A Parsimonious Mechanism of Sugar Dehydration by Human GDP-Mannose-4,6-dehydratase. Read more about A Parsimonious Mechanism of Sugar Dehydration by Human GDP-Mannose-4,6-dehydratase.
Crystal structure of human RIOK2 bound to a specific inhibitor. Read more about Crystal structure of human RIOK2 bound to a specific inhibitor.
Discovery of Pyrrolo[3,2-d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell Active Inhibitors of P300/CBP-Associated Factor Bromodomain. Read more about Discovery of Pyrrolo[3,2-d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell Active Inhibitors of P300/CBP-Associated Factor Bromodomain.
A chemical toolbox for the study of bromodomains and epigenetic signaling. Read more about A chemical toolbox for the study of bromodomains and epigenetic signaling.
Discovery of selective activators of PRC2 mutant EED-I363M. Read more about Discovery of selective activators of PRC2 mutant EED-I363M.
Construction of a Shape-Diverse Fragment Set: Design, Synthesis and Screen against Aurora-A Kinase. Read more about Construction of a Shape-Diverse Fragment Set: Design, Synthesis and Screen against Aurora-A Kinase.
Structure-guided fragment-based drug discovery at the synchrotron: screening binding sites and correlations with hotspot mapping. Read more about Structure-guided fragment-based drug discovery at the synchrotron: screening binding sites and correlations with hotspot mapping.
A Perspective on Extreme Open Science: Companies Sharing Compounds without Restriction. Read more about A Perspective on Extreme Open Science: Companies Sharing Compounds without Restriction.
Structure and function of eTudor domain containing TDRD proteins. Read more about Structure and function of eTudor domain containing TDRD proteins.
Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins. Read more about Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins.
