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First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor.

  • Read more about First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor.

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.

  • Read more about A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.

RAC1 Missense Mutations in Developmental Disorders with Diverse Phenotypes.

  • Read more about RAC1 Missense Mutations in Developmental Disorders with Diverse Phenotypes.

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

  • Read more about ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

Increased 15-PGDH expression leads to dysregulated resolution responses in stromal cells from patients with chronic tendinopathy.

  • Read more about Increased 15-PGDH expression leads to dysregulated resolution responses in stromal cells from patients with chronic tendinopathy.

Novel patient missense mutations in the HSD17B10 gene affect dehydrogenase and mitochondrial tRNA modification functions of the encoded protein.

  • Read more about Novel patient missense mutations in the HSD17B10 gene affect dehydrogenase and mitochondrial tRNA modification functions of the encoded protein.

Comprehensive Analysis of the Human SH3 Domain Family Reveals a Wide Variety of Non-canonical Specificities.

  • Read more about Comprehensive Analysis of the Human SH3 Domain Family Reveals a Wide Variety of Non-canonical Specificities.

Correction for Bagarova et al., "Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation".

  • Read more about Correction for Bagarova et al., "Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation".

Structural basis for the potent and selective binding of LDN-212854 to the BMP receptor kinase ALK2.

  • Read more about Structural basis for the potent and selective binding of LDN-212854 to the BMP receptor kinase ALK2.

Asymmetric mechanosensitivity in a eukaryotic ion channel.

  • Read more about Asymmetric mechanosensitivity in a eukaryotic ion channel.

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