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Type II inhibitors targeting CDK2.

  • Read more about Type II inhibitors targeting CDK2.

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.

  • Read more about Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.

The promise and peril of chemical probes.

  • Read more about The promise and peril of chemical probes.

Probing the epigenome.

  • Read more about Probing the epigenome.

Structural basis of glycogen branching enzyme deficiency and pharmacologic rescue by rational peptide design.

  • Read more about Structural basis of glycogen branching enzyme deficiency and pharmacologic rescue by rational peptide design.

Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1).

  • Read more about Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1).

Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis.

  • Read more about Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis.

BET inhibition upregulates SIRT1 and alleviates inflammatory responses.

  • Read more about BET inhibition upregulates SIRT1 and alleviates inflammatory responses.

A Call for Systematic Research on Solute Carriers.

  • Read more about A Call for Systematic Research on Solute Carriers.

Defined PEG smears as an alternative approach to enhance the search for crystallization conditions and crystal-quality improvement in reduced screens.

  • Read more about Defined PEG smears as an alternative approach to enhance the search for crystallization conditions and crystal-quality improvement in reduced screens.

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