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Accurate calculation of the absolute free energy of binding for drug molecules.

  • Read more about Accurate calculation of the absolute free energy of binding for drug molecules.

EXD2 promotes homologous recombination by facilitating DNA end resection.

  • Read more about EXD2 promotes homologous recombination by facilitating DNA end resection.

A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1.

  • Read more about A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1.

Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor.

  • Read more about Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor.

Identification of LACTB2, a metallo-β-lactamase protein, as a human mitochondrial endoribonuclease.

  • Read more about Identification of LACTB2, a metallo-β-lactamase protein, as a human mitochondrial endoribonuclease.

Family-wide Structural Analysis of Human Numb-Associated Protein Kinases.

  • Read more about Family-wide Structural Analysis of Human Numb-Associated Protein Kinases.

Apollo-NADP(+): a spectrally tunable family of genetically encoded sensors for NADP(.)

  • Read more about Apollo-NADP(+): a spectrally tunable family of genetically encoded sensors for NADP(.)

Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform.

  • Read more about Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform.

Lessons from ten years of crystallization experiments at the SGC.

  • Read more about Lessons from ten years of crystallization experiments at the SGC.

Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.

  • Read more about Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.

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