Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening. Read more about Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening.
High resolution crystal structure of DPF3b in complex with an acetylated histone peptide. Read more about High resolution crystal structure of DPF3b in complex with an acetylated histone peptide.
Effect of BET Missense Mutations on Bromodomain Function, Inhibitor Binding and Stability. Read more about Effect of BET Missense Mutations on Bromodomain Function, Inhibitor Binding and Stability.
Chemical Biology Approaches for Characterization of Epigenetic Regulators. Read more about Chemical Biology Approaches for Characterization of Epigenetic Regulators.
Finding Inspiration in the Protein Data Bank to Chemically Antagonize Readers of the Histone Code. Read more about Finding Inspiration in the Protein Data Bank to Chemically Antagonize Readers of the Histone Code.
Structure-Activity Relationship Studies for Enhancer of Zeste Homologue 2 (EZH2) and Enhancer of Zeste Homologue 1 (EZH1) Inhibitors. Read more about Structure-Activity Relationship Studies for Enhancer of Zeste Homologue 2 (EZH2) and Enhancer of Zeste Homologue 1 (EZH1) Inhibitors.
Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche. Read more about Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche.
Structural basis of arginine asymmetrical dimethylation by PRMT6. Read more about Structural basis of arginine asymmetrical dimethylation by PRMT6.
New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms. Read more about New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms.
A germline mutation of CDKN2A and a novel RPLP1-C19MC fusion detected in a rare melanotic neuroectodermal tumor of infancy: a case report. Read more about A germline mutation of CDKN2A and a novel RPLP1-C19MC fusion detected in a rare melanotic neuroectodermal tumor of infancy: a case report.
