A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Read more about A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Chromokinesins NOD and KID Use Distinct ATPase Mechanisms and Microtubule Interactions to Perform a Similar Function. Read more about Chromokinesins NOD and KID Use Distinct ATPase Mechanisms and Microtubule Interactions to Perform a Similar Function.
Design of a Cyclin G Associated Kinase (GAK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Set to Interrogate the Relationship of EGFR and GAK in Chordoma. Read more about Design of a Cyclin G Associated Kinase (GAK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Set to Interrogate the Relationship of EGFR and GAK in Chordoma.
Structural insights into the modulatory role of the accessory protein WYL1 in the Type VI-D CRISPR-Cas system. Read more about Structural insights into the modulatory role of the accessory protein WYL1 in the Type VI-D CRISPR-Cas system.
Structural analyses reveal that MBD3 is a methylated-CG binder. Read more about Structural analyses reveal that MBD3 is a methylated-CG binder.
Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome. Read more about Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome.
A Parsimonious Mechanism of Sugar Dehydration by Human GDP-Mannose-4,6-dehydratase. Read more about A Parsimonious Mechanism of Sugar Dehydration by Human GDP-Mannose-4,6-dehydratase.
Crystal structure of human RIOK2 bound to a specific inhibitor. Read more about Crystal structure of human RIOK2 bound to a specific inhibitor.
Discovery of Pyrrolo[3,2-d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell Active Inhibitors of P300/CBP-Associated Factor Bromodomain. Read more about Discovery of Pyrrolo[3,2-d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell Active Inhibitors of P300/CBP-Associated Factor Bromodomain.
A chemical toolbox for the study of bromodomains and epigenetic signaling. Read more about A chemical toolbox for the study of bromodomains and epigenetic signaling.
