Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40. Read more about Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40.
Leucettinibs, a Class of DYRK/CLK Kinase Inhibitors Inspired by the Marine Sponge Natural Product Leucettamine B. Read more about Leucettinibs, a Class of DYRK/CLK Kinase Inhibitors Inspired by the Marine Sponge Natural Product Leucettamine B.
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology. Read more about Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology.
5-Iodotubercidin sensitizes cells to RIPK1-dependent necroptosis by interfering with NFκB signaling. Read more about 5-Iodotubercidin sensitizes cells to RIPK1-dependent necroptosis by interfering with NFκB signaling.
The Canadian Open Neuroscience Platform-An open science framework for the neuroscience community. Read more about The Canadian Open Neuroscience Platform-An open science framework for the neuroscience community.
Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6. Read more about Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6.
The identification of high-performing antibodies for transmembrane protein 106B (TMEM106B) for use in Western blot, immunoprecipitation, and immunofluorescence. Read more about The identification of high-performing antibodies for transmembrane protein 106B (TMEM106B) for use in Western blot, immunoprecipitation, and immunofluorescence.
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Read more about Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
SETD7 functions as a transcription repressor in prostate cancer via methylating FOXA1. Read more about SETD7 functions as a transcription repressor in prostate cancer via methylating FOXA1.
SETDB1 Triple Tudor Domain Ligand, (R,R)-59, Promotes Methylation of Akt1 in Cells. Read more about SETDB1 Triple Tudor Domain Ligand, (R,R)-59, Promotes Methylation of Akt1 in Cells.