Structure-Activity Relationship Studies for Enhancer of Zeste Homologue 2 (EZH2) and Enhancer of Zeste Homologue 1 (EZH1) Inhibitors. Read more about Structure-Activity Relationship Studies for Enhancer of Zeste Homologue 2 (EZH2) and Enhancer of Zeste Homologue 1 (EZH1) Inhibitors.
Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche. Read more about Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche.
Structural basis of arginine asymmetrical dimethylation by PRMT6. Read more about Structural basis of arginine asymmetrical dimethylation by PRMT6.
New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms. Read more about New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms.
A germline mutation of CDKN2A and a novel RPLP1-C19MC fusion detected in a rare melanotic neuroectodermal tumor of infancy: a case report. Read more about A germline mutation of CDKN2A and a novel RPLP1-C19MC fusion detected in a rare melanotic neuroectodermal tumor of infancy: a case report.
Epigenetic Blockade of Neoplastic Transformation by Bromodomain and Extra-Terminal (BET) Domain Protein Inhibitor JQ-1. Read more about Epigenetic Blockade of Neoplastic Transformation by Bromodomain and Extra-Terminal (BET) Domain Protein Inhibitor JQ-1.
Structural biology: HDAC6 finally crystal clear. Read more about Structural biology: HDAC6 finally crystal clear.
Structural Basis of Intracellular TGF-β Signaling: Receptors and Smads. Read more about Structural Basis of Intracellular TGF-β Signaling: Receptors and Smads.
Chemical Inhibition of Protein Methyltransferases. Read more about Chemical Inhibition of Protein Methyltransferases.
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors. Read more about Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors.
