Inhibition of calcium dependent protein kinase 1 (CDPK1) by pyrazolopyrimidine analogs decreases establishment and reoccurrence of central nervous system disease by Toxoplasma gondii. Read more about Inhibition of calcium dependent protein kinase 1 (CDPK1) by pyrazolopyrimidine analogs decreases establishment and reoccurrence of central nervous system disease by Toxoplasma gondii.
Corrigendum: Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer. Read more about Corrigendum: Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer.
Disease Association and Druggability of WD40 Repeat Proteins. Read more about Disease Association and Druggability of WD40 Repeat Proteins.
Crystal structure of the WD40 domain of human PRPF19. Read more about Crystal structure of the WD40 domain of human PRPF19.
Structural Complexity in the KCTD Family of Cullin3-Dependent E3 Ubiquitin Ligases. Read more about Structural Complexity in the KCTD Family of Cullin3-Dependent E3 Ubiquitin Ligases.
Discovery of a highly selective cell-active inhibitor of KDM2/7. Read more about Discovery of a highly selective cell-active inhibitor of KDM2/7.
Synthesis and Demonstration of the Biological Relevance of sp(3) -rich Scaffolds Distantly Related to Natural Product Frameworks. Read more about Synthesis and Demonstration of the Biological Relevance of sp(3) -rich Scaffolds Distantly Related to Natural Product Frameworks.
Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety. Read more about Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety.
Discovery of a selective allosteric inhibitor targeting macrodomain 2 of poly-adenosine-diphosphate-ribose polymerases 14. Read more about Discovery of a selective allosteric inhibitor targeting macrodomain 2 of poly-adenosine-diphosphate-ribose polymerases 14.
A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer. Read more about A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.
