Early-life antibiotic treatment enhances the pathogenicity of CD4+ T cells during intestinal inflammation. Read more about Early-life antibiotic treatment enhances the pathogenicity of CD4+ T cells during intestinal inflammation.
Functions of bromodomain-containing proteins and their roles in homeostasis and cancer. Read more about Functions of bromodomain-containing proteins and their roles in homeostasis and cancer.
Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16. Read more about Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16.
Design of a Biased Potent Small Molecule Inhibitor of the Bromodomain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies. Read more about Design of a Biased Potent Small Molecule Inhibitor of the Bromodomain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies.
Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma. Read more about Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma.
Chemical Probes Targeting Epigenetic Proteins: Applications Beyond Oncology. Read more about Chemical Probes Targeting Epigenetic Proteins: Applications Beyond Oncology.
Molecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2. Read more about Molecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2.
Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5. Read more about Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5.
The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity. Read more about The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity.
