The orphan nuclear receptor Nurr1 is responsive to non-steroidal anti-inflammatory drugs. Read more about The orphan nuclear receptor Nurr1 is responsive to non-steroidal anti-inflammatory drugs.
A triple farnesoid X receptor and peroxisome proliferator-activated receptor α/δ activator reverses hepatic fibrosis in diet-induced NASH in mice. Read more about A triple farnesoid X receptor and peroxisome proliferator-activated receptor α/δ activator reverses hepatic fibrosis in diet-induced NASH in mice.
Epigenetic modulation by targeting bromodomain containing protein 9 (BRD9): Its therapeutic potential and selective inhibition. Read more about Epigenetic modulation by targeting bromodomain containing protein 9 (BRD9): Its therapeutic potential and selective inhibition.
Death by a Thousand Cuts â€" Combining Kinase Inhibitors for Selective Target Inhibition and Rational Polypharmacology. Read more about Death by a Thousand Cuts â€" Combining Kinase Inhibitors for Selective Target Inhibition and Rational Polypharmacology.
Antecedent chromatin organization determines cGAS recruitment to ruptured micronuclei. Read more about Antecedent chromatin organization determines cGAS recruitment to ruptured micronuclei.
Discovery of potent Plasmodium falciparum protein kinase 6 (PfPK6) inhibitors with a type II inhibitor pharmacophore. Read more about Discovery of potent Plasmodium falciparum protein kinase 6 (PfPK6) inhibitors with a type II inhibitor pharmacophore.
SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses. Read more about SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses.
Toward effective Atg8-based ATTECs: Approaches and perspectives. Read more about Toward effective Atg8-based ATTECs: Approaches and perspectives.
Discovery and Characterization of BAY-805, a Potent and Selective Inhibitor of Ubiquitin-Specific Protease USP21. Read more about Discovery and Characterization of BAY-805, a Potent and Selective Inhibitor of Ubiquitin-Specific Protease USP21.
Histone H4K20 monomethylation enables recombinant nucleosome methylation by PRMT1 in vitro. Read more about Histone H4K20 monomethylation enables recombinant nucleosome methylation by PRMT1 in vitro.
