Development of Cell Permeable NanoBRET Probes for the Measurement of PLK1 Target Engagement in Live Cells. Read more about Development of Cell Permeable NanoBRET Probes for the Measurement of PLK1 Target Engagement in Live Cells.
Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis. Read more about Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis.
Discovery of a Potent and Selective Naphthyridine-Based Chemical Probe for Casein Kinase 2. Read more about Discovery of a Potent and Selective Naphthyridine-Based Chemical Probe for Casein Kinase 2.
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. Read more about Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective.
Structural insights into DNA recognition by the BEN domain of the transcription factor BANP. Read more about Structural insights into DNA recognition by the BEN domain of the transcription factor BANP.
Shifting the selectivity of pyrido[2,3-d]pyrimidin-7(8H)-one inhibitors towards the salt-inducible kinase (SIK) subfamily. Read more about Shifting the selectivity of pyrido[2,3-d]pyrimidin-7(8H)-one inhibitors towards the salt-inducible kinase (SIK) subfamily.
NMR resonance assignment of a fibroblast growth factor 8 splicing isoform b. Read more about NMR resonance assignment of a fibroblast growth factor 8 splicing isoform b.
Editorial: The next generation of tools and technologies for studying human neurons in a dish. Read more about Editorial: The next generation of tools and technologies for studying human neurons in a dish.
A Small Step Toward Generalizability: Training a Machine Learning Scoring Function for Structure-Based Virtual Screening. Read more about A Small Step Toward Generalizability: Training a Machine Learning Scoring Function for Structure-Based Virtual Screening.
A novel BRET-based assay to investigate binding and residence times of unmodified ligands to the human lysosomal ion channel TRPML1 in intact cells. Read more about A novel BRET-based assay to investigate binding and residence times of unmodified ligands to the human lysosomal ion channel TRPML1 in intact cells.
