAT8 (MYST1), catalytic domain, in complex with propionyl-coA Target Class: Transferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5WCG Target: SMYD2 Deposited: 30/06/2017 Human N-lysine methyltransferase SMYD2, full length, in complex with bi-subtrate inhibitor Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 5OCH Target: ABCB8A Deposited: 30/06/2017 Human ATP binding cassette subfamily B member 8 Target Class: IMP/ABC Transporter Disease Areas: Metabolism Site: Oxford Status: Official


	PDB: 5WBN Target: HDAC6 Deposited: 30/06/2017 Human histone deacetylase 6, ZnF ubiquitin-binding domain, in complex with inhibitor Target Class: Transferases, Ubiquitin Related Biology Disease Areas: Cancer Site: Toronto Status: Follow-up official


	PDB: 5W9S Target: CXXC5 Deposited: 30/06/2017 Human CXXC-type zinc finger protein 5, CXXC domain, in complex with DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Counted


	PDB: 5W9Q Target: MBD1 Deposited: 30/06/2017 Human Methyl-CpG-binding domain protein 1, 3rd CXXC domain, in complex with DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Official


	PDB: 5WCF Target: HRMT1L6 Deposited: 29/06/2017 Human protein arginine methyltransferase 6, catalytic domain, in complex with inhibitor Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 5OC9 Target: TMEM16KA Deposited: 29/06/2017 Human anoctamin 10 Target Class: IMP/Channel-Cl Disease Areas: Signalling Site: Oxford Status: Official


	PDB: 5W9R Target: PP-CDPK4 Deposited: 23/06/2017 Toxplasma gondii calmodulin-domain protein kinase 1 in complex with inhibitor LJQ138 Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5W9E Target: PP-CDPK4 Deposited: 23/06/2017 Toxplasma gondii calmodulin-domain protein kinase 1 in complex with inhibitor GXJ-186 Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5W91 Target: PP-CDPK4 Deposited: 22/06/2017 Toxplasma gondii calmodulin-domain protein kinase 1 in complex with inhibitor LZH-118 Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5W8R Target: PP-CDPK4 Deposited: 22/06/2017 Toxplasma gondii calmodulin-domain protein kinase 1 in complex with inhibitor 3CIB-PPI Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5W80 Target: PP-CDPK4 Deposited: 21/06/2017 Toxplasma gondii calmodulin-domain protein kinase 1 in complex with inhibitor GXJ-237 Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Status: Follow-up official


	PDB: 5W1Y Target: SETD8 Deposited: 05/06/2017 Human N-lysine methyltransferase KMT5A in complex with a covalent inhibitor Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 5NZW Target: DCLRE1AA Deposited: 02/06/2017 Human DNA cross-link repair 1A Target Class: RNA/DNA Processing/DNA-Repair Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5NZX Target: DCLRE1AA Deposited: 02/06/2017 Human DNA cross-link repair 1A Target Class: RNA/DNA Processing/DNA-Repair Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5NZY Target: DCLRE1AA Deposited: 02/06/2017 Human DNA cross-link repair 1A Target Class: RNA/DNA Processing/DNA-Repair Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5O5E Target: DPAGT1A Deposited: 01/06/2017 Human dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 Target Class: IMP/Enzyme Disease Areas: Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5NXC Target: LIMK1A Deposited: 25/05/2017 Human LIM domain kinase 1 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5NXD Target: LIMK2A Deposited: 25/05/2017 Human LIM domain kinase 2 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5O33 Target: XX02KALRNA Deposited: 24/05/2017 Human A structure of the GEF Kalirin DH1 domain in complex with the small GTPase Rac1 Target Class: Disease Areas: Signalling Site: Oxford Status: Official


	PDB: 5O2D Target: PARP14A Deposited: 20/05/2017 Human poly(ADP-ribose) polymerase family member 14 Target Class: Disease Areas: Metabolism Site: Oxford Status: Official


	PDB: 5O2C Target: WNK3B Deposited: 20/05/2017 Human WNK lysine deficient protein kinase 3 Target Class: Protein Kinase/Other Disease Areas: Signalling Site: Oxford Status: Official


	PDB: 5O1V Target: WNK3B Deposited: 20/05/2017 Human WNK lysine deficient protein kinase 3 Target Class: Protein Kinase/Other Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5O21 Target: WNK3B Deposited: 20/05/2017 Human WNK lysine deficient protein kinase 3 Target Class: Protein Kinase/Other Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5O23 Target: WNK3B Deposited: 20/05/2017 Human WNK lysine deficient protein kinase 3 Target Class: Protein Kinase/Other Disease Areas: Signalling Site: Oxford Status: Official


	PDB: 5O26 Target: WNK3B Deposited: 20/05/2017 Human WNK lysine deficient protein kinase 3 Target Class: Protein Kinase/Other Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5O2B Target: WNK3B Deposited: 20/05/2017 Human WNK lysine deficient protein kinase 3 Target Class: Protein Kinase/Other Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5O1N Target: AASSA Deposited: 19/05/2017 Human aminoadipate-semialdehyde synthase Target Class: Oxidoreductases Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 5O1O Target: AASSA Deposited: 19/05/2017 Human aminoadipate-semialdehyde synthase Target Class: Oxidoreductases Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 5O1P Target: AASSA Deposited: 19/05/2017 Human aminoadipate-semialdehyde synthase Target Class: Oxidoreductases Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 5VS7 Target: PP-BRD4 Deposited: 11/05/2017 Plasmodium falciparum bromodomain protein 3 (PF3D7_1475600), bromodomain, in complex with H4K5ac peptide Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 5NNC Target: BRD4 Deposited: 19/04/2017 Human bromodomain containing 4 Target Class: Bromodomain Disease Areas: Cancer and epigenetics Site: Oxford Status: MedChem


	PDB: 5NND Target: BRD4 Deposited: 19/04/2017 Human bromodomain containing 4 Target Class: Bromodomain Disease Areas: Cancer and epigenetics Site: Oxford Status: MedChem


	PDB: 5NNE Target: BRD4 Deposited: 19/04/2017 Human bromodomain containing 4 Target Class: Bromodomain Disease Areas: Cancer and epigenetics Site: Oxford Status: MedChem


	PDB: 5NNF Target: BRD4 Deposited: 19/04/2017 Human bromodomain containing 4 Target Class: Bromodomain Disease Areas: Cancer and epigenetics Site: Oxford Status: MedChem


	PDB: 5NNG Target: BRD4 Deposited: 19/04/2017 Human bromodomain containing 4 Target Class: Bromodomain Disease Areas: Cancer and epigenetics Site: Oxford Status: MedChem


	PDB: 5NKS Target: DPYSL4A Deposited: 31/03/2017 Human dihydropyrimidinase like 4 Target Class: Disease Areas: Neurobiology Site: Oxford Status: Official


	PDB: 5NLB Target: XX09KEAP1A Deposited: 31/03/2017 5NLB Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Metabolism Site: Oxford Status: Official


	PDB: 5NKP Target: KLHL3A Deposited: 31/03/2017 Human kelch like family member 3 (KLHL3) in complex with WNK3 peptide Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 5VC9 Target: CXXC4 Deposited: 29/03/2017 CXXC finger protein 4, Zinc finger, in complex with ACGT DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Official


	PDB: 5VC8 Target: WHSC1 Deposited: 29/03/2017 Human nuclear receptor binding SET domain protein 2, first PWWP domain Target Class: Methyl-lysine readers Disease Areas: Cancer Site: Toronto Status: Official


	PDB: 5VBT Target: UBC Deposited: 29/03/2017 Human ubiquitin variant UBH04 Target Class: Ubiquitin Related Biology Disease Areas: Signalling Site: Toronto Status: Follow-up official


	PDB: 5VBB Target: RPUSD1 Deposited: 28/03/2017 Human RNA pseudouridylate synthase domain containing 1, catalytic domain Target Class: Oxidoreductases Disease Areas: Signalling Site: Toronto Status: Official


	PDB: 5VBD Target: USP09X Deposited: 28/03/2017 Human ubiquitin specific peptidase 9, X-linked, ubiquitin-like domain Target Class: Deubiquitinating Enzymes - USP, Ubiquitin Related Biology Disease Areas: Signalling Site: Toronto Status: Official


	PDB: 5V9J Target: EHMT1 Deposited: 23/03/2017 Human euchromatic histone lysine methyltransferase 1, catalytic domain, in complex with inhibitor MS0105 Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5V9I Target: BAT8 Deposited: 23/03/2017 Human euchromatic histone lysine methyltransferase 2, catalytic domain, in complex with inhibitor UNC3644 Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5NFJ Target: RG9MTD1A Deposited: 14/03/2017 Human tRNA methyltransferase 10C, mitochondrial RNase P subunit Target Class: Metabolic enzymes/Other Disease Areas: Metabolism Site: Oxford Status: Official


	PDB: 5MXX Target: SRPK1A Deposited: 07/02/2017 Human SRSF protein kinase 1 Target Class: Protein Kinase/CMGC Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5MYG Target: BRPF1B Deposited: 07/02/2017 Human bromodomain and PHD finger containing 1 Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up not counted


	PDB: 5N2L Target: BRD2A Deposited: 07/02/2017 Human bromodomain containing 2 Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5MYV Target: SRPK2A Deposited: 29/01/2017 Human SRSF protein kinase 2 Target Class: Protein Kinase/CMGC Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5MY8 Target: SRPK1A Deposited: 25/01/2017 Human SRSF protein kinase 1 Target Class: Protein Kinase/CMGC Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5ULO Target: YWHAZ Deposited: 25/01/2017 Human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta, in complex with a TBC1D7 phosphopeptide Target Class: Signalling proteins Disease Areas: Metabolism Site: Toronto Status: Follow-up official


	PDB: 5MUF Target: PGAM5A Deposited: 13/01/2017 Human PGAM family member 5, mitochondrial serine/threonine protein phosphatase Target Class: Phosphatases Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5UBA Target: RPUSD4 Deposited: 30/12/2016 Human RNA pseudouridylate synthase domain containing 4, catalytic domain Target Class: Transferases Disease Areas: Chromatin and epigenetics, Signalling Site: Toronto Status: Pending-Official Structure


	PDB: 5UBB Target: LOC149281 Deposited: 30/12/2016 Human methyltransferase like 11B (a.k.a NTM1B), catalytic domain, in complex with cofactor SAM Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics, Signalling Site: Toronto Status: Pending-Official Structure


	PDB: 5MR8 Target: TRIM33B Deposited: 28/12/2016 Human tripartite motif containing 33 Target Class: Bromodomain, Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Official


	PDB: 5MR1 Target: PIP3EA Deposited: 21/12/2016 Human interaction protein for cytohesin exchange factors 1 Target Class: Miscellaneous Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5MQ4 Target: PRKCBP1A Deposited: 20/12/2016 Human zinc finger MYND-type containing 8 Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Pending-Official Structure


	PDB: 5MQ1 Target: BRD7A Deposited: 19/12/2016 Human bromodomain containing 7 Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5MPO Target: XX02MOCS2A Deposited: 16/12/2016 Human molybdenum cofactor synthesis 2 Target Class: Miscellaneous Disease Areas: Neurobiology Site: Oxford Status: Pending-Official Structure


	PDB: 5U9N Target: PP-BRD3 Deposited: 16/12/2016 Cryptosporidium parvum cdg4_1340, second bromodomain, in complex with bromosporine Target Class: Bromodomain Disease Areas: Chromatin and epigenetics, Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5MP0 Target: DCP2B Deposited: 15/12/2016 Human decapping mRNA 2 Target Class: NUDIX Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5MLE Target: DPYSL2A Deposited: 06/12/2016 Human dihydropyrimidinase like 2 Target Class: Miscellaneous Disease Areas: Neurobiology Site: Oxford Status: Pending-Official Structure


	PDB: 5U4X Target: CARM1 Deposited: 06/12/2016 Human coactivator associated arginine methyltransferase 1, catalytic domain, in complex with chemical probe TP-064 Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 5MKV Target: DPYSL2A Deposited: 05/12/2016 Human dihydropyrimidinase like 2 Target Class: Miscellaneous Disease Areas: Neurobiology Site: Oxford Status: Pending-Official Structure


	PDB: 5MG2 Target: TAF1A Deposited: 20/11/2016 Human TATA-box binding protein associated factor 1 Target Class: Bromodomain Disease Areas: Cancer, Signalling Site: Oxford Status: Follow-up official


	PDB: 5TB6 Target: CREBBP Deposited: 09/11/2016 Human CREB binding protein isoform a Target Class: Bromodomain Disease Areas: Cancer, Metabolism, Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5TTW Target: EED Deposited: 04/11/2016 Human embryonic ectoderm development, WDR domain, in complex with peptoid inhibitor UNC4859 Target Class: WDR Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 5TTF Target: BAT8 Deposited: 03/11/2016 Human euchromatic histone lysine methyltransferase 2, catalytic domain, in complex with inhibitor MS012 Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics, Neurobiology Site: Toronto Status: Follow-up not counted


	PDB: 5TTG Target: EHMT1 Deposited: 03/11/2016 Human euchromatic histone lysine methyltransferase 1, catalytic domain, in complex with inhibitor MS012 Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5M9N Target: TDRD1A Deposited: 01/11/2016 Human tudor domain containing 1 Target Class: Methyl-lysine readers Disease Areas: Site: Oxford Status: Pending-Official Structure


	PDB: 5M9O Target: SND1A Deposited: 01/11/2016 Human staphylococcal nuclease and tudor domain containing 1 Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5TPX Target: PF08_0034 Deposited: 24/10/2016 Plasmodium falciparum histone acetyltransferase GCN5, bromodomain, in complex with inhibitor L-45/L-Moses Target Class: Bromodomain Disease Areas: Chromatin and epigenetics, Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 5T4U Target: BRPF1B Deposited: 01/10/2016 Human bromodomain and PHD finger containing 1 Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5T4V Target: BRPF1B Deposited: 01/10/2016 Human bromodomain and PHD finger containing 1 Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5TEY Target: METTL3-METTL14 Deposited: 30/09/2016 Human methyltransferase like 3 - 14 dimer in complex with cofactor Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5TH7 Target: SETD8 Deposited: 30/09/2016 Human SET domain containing (lysine methyltransferase) 8, SET domain, in complex with covalent inhibitor MS453 Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 5LZK Target: FAM83BA Deposited: 29/09/2016 Human family with sequence similarity 83 member B Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Pending-Official Structure


	PDB: 5GXH Target: GEMIN5 Deposited: 25/09/2016 Human gem nuclear organelle associated protein 5, WD40 domain, in complex with AAUUUUUG RNA Target Class: WDR Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5GXI Target: GEMIN5 Deposited: 25/09/2016 Human gem nuclear organelle associated protein 5, WD40 domain, in complex with AAUUUUUGAG RNA Target Class: WDR Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 5TEE Target: GEMIN5 Deposited: 23/09/2016 Human gem nuclear organelle associated protein 5, WD40 domain Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Pending-Official Structure


	PDB: 5TEF Target: GEMIN5 Deposited: 23/09/2016 Human gem nuclear organelle associated protein 5, WD40 domain, in complex with m7GpppG Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 5TF2 Target: PREB Deposited: 23/09/2016 Human prolactin regulatory element binding protein, WD40 domain Target Class: Miscellaneous Disease Areas: Neurobiology Site: Toronto Status: Pending - Official structure


	PDB: 5THA Target: GEMIN5 Deposited: 23/09/2016 Human gem nuclear organelle associated protein 5, WD40 domain, in complex with GTP Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5LXC Target: DYRK2A Deposited: 20/09/2016 Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer, Metabolism, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5LXD Target: DYRK2A Deposited: 20/09/2016 Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer, Metabolism, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5LWN Target: JAK3A Deposited: 18/09/2016 Human Janus kinase 3 (a protein tyrosine kinase, leukocyte) Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5LWM Target: JAK3A Deposited: 18/09/2016 Human Janus kinase 3 (a protein tyrosine kinase, leukocyte) Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5LTU Target: NUDT4A Deposited: 16/09/2016 Human nudix hydrolase 4 Target Class: NUDIX Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5LW9 Target: JARID1BA Deposited: 15/09/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5TCK Target: PP-BRD3 Deposited: 15/09/2016 Leishmania donovani LdBPK.091320, second bromodomain, in complex with Bromosporine Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5TCM Target: PP-BRD3 Deposited: 15/09/2016 Leishmania donovani LdBPK.091320, first bromodomain, in complex with BI-2536 Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5LVQ Target: PCAFA Deposited: 14/09/2016 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5LVR Target: PCAFA Deposited: 14/09/2016 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5LUU Target: BRD4A Deposited: 11/09/2016 Human bromodomain containing 4 [isoform long] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5LUG Target: SPIN2BA Deposited: 09/09/2016 Human spindlin family member 2B Target Class: Chromatin Regulation Disease Areas: Chromatin and epigenetics Site: Oxford Status: Pending-Official Structure


	PDB: 5T5G Target: SETD8 Deposited: 30/08/2016 Human SET domain containing (lysine methyltransferase) 8, SET domain, in complex with inhibitor MS2177 Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 5T3P Target: NUDT7A Deposited: 26/08/2016 Human nudix hydrolase 7 Target Class: NUDIX Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5T1G Target: CBX1 Deposited: 19/08/2016 Human chromobox 1, chromoshadow domain, in complex with a histone 3 peptide Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5T1I Target: CBX3 Deposited: 19/08/2016 Human chromobox 3, chromoshadow domain, in complex with a histone 3 peptide Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 5LEV Target: DPAGT1A Deposited: 30/06/2016 Human dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 Target Class: IMP/Enzyme Disease Areas: Metabolism Site: Oxford Status: Official


	PDB: 5LF8 Target: NUDT17A Deposited: 30/06/2016 Human nudix (nucleoside diphosphate linked moiety X)-type motif 17 Target Class: Nucleotide metabolism, NUDIX Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5KO4 Target: PP-BRD19 Deposited: 29/06/2016 Trypanosoma brucei bromodomain containing factor 1 (Tb427.10.8150), Bromodomain Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Pending - Official structure


	PDB: 5KO9 Target: tesst Deposited: 29/06/2016 Human 5-hydroxymethylcytosine (hmC) binding, ES cell-specific, SRAP domain Target Class: Miscellaneous Disease Areas: Site: Oxford Status: Pending - Official structure


	PDB: 5KKP Target: PUS7 Deposited: 22/06/2016 Human pseudouridylate synthase 7, catalytic domain Target Class: Transferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Pending - Official structure


	PDB: 5LB3 Target: RECQL5A Deposited: 15/06/2016 Human RecQ protein-like 5 [isoform 1] Target Class: DExD-DExH RNA helicases Disease Areas: Cancer Site: Oxford Status: Pending-Official Structure


	PDB: 5LB5 Target: RECQL5A Deposited: 15/06/2016 Human RecQ protein-like 5 [isoform 1] Target Class: DExD-DExH RNA helicases Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5LB8 Target: RECQL5A Deposited: 15/06/2016 Human RecQ protein-like 5 [isoform 1] Target Class: DExD-DExH RNA helicases Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5LBA Target: RECQL5A Deposited: 15/06/2016 Human RecQ protein-like 5 [isoform 1] Target Class: DExD-DExH RNA helicases Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5B8D Target: HDAC6 Deposited: 14/06/2016 Human histone deacetylase 6, Znf ubiquitin binding domain, in complex with x304 (N-(4-Methyl-1,3-thiazol-2-yl)propanamide) in secondary pocket Target Class: Transferases, Ubiquitin Related Biology Disease Areas: Cancer Site: Toronto Status: MedChem


	PDB: 5KH3 Target: HDAC6 Deposited: 14/06/2016 Human histone deacetylase 6, Znf ubiquitin binding domain, in complex with DAT94a (3-(5-Chloro-1,3-benzothiazol-2-yl)propanoic acid). Target Class: Ubiquitin Related Biology Disease Areas: Site: Toronto Status: MedChem


	PDB: 5KH6 Target: SETDB1 Deposited: 14/06/2016 Human SET domain bifurcated 1, triple Tudor domain, in complex with fragment x337 Target Class: Methyl-lysine readers Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Pending-Official Structure


	PDB: 5KH7 Target: HDAC6 Deposited: 14/06/2016 Human histone deacetylase 6, Znf ubiquitin binding domain, in complex with F1967-0912 (3-[6-Oxo-3-(3-pyridinyl)-1(6H)-pyridazinyl]propanoic acid) Target Class: Transferases, Ubiquitin Related Biology Disease Areas: Cancer Site: Toronto Status: MedChem


	PDB: 5KH9 Target: HDAC6 Deposited: 14/06/2016 Human histone deacetylase 6, Znf ubiquitin binding domain, in complex with x469 (5-[(4-Isopropylphenyl)amino]-6-methyl-1,2,4-triazin-3(2H)-one) Target Class: Transferases, Ubiquitin Related Biology Disease Areas: Cancer Site: Toronto Status: MedChem


	PDB: 5LAR Target: MAPK14A Deposited: 14/06/2016 Human mitogen-activated protein kinase 14 [isoform 1] Target Class: Protein Kinase Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5L76 Target: AASSA Deposited: 02/06/2016 Human aminoadipate-semialdehyde synthase Target Class: Oxidoreductases Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5L78 Target: AASSA Deposited: 02/06/2016 Human aminoadipate-semialdehyde synthase Target Class: Oxidoreductases Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5L6W Target: XX02LIMK1A Deposited: 31/05/2016 Human LIMK1-ATPgammaS-CFL1 Complex Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Pending-Official Structure


	PDB: 5J0D Target: CREBBPA Deposited: 30/05/2016 Human CREB binding protein Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics Site: Oxford Status: Pending-Official Structure


	PDB: 5L4Q Target: AAK1A Deposited: 26/05/2016 Human AP2 associated kinase 1 Target Class: Protein Kinase Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5K47 Target: PKD2A Deposited: 20/05/2016 Human polycystic kidney disease 2 (autosomal dominant) Target Class: Membrane proteins Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5K29 Target: PP-BRD3 Deposited: 18/05/2016 Trypanosoma brucei bromodomain containing factor 5 (Tb427tmp.01.5000), Bromodomain Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5JUW Target: DOT1L Deposited: 10/05/2016 Human DOT1 like histone lysine methyltransferase in complex with cyano-deaza-SAH Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5G3Q Target: WNK1A Deposited: 29/04/2016 Human WNK lysine deficient protein kinase 1 Target Class: Protein Kinase/Other Disease Areas: Cancer Site: Oxford Status: Pending-Official Structure


	PDB: 5JN2 Target: PP-CDPK4 Deposited: 29/04/2016 Toxoplasma gondii calcium dependent protein kinase 1, kinase domain, in complex with inhibitor NVPACU106 Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 5JJW Target: SART3 Deposited: 25/04/2016 Human squamous cell carcinoma antigen recognized by T-cells 3, HAT (Half-A-TPR) repeat, in complex with USP15 DUSP-UBL domain Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Pending-Official Structure


	PDB: 5JJX Target: SART3 Deposited: 25/04/2016 Human squamous cell carcinoma antigen recognized by T-cells 3, HAT (Half-A-TPR) repeat Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Pending-Official Structure


	PDB: 5FY7 Target: UTYC Deposited: 03/04/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5J3U Target: PP-PKAR Deposited: 31/03/2016 Toxoplasma gondii protein kinase A (583.m05422), regulatory domain, in complex with cAMP Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5J39 Target: TDRD2 Deposited: 30/03/2016 Human tudor and KH domain containing, extended tudor domain Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Pending-Official Structure


	PDB: 5J3E Target: THYN1 Deposited: 30/03/2016 Human thymocyte nuclear protein 1, EVE domain, in complex with 5-methylcytosine containing DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Pending-Official Structure


	PDB: 5J1V Target: CLK1A Deposited: 30/03/2016 Human CDC-like kinase 1 Target Class: Protein Kinase Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5J1W Target: CLK1A Deposited: 30/03/2016 Human CDC-like kinase 1 Target Class: Protein Kinase Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5HES Target: ZAKA Deposited: 23/03/2016 Human sterile-alpha motif and leucine zipper containing kinase AZK Target Class: Protein Kinase Disease Areas: Signalling Site: Oxford Status: Pending-Official Structure


	PDB: 5FZO Target: JMJD1CA Deposited: 15/03/2016 Human jumonji domain containing 1C [isoform a] Target Class: Oxidoreductases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZC Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZE Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Pending-Official Structure


	PDB: 5FZF Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZG Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZH Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZI Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZK Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZL Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZM Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZB Target: JARID1BA Deposited: 13/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZD Target: JARID1BA Deposited: 13/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZA Target: JARID1BA Deposited: 12/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ9 Target: JARID1BA Deposited: 12/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ6 Target: JARID1BA Deposited: 11/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ7 Target: JARID1BA Deposited: 11/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ8 Target: JARID1BA Deposited: 11/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYS Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYT Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYU Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYV Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYY Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYZ Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ0 Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ1 Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ3 Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ4 Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYM Target: UTYC Deposited: 08/03/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5IN3 Target: GALTA Deposited: 07/03/2016 Human galactose-1-phosphate uridylyltransferase Target Class: Transferases Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5FYC Target: JMJD2AA Deposited: 07/03/2016 Human jumonji domain containing 2A Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYH Target: JMJD2AA Deposited: 07/03/2016 Human jumonji domain containing 2A Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYI Target: JMJD2AA Deposited: 07/03/2016 Human jumonji domain containing 2A Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYB Target: JARID1BA Deposited: 05/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FY4 Target: JARID1BA Deposited: 04/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FY5 Target: JARID1BA Deposited: 04/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FY8 Target: JMJD2AA Deposited: 04/03/2016 Human jumonji domain containing 2A Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FY9 Target: JARID1BA Deposited: 04/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FXV Target: UTYC Deposited: 03/03/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5FXW Target: UTYC Deposited: 03/03/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5FXX Target: UTYC Deposited: 03/03/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5FXZ Target: UTYC Deposited: 03/03/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5FY0 Target: UTYC Deposited: 03/03/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5FY1 Target: UTYC Deposited: 03/03/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5II2 Target: PB1A Deposited: 01/03/2016 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5IID Target: PB1A Deposited: 01/03/2016 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5II1 Target: PB1A Deposited: 01/03/2016 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5IGN Target: BRD9A Deposited: 28/02/2016 Human bromodomain containing 9 [isoform 1] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FWJ Target: JARID1CA Deposited: 17/02/2016 Human Jumonji/ARID domain-containing protein 1C Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5I3L Target: DPF3 Deposited: 10/02/2016 Human double PHD fingers 3, double PHD domain, in complex with H3K14ac peptide Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5HZM Target: HRMT1L6 Deposited: 02/02/2016 Human protein arginine methyltransferase 6 with putative Rme2 electron density Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5FUN Target: JARID1BA Deposited: 28/01/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FUP Target: JARID1BA Deposited: 28/01/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FV3 Target: JARID1BA Deposited: 28/01/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5HRV Target: PB1A Deposited: 24/01/2016 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5HRW Target: PB1A Deposited: 24/01/2016 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5HRX Target: PB1A Deposited: 24/01/2016 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5H9M Target: SIAH2 Deposited: 28/12/2015 Human siah E3 ubiquitin protein ligase 2, TRAF-like substrate binding domain Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: Official


	PDB: 5FH8 Target: PB1A Deposited: 21/12/2015 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5FPL Target: JARID1BA Deposited: 21/12/2015 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FPU Target: JARID1BA Deposited: 21/12/2015 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FPV Target: JMJD2AA Deposited: 21/12/2015 Human jumonji domain containing 2A Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FH6 Target: PB1A Deposited: 21/12/2015 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5FH7 Target: PB1A Deposited: 21/12/2015 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5FG4 Target: BRPF1B Deposited: 20/12/2015 Human bromodomain and PHD finger-containing protein 1 [isoform 2] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FG5 Target: BRPF1B Deposited: 20/12/2015 Human bromodomain and PHD finger-containing protein 1 [isoform 2] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FG6 Target: BRD1A Deposited: 20/12/2015 Human bromodomain containing protein 1 Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FFV Target: BRPF1B Deposited: 19/12/2015 Human bromodomain and PHD finger-containing protein 1 [isoform 2] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FFW Target: BRPF1B Deposited: 19/12/2015 Human bromodomain and PHD finger-containing protein 1 [isoform 2] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FFY Target: BRPF1B Deposited: 19/12/2015 Human bromodomain and PHD finger-containing protein 1 [isoform 2] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FE3 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE4 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE5 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE6 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE7 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE8 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE9 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FEA Target: PP-BRD19 Deposited: 16/12/2015 Leishmania donovani bromodomain (LdBPK_363520.1), domain swapped, in complex with Bromosporine Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5FDP Target: DDR1A Deposited: 16/12/2015 Human discoidin domain receptor family, member 1 isoform b Target Class: Protein Kinase Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5FDX Target: DDR1A Deposited: 16/12/2015 Human discoidin domain receptor family, member 1 isoform b Target Class: Protein Kinase Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5FDZ Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE0 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE1 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE2 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FBX Target: BRD4A Deposited: 14/12/2015 Human bromodomain containing 4 [isoform long] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5FAI Target: EMG1 Deposited: 11/12/2015 Human EMG1 N1-specific pseudouridine methyltransferase, catalytic domain, in complex with S-adenosyl homocysteine Target Class: Transferases Disease Areas: Signalling Site: Toronto Status: Pending-Official Structure


	PDB: 5F5A Target: JMJD2DA Deposited: 04/12/2015 Human jumonji domain containing 2D Target Class: Oxidoreductases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5F5C Target: JMJD2DA Deposited: 04/12/2015 Human jumonji domain containing 2D Target Class: Oxidoreductases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5F5I Target: JMJD2AA Deposited: 04/12/2015 Human jumonji domain containing 2A Target Class: Oxidoreductases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5EQ0 Target: CBX8 Deposited: 12/11/2015 Human chromobox 8, chromodomain, in complex with inhibitor UNC3866 Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5EPJ Target: CBX7 Deposited: 11/11/2015 Human chromobox 7, chromodomain, in complex with inhibitor UNC3866 Target Class: Methyl-lysine readers Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5EPK Target: CBX2 Deposited: 11/11/2015 Human chromobox 2, chromodomain, in complex with inhibitor UNC3866 Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5EPL Target: CBX4 Deposited: 11/11/2015 Human chromobox 4, chromodomain, in complex with inhibitor UNC3866 Target Class: Methyl-lysine readers Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 5ENJ Target: PHIPA Deposited: 09/11/2015 Human pleckstrin homology domain interacting protein Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5ENB Target: PHIPA Deposited: 09/11/2015 Human pleckstrin homology domain interacting protein Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5ENC Target: PHIPA Deposited: 09/11/2015 Human pleckstrin homology domain interacting protein Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5ENE Target: PHIPA Deposited: 09/11/2015 Human pleckstrin homology domain interacting protein Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5ENF Target: PHIPA Deposited: 09/11/2015 Human pleckstrin homology domain interacting protein Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5ENH Target: PHIPA Deposited: 09/11/2015 Human pleckstrin homology domain interacting protein Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5ENI Target: PHIPA Deposited: 09/11/2015 Human pleckstrin homology domain interacting protein Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5EK9 Target: BRD2A Deposited: 03/11/2015 Human bromodomain containing 2 Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5EAL Target: WDR5 Deposited: 16/10/2015 Human WD repeat domain 5 in complex with chemical probe OICR-9429 analog 9h Target Class: Miscellaneous Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5EAM Target: WDR5 Deposited: 16/10/2015 Human WD repeat domain 5 in complex with chemical probe OICR-9429 analog 9o Target Class: Miscellaneous Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5EAP Target: WDR5 Deposited: 16/10/2015 Human WD repeat domain 5 in complex with chemical probe OICR-9429 analog 9e Target Class: Miscellaneous Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5EAR Target: WDR5 Deposited: 16/10/2015 Human WD repeat domain 5 in complex with chemical probe OICR-9429 analog 9d Target Class: Miscellaneous Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5E9V Target: BRD9A Deposited: 15/10/2015 Human bromodomain containing 9 [isoform 1] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5E8R Target: HRMT1L6 Deposited: 14/10/2015 Human protein arginine methyltransferase 6 in complex with chemical probe MS023 Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5E1O Target: AD-003 Deposited: 30/09/2015 Human N-terminal Xaa-Pro-Lys N-methyltransferase 1, in complex with cofactor SAH and RPKRIA peptide substrate Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: Follow-up not counted


	PDB: 5E2A Target: AD-003 Deposited: 30/09/2015 Human N-terminal Xaa-Pro-Lys N-methyltransferase 1, in complex with cofactor SAH and SmePKRIA peptide substrate Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: Follow-up not counted


	PDB: 5E2B Target: AD-003 Deposited: 30/09/2015 Human N-terminal Xaa-Pro-Lys N-methyltransferase 1, in complex with cofactor SAH and PmePKRIA peptide substrate Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: Follow-up not counted


	PDB: 5E26 Target: PANK2 Deposited: 30/09/2015 Human pantothenate kinase 2, catalytic domain, in complex with pantothenate and adenosine diphosphate Target Class: Non-protein Kinase Disease Areas: Metabolism, Signalling Site: Toronto Status: Pending-Official Structure


	PDB: 5E1B Target: AD-003 Deposited: 30/09/2015 Human N-terminal Xaa-Pro-Lys N-methyltransferase 1, in complex with cofactor SAH and SPKRIA peptide substrate Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: Pending-Official Structure


	PDB: 5E1D Target: AD-003 Deposited: 30/09/2015 Human N-terminal Xaa-Pro-Lys N-methyltransferase 1, in complex with cofactor SAH and YPKRIA peptide substrate Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: Follow-up official


	PDB: 5E1M Target: AD-003 Deposited: 30/09/2015 Human N-terminal Xaa-Pro-Lys N-methyltransferase 1, in complex with cofactor SAH and PPKRIA peptide substrate Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: Follow-up not counted


	PDB: 5E16 Target: PP-PKG Deposited: 29/09/2015 Plasmodium falciparum cGMP-dependent protein kinase (PF14_0346), N-terminal cGMP binding domain, in complex with cyclic GMP Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 5DVT Target: PP-CDPK4 Deposited: 25/09/2015 Toxoplasma gondii calcium dependent protein kinase 1, kinase domain, in complex with inhibitor SGC-1-19 Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5DZC Target: PP-PKG Deposited: 25/09/2015 Plasmodium vivax protein kinase G (PVX_084705) in complex with a AMP-PNP Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5FII Target: PAHA Deposited: 25/09/2015 Human phenylalanine hydroxylase Target Class: Amino oxidases Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5DVR Target: PP-CDPK4 Deposited: 21/09/2015 Toxoplasma gondii calcium dependent protein kinase 1, kinase domain, in complex with inhibitor GW780159X Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5DVU Target: PP-CDPK4 Deposited: 21/09/2015 Toxoplasma gondii calcium dependent protein kinase 1, kinase domain, in complex with inhibitor SGC-1-9 Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5APA Target: ASPHA Deposited: 16/09/2015 Human aspartate beta-hydroxylase isoform a; junctin isoform 1; junctate; aspartyl/asparaginyl-beta-hydroxylase; peptide-aspartate beta-dioxygenase; humbug Target Class: Amino oxidases Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5DKD Target: SMARCA4A Deposited: 03/09/2015 Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5DKH Target: SMARCA2B Deposited: 03/09/2015 Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5DKC Target: SMARCA2B Deposited: 03/09/2015 Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5ACB Target: XX05CRK7A Deposited: 14/08/2015 Human CDK12-Cyclin K complex with inhibitor Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CZG Target: PP-BRD18 Deposited: 31/07/2015 Trypanosoma brucei hypothetical bromodomain Tb427.10.7420, in complex with bromosporine Target Class: Bromodomain Disease Areas: Chromatin and epigenetics, Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5A7O Target: JMJD2AA Deposited: 24/07/2015 Human jumonji domain containing 2A Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5A7P Target: JMJD2AA Deposited: 24/07/2015 Human jumonji domain containing 2A Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5A7Q Target: JMJD2AA Deposited: 24/07/2015 Human jumonji domain containing 2A Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5A7S Target: JMJD2AA Deposited: 24/07/2015 Human jumonji domain containing 2A Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5A7W Target: JMJD2AA Deposited: 24/07/2015 Human jumonji domain containing 2A Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5A80 Target: JMJD2AA Deposited: 24/07/2015 Human jumonji domain containing 2A Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5CU8 Target: BAZ2BA Deposited: 24/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CUA Target: BAZ2BA Deposited: 24/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CUB Target: BAZ2BA Deposited: 24/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CUC Target: BAZ2BA Deposited: 24/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CUD Target: BAZ2BA Deposited: 24/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CUE Target: BAZ2BA Deposited: 24/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CUG Target: BAZ2BA Deposited: 24/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5A7N Target: JMJD2AA Deposited: 24/07/2015 Human jumonji domain containing 2A Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5A9F Target: POLQA Deposited: 21/07/2015 Human DNA polymerase theta [isoform 1] Target Class: Miscellaneous Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5A9J Target: POLQA Deposited: 21/07/2015 Human DNA polymerase theta [isoform 1] Target Class: Miscellaneous Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CQ3 Target: BAZ2BA Deposited: 21/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CQ4 Target: BAZ2BA Deposited: 21/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CQ5 Target: BAZ2BA Deposited: 21/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CQ6 Target: BAZ2BA Deposited: 21/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CQ7 Target: BAZ2BA Deposited: 21/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CQ8 Target: BAZ2BA Deposited: 21/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CQA Target: BAZ2BA Deposited: 21/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CLT Target: GBE1A Deposited: 16/07/2015 Human glucan (1,4-alpha-), branching enzyme 1 Target Class: Miscellaneous Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 5CLW Target: GBE1A Deposited: 16/07/2015 Human glucan (1,4-alpha-), branching enzyme 1 Target Class: Miscellaneous Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 5A6R Target: KCTD17A Deposited: 30/06/2015 Human BTB/POZ domain-containing protein KCTD17 Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Metabolism Site: Oxford Status: Official


	PDB: 5C96 Target: PTPN11 Deposited: 30/06/2015 Human protein tyrosine phosphatase, non-receptor type 11, SH2 domain, in complex with phosphotyrosine peptide Target Class: Phosphatases Disease Areas: Signalling Site: Toronto Status: Follow-up official


	PDB: 5CBD Target: PP-PKG Deposited: 30/06/2015 Plasmodium vivax protein kinase G in complex with a small molecule inhibitor Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 5C8H Target: ORC2 Deposited: 25/06/2015 Human origin recognition complex, subunit 2, C-terminal domain Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Pending-Official Structure


	PDB: 5C8G Target: PP-BRD20 Deposited: 25/06/2015 Trypanosoma brucei Tb427tmp.01.1830, bromodomain, in complex with inhibitor Target Class: Bromodomain Disease Areas: Site: Toronto Status: Pending-Official Structure


	PDB: 5C7J Target: NEDD4 Deposited: 24/06/2015 Human neural precursor cell expressed, developmentally down-regulated 4 (E3 ubiquitin protein ligase), HECT domain, in complex with ubiquitin variant Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Cancer Site: Toronto Status: Official


	PDB: 5C7M Target: ITCH Deposited: 24/06/2015 Human itchy E3 ubiquitin protein ligase, HECT domain, in complex with a ubiquitin variant Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Cancer Site: Toronto Status: Official


	PDB: 5C6S Target: BRPF1 Deposited: 23/06/2015 Human Bromodomain and PHD Finger Containing 1, PWWP domain, in complex with fragment inhibitor Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Pending-Official Structure


	PDB: 5C65 Target: SLC2A3A Deposited: 22/06/2015 Human solute carrier family 2 (facilitated glucose transporter), member 3 Target Class: Membrane proteins Disease Areas: Drug metabolism and toxicology Site: Oxford Status: Pending-Official Structure


	PDB: 5C5C Target: GRM7 Deposited: 19/06/2015 Human metabotropic glutamate receptor 7, extracellular ligand binding domain Target Class: Miscellaneous Disease Areas: Signalling, Neurobiology Site: Toronto Status: Pending-Official Structure


	PDB: 5C4Q Target: LdBPK_363130 Deposited: 18/06/2015 Leishmania donovani BPK282A1 (LdBPK_363130.1) bromodomain in complex with Bromosporine Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5C0M Target: SGF29 Deposited: 12/06/2015 Human coiled-coil domain containing 101, tandem Tudor domain, in complex with peptidomimetic Target Class: Methyl-lysine readers Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5A4R Target: MMADHCMMA Deposited: 11/06/2015 Methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria Target Class: Miscellaneous Disease Areas: Metabolism Site: Oxford Status: Pending - Official structure


	PDB: 5A3W Target: JARID1BA Deposited: 03/06/2015 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Oxidoreductases Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5A3N Target: JARID1BA Deposited: 02/06/2015 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Oxidoreductases Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5A3P Target: JARID1BA Deposited: 02/06/2015 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5A3T Target: JARID1BA Deposited: 02/06/2015 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Oxidoreductases Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5BT3 Target: EP300A Deposited: 02/06/2015 Human E1A binding protein p300 Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5BT4 Target: BRD4A Deposited: 02/06/2015 Human bromodomain containing 4 [isoform long] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5BT5 Target: BRD2A Deposited: 02/06/2015 Human bromodomain containing 2 Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 4YLK Target: DYRK1AA Deposited: 02/06/2015 Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 4ZQL Target: TIF1A Deposited: 15/05/2015 Human transcriptional intermediary factor 1 Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5A1H Target: SPIN3A Deposited: 01/05/2015 Human spindlin-3 Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Pending - Official structure


	PDB: 5A1L Target: UTYC Deposited: 01/05/2015 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5A1F Target: JARID1BA Deposited: 29/04/2015 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Site: Oxford Status: Pending - Official structure


	PDB: 5A15 Target: KCTD16A Deposited: 28/04/2015 Human BTB/POZ domain-containing protein KCTD16 Target Class: Ubiquitin Related Biology Disease Areas: Site: Oxford Status: Official


	PDB: 5A14 Target: CDK2A Deposited: 27/04/2015 Human cyclin-dependent kinase 2 [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5AME Target: BRD1A Deposited: 10/04/2015 Human bromodomain containing protein 1 Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5AMF Target: BRD1A Deposited: 10/04/2015 Huma bromodomain containing protein 1 Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 4Z6H Target: BRD9A Deposited: 05/04/2015 Human bromodomain containing 9 [isoform 1] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 4Z6I Target: BRD9A Deposited: 05/04/2015 Human bromodomain containing 9 [isoform 1] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 4Z3C Target: TET3 Deposited: 31/03/2015 Human tet methylcytosine dioxygenase 3, CXXC domain, in complex with DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Pending-Official Structure


	PDB: 4UIJ Target: KCTD13A Deposited: 30/03/2015 Human BTB/POZ domain-containing protein KCTD13 Target Class: Ubiquitin Related Biology Disease Areas: Site: Oxford Status: Official


	PDB: 4Z30 Target: RC3H2 Deposited: 30/03/2015 Human ring finger and CCCH-type domains 2 (Roquin-2) Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: Official


	PDB: 4Z31 Target: RC3H2 Deposited: 30/03/2015 Human ring finger and CCCH-type domains 2 (Roquin-2), in complex with RNA Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: Official


	PDB: 4Z02 Target: BRD1 Deposited: 25/03/2015 Human bromodomain containing 1, PWWP domain, in complex with fragment inhibitor Target Class: Methyl-lysine readers Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 4YZ8 Target: WHSC1L1 Deposited: 25/03/2015 Human Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1/NSD3), methyltransferase domain, in complex with the cofactor S-adenosylmethionine Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Pending-Official Structure


	PDB: 4YVD Target: PLRG1 Deposited: 23/03/2015 Human pleiotropic regulator 1, WD repeat Target Class: Miscellaneous Disease Areas: Signalling Site: Toronto Status: Pending-Official Structure


	PDB: 4YWQ Target: RC3H1 Deposited: 23/03/2015 Human ring finger and CCCH-type domains 1 (Roquin-1), ROQ domain Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: Follow-up not counted


	PDB: 4YY8 Target: PF13_0238 Deposited: 23/03/2015 Plasmodium falciparum kelch protein K13 (PF3D7_1343700/PF13_0238), BTB/Poz and galactose oxidase/beta-propeller domains Target Class: Miscellaneous Disease Areas: Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 4Z0O Target: ZCWPW2 Deposited: 23/03/2015 Human zinc finger, CW type with PWWP domain 2 (F78D mutant), Znf_CW domain Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 4Z0R Target: ZCWPW2 Deposited: 23/03/2015 Human zinc finger, CW type with PWWP domain 2 (F78R mutant), Znf_CW domain Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 4YU2 Target: DYRK1AA Deposited: 18/03/2015 Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 4YLJ Target: DYRK1AA Deposited: 05/03/2015 Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 4YLL Target: DYRK1AA Deposited: 05/03/2015 Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5AK7 Target: PG1424PGA Deposited: 02/03/2015 Human PG1424 peptidylarginine deiminase Target Class: Miscellaneous Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5AK8 Target: PG1424PGA Deposited: 02/03/2015 Human PG1424 peptidylarginine deiminase Target Class: Miscellaneous Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 5AJQ Target: STK10A Deposited: 26/02/2015 Human serine/threonine kinase 10 Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Pending-Official Structure


	PDB: 4Y8D Target: XX03GAKA Deposited: 16/02/2015 Human crystal structure of Cyclin-G associated kinase (GAK) complexed with selective 12i inhibitor Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5AIK Target: DYRK1AA Deposited: 15/02/2015 Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5AIL Target: PARP9B Deposited: 15/02/2015 Human PARP9 protein Target Class: Poly ADP-ribose polymerase Disease Areas: Chromatin and epigenetics Site: Oxford Status: Pending-Official Structure


	PDB: 5AHR Target: DCLRE1AA Deposited: 06/02/2015 Human DNA cross-link repair 1A Target Class: Miscellaneous Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 4Y03 Target: PB1A Deposited: 05/02/2015 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 4XY8 Target: BRD9A Deposited: 02/02/2015 Human bromodomain containing 9 [isoform 1] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 4XY9 Target: BRD4A Deposited: 02/02/2015 Human bromodomain containing 4 [isoform long] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 4XYA Target: BRD4A Deposited: 02/02/2015 Human bromodomain containing 4 [isoform long] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5AGA Target: POLQA Deposited: 30/01/2015 Human DNA polymerase theta [isoform 1] Target Class: Miscellaneous Disease Areas: Site: Oxford Status: Pending-Official Structure


	PDB: 4XUA Target: BAZ2BA Deposited: 25/01/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 4XUB Target: BAZ2BA Deposited: 25/01/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 4XWX Target: SHC1A Deposited: 25/01/2015 Human SHC (Src homology 2 domain containing) transforming protein 1 isoform p66Shc Target Class: Miscellaneous Disease Areas: Site: Oxford Status: Pending-Official Structure


	PDB: 4UF0 Target: UTYC Deposited: 22/12/2014 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 4XDJ Target: KCNK10C Deposited: 19/12/2014 Human potassium channel, subfamily K, member 10 [isoform 3] Target Class: Membrane proteins Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 4XDK Target: KCNK10C Deposited: 19/12/2014 Human potassium channel, subfamily K, member 10 [isoform 3] Target Class: Membrane proteins Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 4XDL Target: KCNK10C Deposited: 19/12/2014 Human potassium channel, subfamily K, member 10 [isoform 3] Target Class: Membrane proteins Disease Areas: Site: Oxford Status: Follow-up official