Role of protein structure in variant annotation: structural insight of mutations causing 6-pyruvoyl-tetrahydropterin synthase deficiency. Read more about Role of protein structure in variant annotation: structural insight of mutations causing 6-pyruvoyl-tetrahydropterin synthase deficiency.
Solution structures and biophysical analysis of full-length group A PAKs reveal they are monomeric and auto-inhibited in cis. Read more about Solution structures and biophysical analysis of full-length group A PAKs reveal they are monomeric and auto-inhibited in cis.
Divergent roles of prostacyclin and PGE2 in human tendinopathy. Read more about Divergent roles of prostacyclin and PGE2 in human tendinopathy.
Targeting the Small GTPase Superfamily through their Regulatory Proteins. Read more about Targeting the Small GTPase Superfamily through their Regulatory Proteins.
4'-Phosphopantetheine and long acyl chain-dependent interactions are integral to human mitochondrial acyl carrier protein function. Read more about 4'-Phosphopantetheine and long acyl chain-dependent interactions are integral to human mitochondrial acyl carrier protein function.
Lrig2 and Hpse2, mutated in urofacial syndrome, pattern nerves in the urinary bladder. Read more about Lrig2 and Hpse2, mutated in urofacial syndrome, pattern nerves in the urinary bladder.
AKT drives SOX2 overexpression and cancer cell stemness in esophageal cancer by protecting SOX2 from UBR5-mediated degradation. Read more about AKT drives SOX2 overexpression and cancer cell stemness in esophageal cancer by protecting SOX2 from UBR5-mediated degradation.
Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X. Read more about Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X.
Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells. Read more about Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells.
Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming. Read more about Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming.
