Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway. Read more about Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway.
The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains. Read more about The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains.
Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor. Read more about Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor.
5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation. Read more about 5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.
Human ISPD Is a Cytidyltransferase Required for Dystroglycan O-Mannosylation. Read more about Human ISPD Is a Cytidyltransferase Required for Dystroglycan O-Mannosylation.
Structural biology and chemistry of protein arginine methyltransferases. Read more about Structural biology and chemistry of protein arginine methyltransferases.
Docking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors. Read more about Docking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors.
Profiling of Small Molecules by Chemical Proteomics. Read more about Profiling of Small Molecules by Chemical Proteomics.
SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Read more about SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination.
A Radioactivity-Based Assay for Screening Human m6A-RNA Methyltransferase, METTL3-METTL14 Complex, and Demethylase ALKBH5. Read more about A Radioactivity-Based Assay for Screening Human m6A-RNA Methyltransferase, METTL3-METTL14 Complex, and Demethylase ALKBH5.
