Structure-based design of highly selective inhibitors of the CREB binding protein bromodomain. Read more about Structure-based design of highly selective inhibitors of the CREB binding protein bromodomain.
Highly selective inhibition of histone demethylases by de novo macrocyclic peptides. Read more about Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.
Molecular basis for the methylation specificity of ATXR5 for histone H3. Read more about Molecular basis for the methylation specificity of ATXR5 for histone H3.
Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel. Read more about Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel.
Benzo-isoquinoline-diones As Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains. Read more about Benzo-isoquinoline-diones As Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains.
The RNF168 paralog RNF169 defines a new class of ubiquitylated-histone reader involved in the response to DNA damage. Read more about The RNF168 paralog RNF169 defines a new class of ubiquitylated-histone reader involved in the response to DNA damage.
A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Read more about A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.
Global survey of the immunomodulatory potential of common drugs. Read more about Global survey of the immunomodulatory potential of common drugs.
Hyperactive locomotion in a Drosophila model is a functional readout for the synaptic abnormalities underlying fragile X syndrome. Read more about Hyperactive locomotion in a Drosophila model is a functional readout for the synaptic abnormalities underlying fragile X syndrome.
Recombinant Protein Expression in E. coli : A Historical Perspective. Read more about Recombinant Protein Expression in E. coli : A Historical Perspective.