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CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function.

  • Read more about CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function.

Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry.

  • Read more about Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry.

Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63.

  • Read more about Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63.

Creation of a novel class of potent and selective MutT Homolog 1 (MTH1) inhibitors using fragment-based screening and structure-based drug design.

  • Read more about Creation of a novel class of potent and selective MutT Homolog 1 (MTH1) inhibitors using fragment-based screening and structure-based drug design.

Structural and histone binding studies of the chromo barrel domain of TIP60.

  • Read more about Structural and histone binding studies of the chromo barrel domain of TIP60.

Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation.

  • Read more about Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation.

New opportunities for kinase drug repurposing and target discovery.

  • Read more about New opportunities for kinase drug repurposing and target discovery.

Effects of FKBP12 and type II BMP receptors on signal transduction by ALK2 activating mutations associated with genetic disorders.

  • Read more about Effects of FKBP12 and type II BMP receptors on signal transduction by ALK2 activating mutations associated with genetic disorders.

Quantitative characterization of bivalent probes for a dual bromodomain protein, Transcription Initiation Factor TFIID subunit 1, TAF1.

  • Read more about Quantitative characterization of bivalent probes for a dual bromodomain protein, Transcription Initiation Factor TFIID subunit 1, TAF1.

Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain.

  • Read more about Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain.

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