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A novel image-based high throughput screening assay discovers therapeutic candidates for adult polyglucosan body disease.

  • Read more about A novel image-based high throughput screening assay discovers therapeutic candidates for adult polyglucosan body disease.

Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein.

  • Read more about Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein.

Selective targeting of Bromodomains of the Bromodomain-PHD Fingers family impairs osteoclast differentiation.

  • Read more about Selective targeting of Bromodomains of the Bromodomain-PHD Fingers family impairs osteoclast differentiation.

TFG facilitates outer coat disassembly on COPII transport carriers to promote tethering and fusion with ER-Golgi intermediate compartments.

  • Read more about TFG facilitates outer coat disassembly on COPII transport carriers to promote tethering and fusion with ER-Golgi intermediate compartments.

Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy.

  • Read more about Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy.

Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing.

  • Read more about Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing.

First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor.

  • Read more about First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor.

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.

  • Read more about A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.

RAC1 Missense Mutations in Developmental Disorders with Diverse Phenotypes.

  • Read more about RAC1 Missense Mutations in Developmental Disorders with Diverse Phenotypes.

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

  • Read more about ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

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