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Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.

  • Read more about Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.

Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.

  • Read more about Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.

Allosteric Modulation of Binding Specificity by Alternative Packing of Protein Cores.

  • Read more about Allosteric Modulation of Binding Specificity by Alternative Packing of Protein Cores.

Arginine does not rescue p.Q188R mutation deleterious effect in classic galactosemia.

  • Read more about Arginine does not rescue p.Q188R mutation deleterious effect in classic galactosemia.

Guiding COMPASS: Dpy-30 Positions SET1/MLL Epigenetic Signaling.

  • Read more about Guiding COMPASS: Dpy-30 Positions SET1/MLL Epigenetic Signaling.

Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy?

  • Read more about Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy?

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

  • Read more about Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

Patients with anti-Jo1 antibodies display a characteristic IgG Fc-glycan profile which is further enhanced in anti-Jo1 autoantibodies.

  • Read more about Patients with anti-Jo1 antibodies display a characteristic IgG Fc-glycan profile which is further enhanced in anti-Jo1 autoantibodies.

Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway.

  • Read more about Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway.

Single-Molecule Protein Phosphorylation and Dephosphorylation by Nanopore Enzymology.

  • Read more about Single-Molecule Protein Phosphorylation and Dephosphorylation by Nanopore Enzymology.

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