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Structure-based design of highly selective inhibitors of the CREB binding protein bromodomain.

  • Read more about Structure-based design of highly selective inhibitors of the CREB binding protein bromodomain.

Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.

  • Read more about Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.

Molecular basis for the methylation specificity of ATXR5 for histone H3.

  • Read more about Molecular basis for the methylation specificity of ATXR5 for histone H3.

Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel.

  • Read more about Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel.

Benzo-isoquinoline-diones As Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains.

  • Read more about Benzo-isoquinoline-diones As Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains.

The RNF168 paralog RNF169 defines a new class of ubiquitylated-histone reader involved in the response to DNA damage.

  • Read more about The RNF168 paralog RNF169 defines a new class of ubiquitylated-histone reader involved in the response to DNA damage.

A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.

  • Read more about A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.

Global survey of the immunomodulatory potential of common drugs.

  • Read more about Global survey of the immunomodulatory potential of common drugs.

Hyperactive locomotion in a Drosophila model is a functional readout for the synaptic abnormalities underlying fragile X syndrome.

  • Read more about Hyperactive locomotion in a Drosophila model is a functional readout for the synaptic abnormalities underlying fragile X syndrome.

Recombinant Protein Expression in E. coli : A Historical Perspective.

  • Read more about Recombinant Protein Expression in E. coli : A Historical Perspective.

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