Antecedent chromatin organization determines cGAS recruitment to ruptured micronuclei. Read more about Antecedent chromatin organization determines cGAS recruitment to ruptured micronuclei.
Discovery of potent Plasmodium falciparum protein kinase 6 (PfPK6) inhibitors with a type II inhibitor pharmacophore. Read more about Discovery of potent Plasmodium falciparum protein kinase 6 (PfPK6) inhibitors with a type II inhibitor pharmacophore.
SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses. Read more about SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses.
Toward effective Atg8-based ATTECs: Approaches and perspectives. Read more about Toward effective Atg8-based ATTECs: Approaches and perspectives.
Discovery and Characterization of BAY-805, a Potent and Selective Inhibitor of Ubiquitin-Specific Protease USP21. Read more about Discovery and Characterization of BAY-805, a Potent and Selective Inhibitor of Ubiquitin-Specific Protease USP21.
Histone H4K20 monomethylation enables recombinant nucleosome methylation by PRMT1 in vitro. Read more about Histone H4K20 monomethylation enables recombinant nucleosome methylation by PRMT1 in vitro.
Discovery and Development Strategies for SARS-CoV-2 NSP3 Macrodomain Inhibitors. Read more about Discovery and Development Strategies for SARS-CoV-2 NSP3 Macrodomain Inhibitors.
RAS and PP2A activities converge on epigenetic gene regulation. Read more about RAS and PP2A activities converge on epigenetic gene regulation.
Chemistry-led investigations into the mode of action of NAMPT activators, resulting in the discovery of non-pyridyl class NAMPT activators. Read more about Chemistry-led investigations into the mode of action of NAMPT activators, resulting in the discovery of non-pyridyl class NAMPT activators.
Design, synthesis and characterisation of a novel type II B-RAF paradox breaker inhibitor. Read more about Design, synthesis and characterisation of a novel type II B-RAF paradox breaker inhibitor.
