New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis. Read more about New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis.
Response to: 'Potential roles for tenascin in (very) early diagnosis and treatment of rheumatoid arthritis' by Cutolo et al. Read more about Response to: 'Potential roles for tenascin in (very) early diagnosis and treatment of rheumatoid arthritis' by Cutolo et al.
SGC-GAK-1: a chemical probe for cyclin G associated kinase (GAK). Read more about SGC-GAK-1: a chemical probe for cyclin G associated kinase (GAK).
Teneurin C-Terminal Associated Peptide (TCAP)-1 and Latrophilin Interaction in HEK293 Cells: Evidence for Modulation of Intercellular Adhesion. Read more about Teneurin C-Terminal Associated Peptide (TCAP)-1 and Latrophilin Interaction in HEK293 Cells: Evidence for Modulation of Intercellular Adhesion.
Structural insights into SETD3-mediated histidine methylation on β-actin. Read more about Structural insights into SETD3-mediated histidine methylation on β-actin.
Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity. Read more about Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity.
A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels. Read more about A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels.
Organizational innovation for developing new medicines that target aging and age-related conditions. Read more about Organizational innovation for developing new medicines that target aging and age-related conditions.
RNA interference may result in unexpected phenotypes in Caenorhabditis elegans. Read more about RNA interference may result in unexpected phenotypes in Caenorhabditis elegans.
Design and characterization of mutant and wild-type huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems. Read more about Design and characterization of mutant and wild-type huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems.