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New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis.

  • Read more about New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis.

Response to: 'Potential roles for tenascin in (very) early diagnosis and treatment of rheumatoid arthritis' by Cutolo et al.

  • Read more about Response to: 'Potential roles for tenascin in (very) early diagnosis and treatment of rheumatoid arthritis' by Cutolo et al.

SGC-GAK-1: a chemical probe for cyclin G associated kinase (GAK).

  • Read more about SGC-GAK-1: a chemical probe for cyclin G associated kinase (GAK).

Teneurin C-Terminal Associated Peptide (TCAP)-1 and Latrophilin Interaction in HEK293 Cells: Evidence for Modulation of Intercellular Adhesion.

  • Read more about Teneurin C-Terminal Associated Peptide (TCAP)-1 and Latrophilin Interaction in HEK293 Cells: Evidence for Modulation of Intercellular Adhesion.

Structural insights into SETD3-mediated histidine methylation on β-actin.

  • Read more about Structural insights into SETD3-mediated histidine methylation on β-actin.

Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity.

  • Read more about Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity.

A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels.

  • Read more about A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels.

Organizational innovation for developing new medicines that target aging and age-related conditions.

  • Read more about Organizational innovation for developing new medicines that target aging and age-related conditions.

RNA interference may result in unexpected phenotypes in Caenorhabditis elegans.

  • Read more about RNA interference may result in unexpected phenotypes in Caenorhabditis elegans.

Design and characterization of mutant and wild-type huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems.

  • Read more about Design and characterization of mutant and wild-type huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems.

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