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A Potent, Selective and Cell-active Inhibitor of Human Type I Protein Arginine Methyltransferases.

  • Read more about A Potent, Selective and Cell-active Inhibitor of Human Type I Protein Arginine Methyltransferases.

Evidence That Compound I Is the Active Species in Both the Hydroxylase and Lyase Steps by Which P450scc Converts Cholesterol to Pregnenolone: EPR/ENDOR/Cryoreduction/Annealing Studies.

  • Read more about Evidence That Compound I Is the Active Species in Both the Hydroxylase and Lyase Steps by Which P450scc Converts Cholesterol to Pregnenolone: EPR/ENDOR/Cryoreduction/Annealing Studies.

MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin.

  • Read more about MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin.

Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway.

  • Read more about Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway.

The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains.

  • Read more about The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains.

Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor.

  • Read more about Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor.

5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.

  • Read more about 5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.

Human ISPD Is a Cytidyltransferase Required for Dystroglycan O-Mannosylation.

  • Read more about Human ISPD Is a Cytidyltransferase Required for Dystroglycan O-Mannosylation.

Structural biology and chemistry of protein arginine methyltransferases.

  • Read more about Structural biology and chemistry of protein arginine methyltransferases.

Docking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors.

  • Read more about Docking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors.

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