A structure-based approach towards identification of inhibitory fragments for eleven-nineteen-leukemia protein (ENL). Read more about A structure-based approach towards identification of inhibitory fragments for eleven-nineteen-leukemia protein (ENL).
MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis. Read more about MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.
An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2. Read more about An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2.
Selective inhibitors of a human prolyl hydroxylase (OGFOD1) involved in ribosomal decoding. Read more about Selective inhibitors of a human prolyl hydroxylase (OGFOD1) involved in ribosomal decoding.
Design, Synthesis and Characterization of Covalent KDM5 Inhibitors. Read more about Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.
Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex. Read more about Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.
Allosteric Modulation of Binding Specificity by Alternative Packing of Protein Cores. Read more about Allosteric Modulation of Binding Specificity by Alternative Packing of Protein Cores.
Arginine does not rescue p.Q188R mutation deleterious effect in classic galactosemia. Read more about Arginine does not rescue p.Q188R mutation deleterious effect in classic galactosemia.
Guiding COMPASS: Dpy-30 Positions SET1/MLL Epigenetic Signaling. Read more about Guiding COMPASS: Dpy-30 Positions SET1/MLL Epigenetic Signaling.
Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy? Read more about Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy?
