Development of a monoclonal anti-ADAMTS-5 antibody that specifically blocks the interaction with LRP1. Read more about Development of a monoclonal anti-ADAMTS-5 antibody that specifically blocks the interaction with LRP1.
Tetrahydroisoquinoline-7-carboxamide Derivatives as New Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors. Read more about Tetrahydroisoquinoline-7-carboxamide Derivatives as New Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors.
Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family. Read more about Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.
Partial-occupancy binders identified by the Pan-Dataset Density Analysis method offer new chemical opportunities and reveal cryptic binding sites. Read more about Partial-occupancy binders identified by the Pan-Dataset Density Analysis method offer new chemical opportunities and reveal cryptic binding sites.
Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation. Read more about Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation.
MOB1 mediated phospho-recognition in the core mammalian Hippo pathway. Read more about MOB1 mediated phospho-recognition in the core mammalian Hippo pathway.
Structure-based design of highly selective inhibitors of the CREB binding protein bromodomain. Read more about Structure-based design of highly selective inhibitors of the CREB binding protein bromodomain.
Highly selective inhibition of histone demethylases by de novo macrocyclic peptides. Read more about Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.
Molecular basis for the methylation specificity of ATXR5 for histone H3. Read more about Molecular basis for the methylation specificity of ATXR5 for histone H3.
Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel. Read more about Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel.
