Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target. Read more about Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target.
Open Access Could Transform Drug Discovery: A Case Study of JQ1. Read more about Open Access Could Transform Drug Discovery: A Case Study of JQ1.
Accurate calculation of the absolute free energy of binding for drug molecules. Read more about Accurate calculation of the absolute free energy of binding for drug molecules.
EXD2 promotes homologous recombination by facilitating DNA end resection. Read more about EXD2 promotes homologous recombination by facilitating DNA end resection.
A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1. Read more about A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1.
Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor. Read more about Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor.
Identification of LACTB2, a metallo-β-lactamase protein, as a human mitochondrial endoribonuclease. Read more about Identification of LACTB2, a metallo-β-lactamase protein, as a human mitochondrial endoribonuclease.
Family-wide Structural Analysis of Human Numb-Associated Protein Kinases. Read more about Family-wide Structural Analysis of Human Numb-Associated Protein Kinases.
Apollo-NADP(+): a spectrally tunable family of genetically encoded sensors for NADP(.) Read more about Apollo-NADP(+): a spectrally tunable family of genetically encoded sensors for NADP(.)
Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform. Read more about Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform.
