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Critical assessment of LC3/GABARAP ligands used for degrader development and ligandability of LC3/GABARAP binding pockets.

  • Read more about Critical assessment of LC3/GABARAP ligands used for degrader development and ligandability of LC3/GABARAP binding pockets.

Discovery of CHD1 Antagonists for PTEN-Deficient Prostate Cancer.

  • Read more about Discovery of CHD1 Antagonists for PTEN-Deficient Prostate Cancer.

The Chemical Probes Portal - 2024: update on this public resource to support best-practice selection and use of small molecules in biomedical research.

  • Read more about The Chemical Probes Portal - 2024: update on this public resource to support best-practice selection and use of small molecules in biomedical research.

The endocannabinoid anandamide mediates anti-inflammatory effects through activation of NR4A nuclear receptors.

  • Read more about The endocannabinoid anandamide mediates anti-inflammatory effects through activation of NR4A nuclear receptors.

Introducing AIRCHECK

  • Read more about Introducing AIRCHECK

A data platform intended for sharing and analyzing high-quality datasets of protein-small molecule binding data.

Contribute Your Purified Proteins to Accelerate Open Data in Drug Discovery

  • Read more about Contribute Your Purified Proteins to Accelerate Open Data in Drug Discovery

Our new initiative invites scientists from academia and industry to contribute purified proteins and support large-scale protein-ligand interaction screenings through Affinity Selection Mass Spectrometry (AS-MS) and DNA-encoded chemical libraries (DEL) assays, using industry-standard protocols.

Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach.

  • Read more about Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach.

The use of a multi-metric readout screen to identify EHMT2/G9a-inhibition as a modulator of cancer-associated fibroblast activation state.

  • Read more about The use of a multi-metric readout screen to identify EHMT2/G9a-inhibition as a modulator of cancer-associated fibroblast activation state.

A guide to selecting high-performing antibodies for CSNK2A1 (UniProt ID: P68400) for use in western blot, immunoprecipitation and immunofluorescence.

  • Read more about A guide to selecting high-performing antibodies for CSNK2A1 (UniProt ID: P68400) for use in western blot, immunoprecipitation and immunofluorescence.

A guide to selecting high-performing antibodies for PLC-gamma-2 for use in Western Blot, immunoprecipitation and immunofluorescence.

  • Read more about A guide to selecting high-performing antibodies for PLC-gamma-2 for use in Western Blot, immunoprecipitation and immunofluorescence.

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